Fagonia cretica L.Synonyms: Fagonia deflexa Moench, Fagonia elongata Salisb., Fagonia erecta Mill., Fagonia forskalii Pfund, Fagonia hispanica L., Fagonia virens Coss. ex T.Anderson, Fagonia viscosa Hochst. ex Boiss.
Correct name for Indian sp. is Fagonia schweifurthii Hadidi. F. bruguieri DC. is not a synonym of F. cretica, (Indian Medicinal Plants an Illustrated Dictionary)
according to CDRI.)
Sanskrit: Dhanvayasah, Duhsparsha, Duralambha, Virupa, Duralabha, Ushtrabhaksha
Bengali: Duralabha
English: Khorasan thorn
Gujrati: Dhamaaso
Hindi: Damahan, Dhamaasa, Hinguaa, Dhanhare
Malayalam: Kodittuva
Marathi: Dhamaasaa
Punjabi: Dama, Dhamah, Dhamaha
Tamil: Tulganari
Telugu: Chittigava, Gilaregati
Unani: Dhamaasaa
Ayurvedic uses: Daha, Grahani, Gulma, Jvara, Kasa, Kushta, Prameha, Raktapitta, Vatarakta, Visarpa, Atisara, Visama jvara, Trishna, Moha, Murccha, Madaroga,Rakatavikara, Bharama, Chardi, Mutraghata.
Astringent, antiseptic, blood-purifier and febrifuge. Applied to abscesses, scrofulous glands and wounds; also given as a prophylactic against smallpox. Bark—used for dermatosis Extract of aerial parts—antiviral, antiamphetaminic, spasmogenic. Plant ash—given to children suffering from anaemia.
Fagonia cretica herbal tea arrested the growth of cancer cells within five hours of application and caused them to die within 24 hours. Source: Times of India Dt.23 Aug. 2012
35 Published articles of Fagonia cretica
1. An Aqueous Extract of Fagonia cretica Induces DNA Damage, Cell Cycle Arrest and Apoptosis in Breast Cancer Cells via FOXO3a and p53 Expression
Lam, Matt; Carmichael, Amtul R.; Griffiths, Helen R. - PLOS ONE Volume: 7 Issue: 6 Article Number: e40152 DOI: http;//dx.doi.org/10.1371/
2. An Aqueous Extract of Fagonia cretica Induces DNA Damage, Cell Cycle Arrest and Apoptosis in Breast Cancer Cells via FOXO3a and p53 Expression.
Lam, Matt; Carmichael, Amtul R; Griffiths, Helen R - PloS one Volume: 7 Issue: 6 Pages: e40152 Published: 2012 (Epub 2012 Jun 27)
3. Antihaemorrhagic potentials of Fagonia cretica against Naja naja karachiensis (black Pakistan cobra) venom
Razi, Muhammad Tahir; Bin Asad, Muhammad Hassham Hassan; Khan, Taous; et al. - NATURAL PRODUCT RESEARCH Volume: 25 Issue: 20 Pages: 1902-1907 DOI: http;//dx.doi.org/10.1080/
4. Phytochemical screening and antimicrobial activity of Fagonia cretica plant extracts against selected microbes.
Sajid, B.; Alia, E.; Rizwana, K.; et al. - Journal of Pharmacy Research Volume: 4 Issue: 4 Pages: 962-963 Published: 2011
5. Antimicrobial Constituents from Fagonia cretica
Anjum, Muhammad Imran; Ahmed, Ejaz; Jabbar, Abdul; et al. - JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN Volume: 29 Issue: 6 Pages: 634-639 Published: DEC 2007
6. Cytotoxic and antitumor potential of Fagonia cretica L.
Ahsan Hussain; Muhammad Zia; Bushra Mirza - Turkish Journal of Biology Volume: 31 Issue: 1 Pages: 19-24 Published: 2007
