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Thursday, December 12, 2013

Aconitum heterophyllum, Ativisha, Atis, adivitaiyam


Aconitum heterophyllum Wall. ex Royle
Family: Ranunculaceae

Synonyms: Aconitum atees Royle, Aconitum cordatum Royle, Aconitum heterophyllumvar. roylei L.B.Chaudhary & R.R.Rao, Aconitum ovatum Lindl., Aconitum petiolare Royle ex Stapf
Assamese: Aatich
Bengali: Ataicha
English: Atis Root
Gujrati: Ativishni Kali, Ativikhani Kali
Hindi: arand, ateicha, atis, atvika
Kannada: Ativisha, Athihage, athibaje, athivisha
Kashmiri: Kath
Malayalam: Atividayam, Ativitayam
Marathi: Ativisha,  atavish, athivish
Nepali: Atis, bikh
Oriya: Atushi
Punjabi: Atisa, Atees
Sanskrit: amrita, aruna, ataicha, atisaraghni, ativisa
Tamil: adhividayam, adivitaiyam, akuculapu
Telugu: Ativasa
Urdu: atees, atis shirin, beesh

Description: Roots, ovoid-conical, tapering downwards to a print, 2.0-7.5 cm long, 0.4-1.6 cm or more thick at its upper extremity, gradually decreasing in thickness towards tapering end, externally light ash-grey, white or grey-brown, while internally starch white, external surface wrinkled marked with scars of fallen rootlet and with a rosette of scaly rudimentary leaves on top: fracture, short, starchy, showing uniform white surface, marked towards centre by 4-7 concentrically arranged yellowish-brown dots, corresponding to end of fibrovascular bundles traversing root longitudinally taste, bitter with no tingling sensation.
Uses: krimiroga, Jvara, Kasa, Chardi, Amaatisara [API, Pt-I, Vol-I]

Often regarded as nonpoisosnous, antiperiodic, antiinflammatory, astringent (used in cough, diarrhoea, dyspepsia), tonic (used after fevers), febrifuge, antispasmodic (used in irritability of stomach and abdominal pains). [Indian Medicinal Plants An Illustrated Dictionary]

Antipyretic, antiperiodic, aphrodisiac, astringent tonic. Used in diarrhoea, indigestion, cough troubles during dentition in children.[Advances in Medicinal Plants]

49 Published articles of Aconitum heterophyllum
1.    nrDNA ITS sequence based SCAR marker to authenticate Aconitum heterophyllum and Cyperus rotundus in Ayurvedic raw drug source and prepared herbal products.
Seethapathy, G. S.; Balasubramani, S. P.; Padma Venkatasubramanian - Food Chemistry  Volume: 145   Pages: 1015-1020   DOI: http://dx.doi.org/10.1016/j.foodchem.2013.09.027   Published: 2014

2.    Protein changes during ethanol induced seed germination in Aconitum heterophyllum
Rana, Bindu; Sreenivasulu, Yelam - PLANT SCIENCE  Volume: 198   Pages: 27-38   DOI: http://dx.doi.org/10.1016/j.plantsci.2012.09.013   Published: JAN 2013

3.    Hypolipidemic effect of methanol fraction of Aconitum heterophyllum wall ex Royle and the mechanism of action in diet-induced obese rats.
Subash, A. K.; Anu Augustine - Journal of Advanced Pharmaceutical Technology and Research (JAPTR)  Volume: 3   Issue: 4   Pages: 224-228   Published: 2012

4.    Physicochemical standardization and evaluation of in-vitro antioxidant activity of Aconitum heterophyllum Wall.
Prasad, S. K.; Kumar, R.; Patel, D. K.; et al. - Asian Pacific Journal of Tropical Biomedicine  Issue: Suppl. 2   Pages: S526-S531   Published: 2012

5.    Optimization of conditions for in vitro seed germination and shoot multiplication of Aconitum heterophyllum Wall.
Priyanka Solanki; Priyanka Siwach - International Journal of Medicinal and Aromatic Plants  Volume: 2   Issue: 3   Pages: 481-487   Published: 2012

6.    Potential of herbarium records to sequence phenological pattern: a case study of Aconitum heterophyllum in the Himalaya
Gaira, Kailash S.; Dhar, Uppeandra; Belwal, O. K. - BIODIVERSITY AND CONSERVATION  Volume: 20   Issue: 10   Pages: 2201-2210   DOI: http://dx.doi.org/10.1007/s10531-011-0082-4   Published: SEP 2011

7.    Quantitative determination of aconitine in Aconitum chasmanthum and Aconitum heterophyllum from Kashmir Himalayas using HPLC.
Neelofar Jabeen; Shakeel-u-Rehman; Bhat, K. A.; et al. - Journal of Pharmacy Research  Volume: 4   Issue: 8   Pages: 2471-2473   Published: 2011

