Elephantopus scaber Linn.Family: Asteraceae
Vernacular names:
Bengali: হস্তী পাদ hasti pada, Gojialata, Shamdulum ,
Chinese: 地胆草, ku di dan
English: Elephant foot, False tobacco, Prickly-leaved elephant’s foot
Gujarati: Bhopathari
Hindi: अधोमुख adhomukha, बन तम्बाखू ban-tambakhu, गोभी gobhi
Jawa: Tapak liman
Kannada: ಆನೆಕಾಲು ಗಿಡ aanekaalu gida, ಹಸ್ತಿ ಪಾದ hasti pada, Hakkarike
Konkani: hakkarike
Malayalam: ആനച്ചുവടി aanaccuvati
Marathi: हस्तीपात hastipata, पातरी OR पाथरी pathari
Nepalese: सहस्त्र बुटि sahasra buti
Oriya: mayurachula
Sanskrit: अधपातः adhapata, गोजिह्वा gojihva OR गोजिव्हा gojivha, खरपर्णिनी kharaparnini, प्रस्तरिणी prastarini, Karipadam
Tamil: யானைச்சுவடி yanai-c-cuvati
Telugu: Enugu tamara ఏనుగు తామర
Urdu: گوبهی gobhi
Burmese: Katoopin
French: lastron marron
Taiwan: teng khia
Filipino: dila dila
Ayurvedic Uses: Astringent, alterative, febrifuge, Antimicrobial.
In Burma, a decoction of the aerial parts is drunk to treat irregular menses. In China, the plant is eaten as a salad and is a believed to improve general health. In several Southeast Asian countries the plant is used to break fevers and prompt urination. [Ethnopharmacology of Medicinal Plants Asia and the Pacific]
The effect of aqueous ethanol extracts and the isolated compound deoxyelephantopin from E. scaber Linn. was evaluated on excision, incision, and dead space wound models in rats. The wound-healing activity was assessed by the rate of wound contraction, period of epithelialization, skin-breaking strength, weight of the granulation tissue, and collagen content. Histological study of the granulation tissue was carried out to know the extent of collagen formation in the wound tissue.
Plant—astringent, cardiac tonic, diuretic, mucilaginous, emmolient (used in dysuria, diarrhoea, dysentery. Leaves applied to ulcers and eczema. Roots—given to patients with heart and liver affections; topically in rheumatism. Root and leaf— used in dysuria and other urethral complaints. An infusion of the whole plant is used to stimulate diuresis, reduce fever and to eliminate bladder stones. The decoction is also used in peptic ulcers, swelling or pain in stomach. Plant is also used in piles and scabies. [Indian Medicinal Plants Ayurveda]
In Burma, a decoction of the stems and leaves is drunk to regulate menses. In Malaysia, the scraping of the roots in betel quid is used to curb vomiting and the leaves are eaten as salad by Chinese. InVietnam, the plant is used to promote urination and recovery from childbirth. A decoction of the entire plant is used to treat pulmonary diseases and to soothe inflamed parts. A decoction of the leaves is used to treat venereal diseases. In India, the plant is used to invigorate health, relieve the bowels from costiveness, assuage pain, soothe inflammation and to stimulate venereal desire. In the Philippines, the plant is used to combat fever and to promote urination. In Taiwan, the roots are used to assuage pain in the chest. In Indonesia, the roots pounded in water are used to treat leucorrhea and anemia. The plant is used to promote urination and to combat fever. In China, the plant is used to promote urination and to soothe inflammation. [Medicinal Plants of The Aisa-Pacific: Drugs For The Future? ]
Whole plant: Decoction applied on mycoses (fungal diseases).[Medicinal Plants of the Guianas (Guyana, Surinam, French Guiana)]
Chemical Constituents: The plant contains germacranolide dilactones. Hydroxylated germacanolides, molephantin andmolephantinin, exhibited cytotoxic and antitumour properties. The plant also gave epifriedelanol, lupeol, stigmasterol, triacontan-l-ol and dotriacontan-l-ol. Plant contains deoxyelephantopine, an antitumoral sesquiterpene lactone.