7. Cytotoxic and antitumor potential of Fagonia cretica L.
Hussain, Ahsan; Zia, Muhammad; Mirza, Bushra - Turkish Journal of Biology Volume: 31 Issue: 1 Pages: 19-24 Published: 2007
8. Antimicrobial efficacy of methanolic extracts of Fagonia cretica
Thetwar, LK; Thakur, AS; Shrivastava, S; et al. - ASIAN JOURNAL OF CHEMISTRY Volume: 18 Issue: 1 Pages: 743-744 Published: JAN-MAR 2006
9. Effect of Rubia cordifolia, Fagonia cretica linn, and Tinospora cordifolia on free radical generation and lipid peroxidation during oxygen-glucose deprivation in rat hippocampal slices
Rawal, A; Muddeshwar, M; Biswas, S - BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Volume: 324 Issue: 2 Pages: 588-596 DOI: http;//dx.doi.org/10.1016/j.
10. Rubia cordifolia, Fagonia cretica linn and Tinospora cordifolia exert neuroprotection by modulating the antioxidant system in rat hippocampal slices subjected to oxygen glucose deprivation.
Rawal, Avinash K; Muddeshwar, Manohar G; Biswas, Saibal K - BMC complementary and alternative medicine Volume: 4 Pages: 11 DOI: http;//dx.doi.org/10.1186/
11. Effects of Fagonia cretica L. constituents on various haematological parameters in rabbits.
Asif Saeed, M; Wahid Sabir, A - Journal of ethnopharmacology Volume: 85 Issue: 2-3 Pages: 195-200 DOI: http;//dx.doi.org/10.1016/
12. Effects of Fagonia cretica L. constituents on various haematological parameters in rabbits
Saeed, MA; Sabir, AW - JOURNAL OF ETHNOPHARMACOLOGY Volume: 85 Issue: 2-3 Pages: 195-200 DOI: http;//dx.doi.org/10.1016/
13. Autecological studies on Fagonia cretica, L. affecting its active constituent.
Emam, S. S.; Tolba, I. A. M. - Annals of Agricultural Science, Moshtohor Volume: 40 Issue: 2 Pages: 1183-1202 Published: 2002
14. Production of endogenous ascorbic acid from tissue cultures of Fagonia cretica Linn.
Kapoor, B. B. S. - Journal of Phytological Research Volume: 15 Issue: 1 Pages: 111-112 Published: 2002
15. Further saponins from Fagonia cretica
Abdel-Khalik, SM; Miyase, T; Melek, FR; et al. - PHARMAZIE Volume: 56 Issue: 3 Pages: 247-250 Published: MAR 2001
16. Triterpenoid saponins from Fagonia cretica.
Abdel Khalik, S M; Miyase, T; El-Ashaal, H A; et al. - Phytochemistry Volume: 54 Issue: 8 Pages: 853-9 Published: 2000-Aug
17. Triterpenoid saponins from Fagonia cretica
Khalik, SMA; Miyase, T; El-Ashaal, HA; et al. - PHYTOCHEMISTRY Volume: 54 Issue: 8 Pages: 853-859 DOI: http;//dx.doi.org/10.1016/
18. Trace elements in indigenous medicinal plants (Rhazya stricta, Vinca rosea and Fagonia cretica)
Fatima, Kaneez; Shirin, Khaula; Ali Kalhoro, Mahboob; et al. - Pakistan Journal of Scientific and Industrial Research Volume: 42 Issue: 4 Pages: 182-183 Published: Aug., 1999
19. Trace elements in indigenous medicinal plants ( Rhazya stricta, Vinca rosea and Fagonia cretica).
Kaneez Fatima; Khaula Shirin; Kalhoro, M. A.; et al. - Pakistan Journal of Scientific and Industrial Research Volume: 42 Issue: 4 Pages: 182-183 Published: 1999
20. Effects of Fagonia cretica L. constituents on various endocrinological parameters in rabbits
Saeed, M. Asif; Khan, Zaheer-ul-Din; Sabir, A. W. - Turkish Journal of Biology Volume: 23 Issue: 2 Pages: 187-197 Published: 1999
21. Biological properties of saponin mixtures of Fagonia cretica and Fagonia mollis
El-Shabrawy, O. A.; El-Gindi, K. O.; Melek, F. R.; et al. - Fitoterapia Volume: 68 Issue: 3 Pages: 219-222 Published: 1997