8.    Influence of pre-sowing treatments on in vitro seed germination of ativisha ( Aconitum heterophyllum Wall) of Uttarakhand.
Nidhi Srivastava; Vikas Sharma; Dobriyal, A. K.; et al. - Biotechnology  Volume: 10   Issue: 2   Pages: 215-219   Published: 2011

9.    In vitro antimicrobial activity of aerial parts extracts of Aconitum heterophyllum Wall. ex Royle.
Nidhi Srivastava; Vikas Sharma; Kriti Saraf; et al. - Indian Journal of Natural Products and Resources  Volume: 2   Issue: 4   Pages: 504-507   Published: 2011

10.    A note on the floral morphology of Aconitum heterophyllum Wall. (Ranunculaceae) - an important temperate medicinal plant.
Raina, R.; Rajesh Chauhan; Rekha Naithani - Open Access Journal of Medicinal and Aromatic Plants (OAJMAP)  Volume: 2   Issue: 2   Pages: 1-4   Published: 2011

11.    Anti-inflammatory activity of Aconitum heterophyllum on cotton pellet-induced granuloma in rats
Verma, Santosh; Ojha, Shreesh; Raish, Mohammad - JOURNAL OF MEDICINAL PLANTS RESEARCH  Volume: 4   Issue: 15   Pages: 1566-1569   Published: AUG 4 2010

12.    Polyphenolics free DNA isolation from different types of tissues of Aconitum heterophyllum wall-endangered medicinal species.
Nidhi Srivastava; Vikas Sharma; Barkha Kamal; et al. - Journal of Plant Sciences  Volume: 5   Issue: 4   Pages: 414-419   DOI: http://dx.doi.org/10.3923/jps.2010.414.419   Published: 2010

13.    Effect of storage containers on seed germination and viability in Aconitum heterophyllum and Podophyllum hexandrum - endangered medicinal plants species of Himalayan region.
Verma, N. K.; Verma, A. K.; Dharminder Kumar - Biological Forum  Volume: 1   Issue: 1   Pages: 8-11   Published: 2009

14.    New diterpenoid alkaloids from Aconitum heterophyllum Wall: Selective butyrylcholinestrase inhibitors
Nisar, Muhammad; Obaidullah; Ahmad, Manzoor; et al. - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY  Volume: 24   Issue: 1   Pages: 47-51   Article Number: PII 794859850   DOI: http://dx.doi.org/10.1080/14756360801906202   Published: 2009

15.    Floral Biology of Aconitum heterophyllum Wall.: A Critically Endangered Alpine Medicinal Plant of Himalaya, India
Nautiyal, Bhagwati P.; Nautiyal, Mohan C.; Khanduri, Vinod P.; et al. - TURKISH JOURNAL OF BOTANY  Volume: 33   Issue: 1   Pages: 13-20   Published: 2009

16.    ETHANOL INDUCED SEED GERMINATION IN ACONITUM HETEROPHYLLUM WALL.: AN ENDANGERED MEDICINAL HERB OF THE NORTH-WEST HIMALAYAS
Sreenivasulu, Yelam; Chanda, Sanjoy K.; Ahuja, Paramvir Singh - Indian Journal of Plant Physiology  Volume: 13   Issue: 2   Pages: 159-165   Published: APR-JUN 2008

17.    Norditerpenoid alkaloids from the roots of Aconitum heterophyllum Wall with antibacterial activity
Ahmad, Manzoor; Ahmad, Waqar; Ahmad, Mansoor; et al. - JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY  Volume: 23   Issue: 6   Pages: 1018-1022   DOI: http://dx.doi.org/10.1080/14756360701810140   Published: 2008

18.    Aconitine alkaloids from tubers of Aconitum heterophyllum and A-balfourii: Critically endangered medicinal herbs of Indian Central Himalaya
Pandey, H.; Nandi, S. K.; Kumar, A.; et al. - NATIONAL ACADEMY SCIENCE LETTERS-INDIA  Volume: 31   Issue: 3-4   Pages: 89-93   Published: 2008

19.    Vegetative propagation of Aconitum heterophyllum wall ex Royle.
Joshi, Kapil Kumar - Indian Forester  Volume: 132   Issue: 8   Pages: 1064-1065   Published: AUG 2006

20.    Callus induction and organogenesis from explants of Aconitum heterophyllum-medicinal plant.
Neelofar Jabeen; Shawl, A. S.; Dar, G. H.; et al. - Biotechnology  Volume: 5   Issue: 3   Pages: 287-291   Published: 2006