45 Published articles of Elephantopus scaber
1. Evaluation of antiasthmatic activity of ethanolic extract of Elephantopus scaber L. leaves
Sagar, Rakesh; Sahoo, H. B. - INDIAN JOURNAL OF PHARMACOLOGY Volume: 44 Issue: 3 Pages: 398-401 DOI : http://dx.doi.org/: 10.4103/0253-7613.96347 Published: MAY-JUN 2012
2. Hepatoprotective Activity of Elephantopus scaber on Alcohol-Induced Liver Damage in Mice
Ho, Wan Yong; Yeap, Swee Keong; Ho, Chai Ling; et al. - EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE Article Number: 417953 DOI : http://dx.doi.org/: 10.1155/2012/417953 Published: 2012
3. Hepatoprotective Activity of Elephantopus scaber on Alcohol-Induced Liver Damage in Mice.
Ho, Wan Yong; Yeap, Swee Keong; Ho, Chai Ling; et al. - Evidence-based complementary and alternative medicine : eCAM Volume: 2012 Pages: 417953 Published: 2012 (Epub 2012 Aug 29)
4. Anti-bacterial studies on Hemigraphis colorata (Blume) HG Hallier and Elephantopus scaber L.
Anitha, Vimala Thankappan; Antonisamy, Johnson Marimuthu; Jeeva, Solomon - ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE Volume: 5 Issue: 1 Pages: 52-57 Published: JAN 2012
5. Sesquiterpene lactones isolated from Elephantopus scaber L. inhibits human lymphocyte proliferation and the growth of tumour cell lines and induces apoptosis in vitro.
Geetha, B S; Nair, Mangalam S; Latha, P G; et al. - Journal of biomedicine & biotechnology Volume: 2012 Pages: 721285 Published: 2012 (Epub 2012 Feb 01)
6. Sesquiterpene Lactones Isolated from Elephantopus scaber L. Inhibits Human Lymphocyte Proliferation and the Growth of Tumour Cell Lines and Induces Apoptosis In Vitro
Geetha, B. S.; Nair, Mangalam S.; Latha, P. G.; et al. - JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY Article Number: 721285 DOI : http://dx.doi.org/: 10.1155/2012/721285 Published: 2012
7. Elephantopus scaber induces cytotoxicity in MCF-7 human breast cancer cells via p53-induced apoptosis
Ho, Wan Yong; Yeap, Swee Keong; Ho, Chai Ling; et al. - JOURNAL OF MEDICINAL PLANTS RESEARCH Volume: 5 Issue: 24 Pages: 5741-5749 Published: OCT 30 2011
8. A study on the regenerative potential of the root and leaf extracts of Elephantopus scaber L.: An antidiabetic approach
Daisy, P.; Priya, Cecilia Edel; Vargese, Lily - AFRICAN JOURNAL OF PHARMACY AND PHARMACOLOGY Volume: 5 Issue: 16 Pages: 1832-1837 DOI : http://dx.doi.org/: 10.5897/AJPP10.332 Published: OCT 2011
9. Deoxyelephantopin from Elephantopus scaber L. induces cell-cycle arrest and apoptosis in the human nasopharyngeal cancer CNE cells
Su, Miaoxian; Chung, Hau Yin; Li, Yaolan - BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Volume: 411 Issue: 2 Pages: 342-347 DOI : http://dx.doi.org/: 10.1016/j.bbrc.2011.06.144 Published: JUL 29 2011
10. Antiviral dicaffeoyl derivatives from Elephantopus scaber
Geng, Hua-Wei; Zhang, Xiao-Li; Wang, Guo-Cai; et al. - JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH Volume: 13 Issue: 7 Pages: 665-669 DOI : http://dx.doi.org/: 10.1080/10286020.2011.584310 Published: 2011
11. Elephantopus scaber Inhibits Lipopolysaccharide-Induced Liver Injury by Suppression of Signaling Pathways in Rats
Hung, Hsiao-Fang; Hou, Chien-Wei; Chen, Yi-Ling; et al. - AMERICAN JOURNAL OF CHINESE MEDICINE Volume: 39 Issue: 4 Pages: 705-717 DOI : http://dx.doi.org/: 10.1142/S0192415X11009147 Published: 2011
12. Evaluation of Elephantopus scaber on the inhibition of chemical carcinogenesis and tumor development in mice
Geetha, B. S.; Latha, P. G.; Remani, P. - PHARMACEUTICAL BIOLOGY Volume: 48 Issue: 3 Pages: 342-348 DOI : http://dx.doi.org/: 10.3109/13880200903133845 Published: MAR 2010
13. Elephantopus scaber Linn.: From Ground to the Clay Pot
Alitheen, Noorjahan Banu; Keong, Yeap Swee; Yong, Ho Wan - Drug Plants I Book Series: Recent Progress in Medicinal Plants Volume: 27 Pages: 119-139 Published: 2010
