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Monday, December 1, 2014

Tinospora sinensis, gilo, Kattu amirthu


Tinospora sinensis (Lour.) Merr.
Family: Menispermaceae
Synonyms: Campylus sinensis Lour., Cocculus tomentosus Colebr., Menispermum cordifolium Willd., Menispermum malabaricum Lam., Menispermum tomentosum (Colebr.) Roxb., Tinospora cordifolia (Willd.) Miers, Tinospora malabarica (Lam.) Hook. f. & Thomson, Tinospora tomentosa (Colebr.) Hook. f. & Thomson
  • Common name: Malabar Gulbel, Chinese tinospora
  • Assamese: hoguni-lota
  • Chinese: 中华青牛胆 
  • Hindi: गिलोय giloy, गुलंचा gulancha, gurch
  • Kannada: Sudarsana balli
  • Malayalam: Pee-amerdu, Kattu amirthu
  • Marathi: gulvel, vhadli-amrutvel
  • Nepali: गुरुज Guruj
  • Sanskrit: Vatsadani, Sudarsana, Amrta
  • Tamil: potchindil
  • Telugu: tippatega తిప్పతీగ,
Discription: Leaves 11-14 x 9-11 cm, broadly ovate, apex acuminate, base cordate, 5-7ribbed, scabrous above, densely white tomentose below. Male flowers 3-5 together, pedicelled; sepals 6 in 2 whorls, outer smaller, inner 2 x 1.5 mm, obovate; petals 6 smaller; stamens 6, free, anthers orbicular. Female flowers: sepals and petals similar to male flowers; carpels 3, stigma bilobed, staminodes 6, clavate. Drupe 8 mm long, 1 or 2 together, ovoid, red, glabrous.

Used in Ayurveda and Sidha. Tonic, immunostimulant, antiinflammatory, antiallergic, antimalarial, antidiabetic, hepatoprotective, nutrient, used for treating arthritis and chronic rheumatism, good revitalizer for old age diseases, increases appetite  and  digestion  for  elderly.  Stems  for  treating  bronchitis,  asthma,  piles,  ulcerated  wounds,  liver  complaints, chronic rheumatism and also as muscle relaxant; stem juice febrifuge. Leaf extract used as ear drop.

48 Published articles of Tinospora sinensis (Lour.) Merr.

1.    Comparative studies of the immunomodulatory activity of Tinospora cordifolia and Tinospora sinensis
Manjrekar, PN; Jolly, CI; Narayanan, S
FITOTERAPIA  Volume: 71   Issue: 3   Pages: 254-257   Published: JUN 2000

2.    Structure and absolute configuration of clerodane diterpene glycosides and a rearranged cadinane sesquiterpene glycoside from the stems of Tinospora sinensis
Li, Wei; Wei, Kun; Fu, Hongwei; et al.
JOURNAL OF NATURAL PRODUCTS  Volume: 70   Issue: 12   Pages: 1971-1976   Published: DEC 2007

3.    New lignan glucosides from the stems of Tinospora sinensis
Li, W; Koike, K; Liu, L; et al.
CHEMICAL & PHARMACEUTICAL BULLETIN  Volume: 52   Issue: 5   Pages: 638-640   Published: MAY 2004

4.    HPLC Estimation of berberine in Tinospora cordifolia and Tinospora sinensis
Srinivasan, G. V.; Unnikrishnan, K. P.; Shree, A. B. Rema; et al.
INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES  Volume: 70   Issue: 1   Pages: 96-U21   Published: JAN-FEB 2008

5.    STUDIES ON THE CONSTITUENTS OF TINOSPORA-SINENSIS .1. SEPARATION AND STRUCTURE OF THE NEW PHENOLIC GLYCOSIDE TINOSINEN
YONEMITSU, M; FUKUDA, N; KIMURA, T
PLANTA MEDICA  Volume: 59   Issue: 6   Pages: 552-553   Published: DEC 1993

6.    Evaluation of antileishmanial potential of Tinospora sinensis against experimental visceral leishmaniasis
Singh, Nasib; Kumar, Awanish; Gupta, Prasoon; et al.
PARASITOLOGY RESEARCH  Volume: 102   Issue: 3   Pages: 561-565   Published: FEB 2008

7.    STUDIES ON THE CONSTITUENTS OF THE STEMS OF TINOSPORA-SINENSIS .2. ISOLATION AND STRUCTURE ELUCIDATION OF 2 NEW DINORDITERPENE GLUCOSIDES, TINOSINESIDE-A AND TINOSINESIDE-B
YONEMITSU, M; FUKUDA, N; KIMURA, T; et al.
LIEBIGS ANNALEN  Issue: 2   Pages: 437-439   Published: FEB 1995