21.    Ex situ conservation of Aconitum heterophyllum Wall. - an endangered medicinal plant of the Himalaya through mass propagation and its effect on growth and alkaloid content
Pandey, Subedar; Kushwaha, Rekha; Prakash, Om; et al. - Plant Genetic Resources Characterization and Utilization  Volume: 3   Issue: 2   Pages: 127-135   DOI: http://dx.doi.org/10.1079/PGR200570   Published: AUG 2005

22.    Cultivation and conservation of Aconitum heterophyllum: a critically endangered medicinal herb of the Northwest Himalayas.
Beigh, S. Y.; Nawchoo, I. A.; Muhammad Iqbal - Journal of Herbs, Spices & Medicinal Plants  Volume: 11   Issue: 4   Pages: 47-56   Published: 2005

23.    Methods of sustainable harvesting and value addition for economic uplift and biodiversity conservation series 26 - harvesting of economically important medicinal plant species:, Aconitum heterophyllum, Andrographis paniculata, Spilanthes acmella, Taxus baccata, Withania somnifera.
Alka Shiva - MFP News  Volume: 15   Issue: 1   Pages: 12-14   Published: 2005

24.    Polypeptide patterns and isoenzymes in different populations of Aconitum heterophyllum Wall ex Royle, from Garhwal Himalaya.
Bahuguna, Raman; Purohit, M. C.; Nautiyal, B. P.; et al. - Physiology and Molecular Biology of Plants  Volume: 9   Issue: 1   Pages: 95-100   Published: January 2003

25.    Seed germination and seedling survival of Aconitum heterophyllum, an endangered medicinal plant of the North-West Himalaya
Beigh, Showkat Yousuf; Iqbal, Muhammad; Nawchoo, Irshad A. - Indian Journal of Plant Physiology  Volume: 7   Issue: 2   Pages: 109-113   Published: April-June, 2002

26.    Seed germination and seedling survival of Aconitum heterophyllum, an endangered medicinal plant of the North-West Himalaya
Beigh, Showkat Yousuf; Iqbal, Muhammad; Nawchoo, Irshad A. - Indian Journal of Plant Physiology  Volume: 7   Issue: 2   Pages: 109-113   Published: April-June, 2002

27.    Effect of gibberellic acid on germination of Aconitum heterophyllum L
Singh, Virendra; Nayyar, H.; Uppal, Rajesh; et al. - Seed Research (New Delhi)  Volume: 28   Issue: 1   Pages: 85-86   Published: June, 2000

28.    Impact of cultivation on active constituents of the medicinal plants Podophyllum hexandrum and Aconitum heterophyllum in Sikkim.
Pankaj Prasad - Plant Genetic Resources Newsletter  Issue: 124   Pages: 33-35   Published: 2000

29.    Chemical stimulation of seed germination in Aconitum heterophyllum Wall. and A. balfourii Stapf.: Important Himalayan species of medicinal value
Pandey, H.; Nandi, S. K.; Nadeem, M.; et al. - Seed Science and Technology  Volume: 28   Issue: 1   Pages: 39-48   Published: 2000

30.    Chemical stimulation of seed germination in Aconitum heterophyllum Wall. and A-balfourii Stapf.: Important Himalayan species of medicinal value
Pandey, K; Nandi, SK; Nadeem, M; et al. - SEED SCIENCE AND TECHNOLOGY  Volume: 28   Issue: 1   Pages: 39-48   Published: 2000

31.    Enhancement of seed germination of Podophyllum hexandrum Royle and Aconitum heterophyllum Wall by different treatments.
Pankaj Prasad - Journal of Hill Research  Volume: 12   Issue: 2   Pages: 102-106   Published: 1999

32.    Production of hairy roots in Aconitum heterophyllum wall. using Agrobacterium rhizogenes
Giri, A; Banerjee, S; Ahuja, PS; et al. - IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-PLANT  Volume: 33   Issue: 4   Pages: 280-284   Published: OCT-DEC 1997

33.    Vulnerable and threatened plants of economic value: Aconitum heterophyllum (Atis). Family: Ranunculaceae.
Jain, A. - MFP News  Volume: 6   Issue: 1   Pages: 12   Published: 1996

34.    SOMATIC EMBRYOGENESIS AND PLANT-REGENERATION FROM CALLUS-CULTURES OF ACONITUM-HETEROPHYLLUM WALL
GIRI, A; AHUJA, PS; KUMAR, PVA - PLANT CELL TISSUE AND ORGAN CULTURE  Volume: 32   Issue: 2   Pages: 213-218   DOI: http://dx.doi.org/10.1007/BF00029845   Published: FEB 1993

