Dysoxylum binectariferum, Dysoxylum gotadhora

Dysoxylum gotadhora (Buch.-Ham.) Mabb.
Family: Meliaceae

Synonym: Dysoxylum binectariferum (Roxb.) Hook.f. ex Bedd., Alliaria golodhara Kuntze , Amoora ficiformis Wight , Dysoxylum binectariferum (Roxb.) Hook.f. ex Bedd. , Dysoxylum binectarifolium C.DC. , Dysoxylum ficiforme (Wight) Gamble , Dysoxylum grandifolium H.L.Li [Illegitimate] , Dysoxylum reticulatum King , Epicharis gotadhora M.Roem. , Guarea amaris Buch.-Ham. , Guarea binectarifera Roxb. , Guarea gotadhora Buch.-Ham. , Dysoxylum binectariferum var. coriaceum C.DC. , Dysoxylum binectariferum var. punctulatum C.DC. , Dysoxylum binectariferum var. pyyriforme Thwaites ex Trimen, 

Siddha/Tamil: Agunivagil, Cembil.
Folk:  Lassuni (West Bengal).
Action: Fruit—anti-inflammatory, diuretic, CNS depressant.

The bark from mature trees contain 15% tannin and that from young trees 10%. EtOH (50%) extract of fruit—antiinflammatory, diuretic and CNS depressant.

The fruit contains a tetranortriterpenoid, dysobinin, a potential CNS depressant and inflammation inhibitor. The stem bark contains an alkaloid, rohitukine, which exhibited anti-inflammatory and immunomodulatory property [Indian Medicinal Plants An Illustrated Dictionary]

12 Published articles of Dysoxylum binectariferum
1.     Fusarium proliferatum, an endophytic fungus from Dysoxylum binectariferum Hook.f, produces rohitukine, a chromane alkaloid possessing anti-cancer activity
Kumara, Patel Mohana; Zuehlke, Sebastian; Priti, Vaidyanathan; et al. - ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY  Volume: 101   Issue: 2   Pages: 323-329   DOI:  http://dx.doi.org/10.1007/s10482-011-9638-2   Published: FEB 2012
2.     Fusarium proliferatum, an endophytic fungus from Dysoxylum binectariferum Hook.f, produces rohitukine, a chromane alkaloid possessing anti-cancer activity.
Mohana Kumara, Patel; Zuehlke, Sebastian; Priti, Vaidyanathan; et al. - Antonie van Leeuwenhoek  Volume: 101   Issue: 2   Pages: 323-9   DOI:  http://dx.doi.org/10.1007/s10482-011-9638-2   Published: 2012-Feb (Epub 2011 Sep 04)
3.     Dysoxylum binectariferum Hook.f (Meliaceae), a rich source of rohitukine
Mohanakumara, Patel; Sreejayan, Nambiar; Priti, Vaidayanathan; et al. - FITOTERAPIA  Volume: 81   Issue: 2   Pages: 145-148   DOI:  http://dx.doi.org/10.1016/j.fitote.2009.08.010   Published: MAR 2010
4.     Contraceptive and hormonal properties of the stem bark of Dysoxylum binectariferum in rat and docking analysis of rohitukine, the alkaloid isolated from active chloroform soluble fraction
Keshri, Govind; Oberoi, Ravi Mohan; Lakshmi, Vijai; et al. - CONTRACEPTION  Volume: 76   Issue: 5   Pages: 400-407   DOI:  http://dx.doi.org/10.1016/j.contraception.2007.07.009   Published: NOV 2007
5.     In vitro and in vivo leishmanicidal activity of Dysoxylum binectariferum and its fractions against Leishmania donovani
Lakshmi, V.; Pandey, K.; Kapil, A.; et al. - PHYTOMEDICINE  Volume: 14   Issue: 1   Pages: 36-42   DOI:  http://dx.doi.org/10.1016/j.phymed.2005.10.002   Published: 2007
6.     A new alkaloid from Dysoxylum binectariferum
Yang, DH; Cai, SQ; Zhao, YY; et al. - JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH  Volume: 6   Issue: 3   Pages: 233-236   DOI: http://dx.doi.org/10.1080/10286020310001608930   Published: SEP 2004
7.     Fatty acid composition and physico-chemical properties of Dysoxylum binectariferum seed coat oil
Parcha, Versha; Gahlot, Manoj; Rawat, M. S. M. - Indian Forester  Volume: 129   Issue: 11   Pages: 1395-1398   Published: November 2003
8.     IMMUNOPHARMACOLOGICAL POTENTIAL OF ROHITUKINE - A NOVEL COMPOUND ISOLATED FROM THE PLANT DYSOXYLUM-BINECTARIFERUM
LAKDAWALA, AD; SHIROLE, MV; MANDREKAR, SS; et al. - ASIA PACIFIC JOURNAL OF PHARMACOLOGY  Volume: 3   Issue: 2   Pages: 91-98   Published: JUN 1988
9.     AN ANTIINFLAMMATORY CUM IMMUNOMODULATORY PIPERIDINYLBENZOPYRANONE FROM DYSOXYLUM-BINECTARIFERUM - ISOLATION, STRUCTURE AND TOTAL SYNTHESIS
NAIK, RG; KATTIGE, SL; BHAT, SV; et al. - TETRAHEDRON  Volume: 44   Issue: 7   Pages: 2081-2086   DOI:  http://dx.doi.org/10.1016/S0040-4020(01)90352-7   Published: 1988
10.     CHEMICAL INVESTIGATION ON DYSOXYLUM-BINECTARIFERUM SEEDS
SINGH R P; JAIN P P; SURI R K - Indian Journal of Physical and Natural Sciences  Volume: 2   Issue: 1   Pages: 50-51   Published: 1982
11.     DYSOBININ, A NEW TETRANORTRITERPENE FROM DYSOXYLUM-BINECTARIFERUM
SINGH, S; GARG, HS; KHANNA, NM - PHYTOCHEMISTRY  Volume: 15   Issue: 12   Pages: 2001-2002   DOI:  http://dx.doi.org/10.1016/S0031-9422(00)88877-9   Published: 1976
12.     Note on the resistance of the timber, Dysoxylum binectariferum, to marine wood-boring mollusc, Marbesia striata Linn.
Nagabhushanam, R. - Science & Culture  Volume: 29   Pages: 461-462   Published: 1963