14. Traditional practice, bioactivities and commercialization potential of Elephantopus scaber Linn.
Ho, Wan Yong; Ky, Huynh; Yeap, Swee Keong; et al. - JOURNAL OF MEDICINAL PLANTS RESEARCH Volume: 3 Issue: 13 Pages: 1212-1221 Published: DEC 2009
15. Antiproliferative Activities of Five Chinese Medicinal Herbs and Active Compounds in Elephantopus scaber
Su, Miaoxian; Wu, Xia; Chung, Hau Yin; et al. - NATURAL PRODUCT COMMUNICATIONS Volume: 4 Issue: 8 Pages: 1025-1030 Published: AUG 2009
16. A novel Steroid from Elephantopus scaber L. an Ethnomedicinal plant with antidiabetic activity
Daisy, P.; Jasmine, R.; Ignacimuthu, S.; et al. - PHYTOMEDICINE Volume: 16 Issue: 2-3 Pages: 252-257 DOI : http://dx.doi.org/: 10.1016/j.phymed.2008.06.001 Published: MAR 2009
17. A new elemanolide sesquiterpene lactone from Elephantopus scaber
Liang, Qiao-Li; Min, Zhi-Da; Tang, Yu-Ping - JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH Volume: 10 Issue: 5 Pages: 403-407 DOI : http://dx.doi.org/: 10.1080/10286020801966526 Published: 2008
18. [Structure modification on sesquiterpene lactones from Elephantopus scaber].
Liang, Qiao-li; Min, Zhi-da - Yao xue xue bao = Acta pharmaceutica Sinica Volume: 42 Issue: 11 Pages: 1159-61 Published: 2007-Nov
19. Structure modification on sesquiterpene lactones from Elephantopus scaber
Qiao-li, Liang; Zhi-da, Min - Yaoxue Xuebao Volume: 42 Issue: 11 Pages: 1159-1161 Published: NOV 2007
20. Genetic diversity and population structure in Elephantopus scaber (Asteraceae) from South China as revealed by ISSR markers
Wang, L.; Liu, J.; Zhang, W.; et al. - PLANT BIOSYSTEMS Volume: 140 Issue: 3 Pages: 273-279 DOI : http://dx.doi.org/: 10.1080/11263500600947699 Published: NOV 2006
21. Anti diarrheal activity of root extracts of Elephantopus scaber L
Vrushabendra Swamy, B. M.; Jayaveera, K. N.; Kumar, G. S.; et al. - PLANTA MEDICA Volume: 72 Issue: 11 Pages: 1067-1067 Meeting Abstract: P289 Published: SEP 2006
22. Antitumor activities of the four sesquiterpene lactones from Elephantopus scaber L.
Xu, G.; Liang, Q.; Gong, Z.; et al. - Experimental Oncology Volume: 28 Issue: 2 Pages: 106-109 Published: JUN 2006
23. Chemotypical variabiulity of leaf oils in Elephantopus scaber from 12 locations in China
Wang, L; Jian, SG; Nan, P; et al. - CHEMISTRY OF NATURAL COMPOUNDS Volume: 41 Issue: 5 Pages: 491-493 DOI : http://dx.doi.org/: 10.1007/s10600-005-0190-z Published: SEP-OCT 2005
24. Wound healing activity of the leaf extracts and deoxyelephantopin isolated from Elephantopus scaber Linn.
Singh, S. D. J.; Krishna, V.; Mankani, K. L.; et al. - Indian Journal of Pharmacology Volume: 37 Issue: 4 Pages: 238-242 Published: AUG 2005
25. A study of the antimicrobial activity of Elephantopus scaber
Avani, K.; Neeta, S. - Indian Journal of Pharmacology Volume: 37 Issue: 2 Pages: 126-127 Published: APR 05
26. Sesquiterpene lactones from Elephantopus scaber
Than, NN; Fotso, S; Sevvana, M; et al. - ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES Volume: 60 Issue: 2 Pages: 200-204 Published: FEB 2005
27. Chemical composition of the essential oil of Elephantopus scaber from Southern China
Wang, L; Jian, SG; Nan, P; et al. - ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES Volume: 59 Issue: 5-6 Pages: 327-329 Published: MAY-JUN 2004
28. ANTIBACTERIAL STUDIES ON LEAF EXTRACT OF ELEPHANTOPUS SCABER Linn.
Kumar, S Suresh; Perumal, P; Suresh, B - Ancient science of life Volume: 23 Issue: 3 Pages: 6-8 Published: 2004-Jan
29. Sesquiterpene lactones from Elephantopus scaber
Liang, QL; Da Min, Z - CHINESE CHEMICAL LETTERS Volume: 13 Issue: 4 Pages: 343-344 Published: APR 2002