35.    ATISENOL, A NEW ENT-ATISENE DITERPENOID LACTONE FROM ACONITUM-HETEROPHYLLUM
PELLETIER, SW; ATEYA, AMM; FINERMOORE, J; et al. - JOURNAL OF NATURAL PRODUCTS  Volume: 45   Issue: 6   Pages: 779-781   DOI: http://dx.doi.org/10.1021/np50024a028   Published: 1982

36.    C-13 NUCLEAR MAGNETIC-RESONANCE SPECTROSCOPY OF ATISINE AND VEATCHINE-TYPE C-20-DITERPENOID ALKALOIDS FROM ACONITUM AND GARRYA SPECIES
MODY, NV; PELLETIER, SW - TETRAHEDRON  Volume: 34   Issue: 16   Pages: 2421-2431   DOI: http://dx.doi.org/10.1016/0040-4020(78)88367-7   Published: 1978

37.    PHARMACOGNOSY OF ROOT OF CHAEROPHYLLUM-VILLOSUM-D AN ADULTERANT OF ACONITUM-HETEROPHYLLUM-D
SHARMA B M; SINGH P; ATAL C K - Journal of Research in Indian Medicine  Volume: 4   Issue: 1   Pages: 68-72   Published: 1969

38.    ALKALOIDS OF ACONITUM HETEROPHYLLUM WALL - ISOLATION AND CHARACTERIZATION
PELLETIE.SW; ANEJA, R; GOPINATH, KW - PHYTOCHEMISTRY  Volume: 7   Issue: 4   Pages: 625-&   DOI: http://dx.doi.org/10.1016/S0031-9422(00)88238-2   Published: 1968

39.    The alkaloids of Aconitum heterophyllum Wall.: isolation and characterization.
PELLETIER, S. W.; ANEJA, R.; GOPINATH, K. W. - Phytochemistry  Volume: 7   Pages: 625-35   Published: 1968

40.    The diterpene alkaloids: Three new diterpene lactone alkaloids from Aconitum heterophyllum Wall
PELLETIER, S. W.; ANEJA, R. - TETRAHEDRON LETT  Volume: 6   Pages: 557-562   Published: 1967

41.    DITERPENE ALKALOIDS . 3 NEW DITERPENE LACTONE ALKALOIDS FROM ACONITUM HETEROPHYLLUM WALL
PELLETIE.SW; ANEJA, R - TETRAHEDRON LETTERS  Issue: 6   Pages: 557-&   Published: 1967

42.    SOME CHEMISTRY OF HETERATISINE
EDWARDS, OE; FERRARI, C - CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE  Volume: 42   Issue: 1   Pages: 172-&   DOI: http://dx.doi.org/10.1139/v64-027   Published: 1964

43.    ATIDINE, A NEW DITERPENE ALKALOID FROM ACONITUM-HETEROPHYLLUM
PELLETIER, SW - CHEMISTRY & INDUSTRY  Issue: 38   Pages: 1016-1017   Published: 1956

44.    The aconite alkaloids XII. Benzoyl heteratisine, a new alkaloid from aconitum heterophyllum
Jacobs, WA; Craig, LC - JOURNAL OF BIOLOGICAL CHEMISTRY  Volume: 147   Issue: 3   Pages: 0571-0572   Published: MAR 1943

45.    The aconite alkaloids XI. The action of methyl alcoholic sodium hydroxide on atisine. Isoatisine and dihydroatisine
Jacobs, WA; Craig, LC - JOURNAL OF BIOLOGICAL CHEMISTRY  Volume: 147   Issue: 3   Pages: 0567-0569   Published: MAR 1943

46.    The aconite alkaloids IX. The isolation of two new alkaloids from Aconitum heterophyllum, heteratisine and hetisine
Jacobs, WA; Craig, LC - JOURNAL OF BIOLOGICAL CHEMISTRY  Volume: 143   Issue: 3   Pages: 605-609   Published: MAY 1942

47.    The aconite alkaloids VIII. On atisine
Jacobs, WA; Craig, LC - JOURNAL OF BIOLOGICAL CHEMISTRY  Volume: 143   Issue: 3   Pages: 589-603   Published: MAY 1942

48.    Some physiological effects of atisine, alkaloid of Aconitum heterophyllum Wallich
Raymond-Hamet - COMPTES RENDUS DES SEANCES DE LA SOCIETE DE BIOLOGIE ET DE SES FILIALES  Volume: 128   Pages: 479-482   Part: 2   Published: 1938

49.    Atisine of Aconitum heterophyllum Wall and anthorine of Aconitum anthora L
Goris, A - COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES  Volume: 205   Pages: 1007-1009   Published: 1937

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