22. Investigation on fagonia cretica -its effect on hormonal profile and immunomodulation in rats.
Abirami, V; Khosa, R L; Dhar, S K; et al. - Ancient science of life Volume: 15 Issue: 4 Pages: 259-63 Published: 1996-Apr
23. New saponins from Fagonia cretica
Melek, F. R.; Abdel-Khalik, S. M.; Miyase, Toshio; et al. - Fitoterapia Volume: 65 Issue: 4 Pages: 363-366 Published: 1994
24. Toxicological study of the new molluscicidal plants: Fagonia cretica and Agave filifera
Ebeid, Fatma A.; Badawy, Afkar A.; Mostafa, Ahmed M.; et al. - Egyptian Journal of Bilharziasis Volume: 13 Issue: 1-2 Pages: 171-179 Published: 1991 (1992)
25. REMOVAL OF SEED DORMANCY BY GA-3 IN FAGONIA-CRETICA L. A TYPICAL INDIAN DESERT SPECIES
MOHAMMED S; SEN D N - Indian Botanical Reporter Volume: 7 Issue: 1-2 Pages: 95-96 Published: 1988
26. EFFECT OF FAGONIA-CRETICA ON SERUM PROLACTIN THYROTROPIN TSH THYROXINE T-4 AND CORTISOL LEVELS IN RABBITS
RASHEED A; JANBAZ K H; KHAN S M; et al. - Pakistan Veterinary Journal Volume: 8 Issue: 3 Pages: 114-118 Published: 1988
27. Molluscicidal activity of Fagonia cretica and Atriplex leucoclada.
Shoeb, H A; el-Emam, M A; Saad, A M; et al. - Journal of the Egyptian Society of Parasitology Volume: 17 Issue: 2 Pages: 539-46 Published: 1987-Dec
28. WATER-SOLUBLE PROTEIN FROM FAGONIA-CRETICA LINN
SHAUKAT, GA; MALIK, MA; AHMAD, MS - PAKISTAN JOURNAL OF BOTANY Volume: 13 Issue: 1 Pages: 99-101 Published: 1981
29. THE ISOLATION AND IDENTIFICATION OF ACTIVE PRINCIPLES FROM FAGONIA-CRETICA IDENTIFICATION OF FATTY-ACIDS BY THIN LAYER CHROMATOGRAPHY
ARAYNE M S; SAIFY Z S; NAIM Z - Journal of Science (Karachi) Volume: 4 Issue: (SUPPL) Pages: 105-108 Published: 1976
30. CHEMICAL INVESTIGATION OF FAGONIA-CRETICA
IYER A; JOSHI B C - Herba Polonica Volume: 21 Issue: 4 Pages: 420-423 Published: 1975
31. ISOLATION OF OLEANOLIC-ACID FROM FAGONIA-CRETICA-D
RIMPLER H; RIZK A M - Phytochemistry (Oxford) Volume: 8 Issue: 11 Pages: 2269 DOI: http;//dx.doi.org/10.1016/
32. INTRAINDIVIDUAL NUMERICAL CHROMOSOME INSTABILITY IN FAGONIA CRETICA L
BAQUAR, SR - GENETICA IBERICA Volume: 19 Issue: 1-2 Pages: 99-& Published: 1967
33. TRI TERPENOIDS II ANOTHER SAPOGENIN FROM FAGONIA-CRETICA-D ZYGOPHYLLACEAE-D
ALI M A; HAMEED Z - Pakistan Journal of Scientific and Industrial Research Volume: 10 Issue: 2 Pages: 140-141 Published: 1967
34. CHEMICAL EXAMINATION OF PLANT FAGONIA CRETICA LINN .2.
TANDON, SP; TIWARI, KP - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES INDIA SECTION A-PHYSICAL SCIENCES Volume: 37 Pages: 173-& Part: Part 2 Published: 1967
35. Description de deux Zoocecidies nouvelles sur Fagonia cretica L.
Houard, C. - Bulletin de la Societe Entomologique de France Pages: pp. 44-46 Published: 1901
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