30. Antitumour activity of Elephantopus scaber Linn against Dalton's ascitic lymphoma.
Rajkapoor, B.; Jayakar, B.; Anandan, R. - Indian Journal of Pharmaceutical Sciences Volume: 64 Issue: 1 Pages: 71-73 Published: January-February 2002
31. Hepatoprotection by Elephantopus scaber Linn. in CCl4-induced liver injury
Rajesh, M. G.; Latha, M. S. - Indian Journal of Physiology and Pharmacology Volume: 45 Issue: 4 Pages: 481-486 Published: October, 2001
32. Sesquiterpene lactones from Elephantopus scaber
But, PPH; Hon, PM; Cao, H; et al. - PHYTOCHEMISTRY Volume: 44 Issue: 1 Pages: 113-116 Published: JAN 1997
33. GUAIANOLIDE GLUCOSIDES FROM ELEPHANTOPUS-SCABER
HISHAM, A; PIETERS, L; CLAEYS, M; et al. - PLANTA MEDICA Volume: 58 Issue: 5 Pages: 474-475 DOI : http://dx.doi.org/: 10.1055/s-2006-961521 Published: OCT 1992
34. PRELIMINARY PHARMACOLOGICAL EVALUATION OF CRUDE WHOLE PLANT-EXTRACTS OF ELEPHANTOPUS-SCABER .1. INVIVO STUDIES
POLI, A; NICOLAU, M; SIMOES, CMO; et al. - JOURNAL OF ETHNOPHARMACOLOGY Volume: 37 Issue: 1 Pages: 71-76 DOI : http://dx.doi.org/: 10.1016/0378-8741(92)90005-C Published: AUG 1992
35. THE PHARMACOLOGICAL AND PATHOLOGICAL-STUDIES ON TAIWAN FOLK MEDICINE .6. THE EFFECTS OF ELEPHANTOPUS-SCABER SUBSP-OBLANCEOLATA, E-MOLLIS AND PSEUDOELEPHANTOPUS-SPICATUS
LIN, CC; YEN, MH; CHIU, HF - AMERICAN JOURNAL OF CHINESE MEDICINE Volume: 19 Issue: 1 Pages: 41-50 DOI : http://dx.doi.org/: 10.1142/S0192415X91000065 Published: 1991
36. A NEW CYTOTOXIC GUAIANOLIDE GLUCOSIDE FROM ELEPHANTOPUS-SCABER
HISHAM A; PIETERS L A C; DOMMISSE R; et al. - Planta Medica Volume: 56 Issue: 6 Pages: 542 DOI : http://dx.doi.org/: 10.1055/s-2006-961113 Published: 1990
37. PARTIAL-PURIFICATION AND CHARACTERIZATION OF STARCH PHOSPHORYLASE FROM CABBAGE (ELEPHANTOPUS-SCABAR) LEAVES
KUMAR, A - INDIAN JOURNAL OF PLANT PHYSIOLOGY Volume: 27 Issue: 2 Pages: 209-213 Published: 1984
38. A NEW SESQUITERPENE LACTONE FROM ELEPHANTOPUS-SCABER
DESILVA, LB; HERATH, WHMW; JENNINGS, RC; et al. - PHYTOCHEMISTRY Volume: 21 Issue: 5 Pages: 1173-1175 Published: 1982
39. A NEW SESQUI TERPENE LACTONE FROM ELEPHANTOPUS-SCABER
DE SILVA L B; HERATH W H M W; JENNINGS R C; et al. - Phytochemistry (Oxford) Volume: 21 Issue: 5 Pages: 1173-1175 Published: 1982
40. A NEW SESQUI TERPENE LACTONE FROM ELEPHANTOPUS-SCABER
DE SILVA L B; HERATH W H M W; JENNINGS R C; et al. - Phytochemistry (Oxford) Volume: 21 Issue: 5 Pages: 1173-1175 Published: 1982
41. ISODEOXYELEPHANTOPIN, A NEW GERMACRANEDIOLIDE FROM ELEPHANTOPUS-SCABER LINN
GOVINDAC.TR; VISWANAT.N; FUHRER, H - INDIAN JOURNAL OF CHEMISTRY Volume: 10 Issue: 3 Pages: 272-& Published: 1972
42. DEOXYELEPHANTOPIN, A NEW SESQUITERPENE FROM ELEPHANTOPUS-SCABER LINN
GOVINDAC.TR; SIDHAYE, AR; VISWANAT.N - INDIAN JOURNAL OF CHEMISTRY Volume: 8 Issue: 8 Pages: 762-& Published: 1970
43. CONSTITUENTS OF ELEPHANTOPUS SCABER (COMPOSITAE)
SIM, KY; LEE, HT - PHYTOCHEMISTRY Volume: 8 Issue: 5 Pages: 933-& DOI : http://dx.doi.org/: 10.1016/S0031-9422(00)85888-4
44. ON OCCURRENCE OF CHROMOSOMAL VARIABILITY IN SOMATIC CELLS OF ELEPHANTOPUS SCABER LINN
AYYANGAR, KR; SAMPATHK.R - CURRENT SCIENCE Volume: 36 Issue: 17 Pages: 470-& Published: 1967
45. CHEMICAL EXAMINATION OF ELEPHANTOPUS SCABER LINN
GHANIM, A; KIDWAI, AR; ZAMAN, A - INDIAN JOURNAL OF CHEMISTRY Volume: 1 Issue: 7 Pages: 320-& Published: 1963
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