8.    Constituents of Tinospora sinensis and their antileishmanial activity against Leishmania donovani
Maurya, Rakesh; Gupta, Prasoon; Chand, Kailash; et al.
NATURAL PRODUCT RESEARCH  Volume: 23   Issue: 12   Pages: 1134-1143   Article Number: PII 913698490   Published: 2009

9.    Tinospora sinensis (Lour.) Merr. from Sickupara, Kolli Hills Forest, Namakkal District, Tamil Nadu
Udayan, P. S.; George, Satheesh; Tushar, K. V.; et al.
Zoos' Print Journal  Volume: 19   Issue: 9   Pages: 1622-1623   Published: September 2004

10.    中华青牛胆的化学成分研究
Chemical constituents from Tinospora sinensis
任艳丽; 唐前瑞; 张桢; et al.
REN Yanli; TANG Qianrui; ZHANG Zhen; et al.
天然产物研究与开发  Volume: 20   Issue: 2   Pages: 278-279,282   Article Number: 1001-6880(2008)20:2<278:zhqndd>2.0.TX;2-O   Published: 2008
Natural Product R & D  Volume: 20   Issue: 2   Pages: 278-279,282   Article Number: 1001-6880(2008)20:2<278:zhqndd>2.0.TX;2-O   Published: 2008

11.    NOTE ON MAGNIFICENT TINOSPORA-SINENSIS LOUR. MERRILL IN SACRED GROVES OF THE PUNE DISTRICT INDIA
UPADHYE A S; KUMBHOJKAR M S; VARTAK V D
Indian Forester  Volume: 113   Issue: 2   Pages: 154-157   Published: 1987

12.    A new dinorclerone diterpenoid glycoside from Tinospora sinensis
Dong, Lang-Ping; Chen, Chang-Xiang; Ni, Wei; et al.
NATURAL PRODUCT RESEARCH  Volume: 24   Issue: 1   Pages: 13-17   Published: 2010

13.    Do assorted approaches aid in estimation of uronic acids? Case studies on Tinospora sinensis polysaccharides
Kumar, Vineet; Nagar, Shipra; Tripathi, Y. C.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES  Volume: 70   Pages: 360-363   Published: SEP 2014

14.    Comparative immunomodulation potential of Tinospora cordifolia (Willd.) Miers ex Hook. F., Tinospora sinensis (Lour.) Merrill and Tinospora cordifolia growing on Azadirachta indica A. Juss.
Narkhede, A. N.; Jagtap, S. D.; Kasote, D. M.; et al.
INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY  Volume: 52   Issue: 8   Pages: 808-813   Published: AUG 2014

15.    Traditional Chinese medicine liquid used for skin whitening and removing toxin, increasing blood circulation, reducing pigmentation comprises Hibiscus leaf, Schefflera kwangsiensis, Fructus Coriandri and Tinospora sinensis
Patent Number: CN103877283-A
Patent Assignee: SHI W
Inventor(s): SHI W.

16.    Traditional Chinese medicine composition used for treating cough and asthma, includes Ephedra, elaeagnus leaves, licorice, Lagotis, radix astragali, Houttuynia cordata, Tinospora sinensis, dendrobe, loquat leaves, Aster, and sweet wormwood
Patent Number: CN103520514-A
Patent Assignee: SHI X
Inventor(s): SHI X; SUI X.

17.    Capsule contains white gentian, sandalwood, fructus Terminalia, myrobalan, emblic leafflower fruit, lime stone, Costus root, clove, Myristica fragrans, Tinospora sinensis, agilawood, gamuzhuer, Pegaeophyton scapiflorum and licorice
Patent Number: CN103638202-A
Patent Assignee: NINGXIA DUOWEI PHARM CO LTD
Inventor(s): WANG C; BAO R; YE X; et al.

18.    Traditional Chinese medicine useful for treating knee osteoarthritis, prepared using e.g. Vernonia volkameriifolia, Tinospora sinensis, parasitic Loranthus, towel gourd, rhizoma drynariae, Chinese dodder seed and fructus gardeniae
Patent Number: CN103720839-A
Patent Assignee: ZHANG L
Inventor(s): ZHANG L; LIU J; ZHUANG Y.

19.    Preparation of female medicinal granule used for improving young female complexion by providing Plumbago indica, Passiflora wilsonii leaf, Tinospora sinensis, water mint, Caesalpinia sappan and Arundina graminifolia leaves
Patent Number: CN103919139-A
Patent Assignee: XISHUANGBANNA FOXIN PHARM CO LTD
Inventor(s): ZHOU S.

20.    Acute hepatitis and jaundice due to Tinospora sinensis or Tinospora crispa
Wu, Ming-Ling; Deng, Jou-Fang; Yang, Chen-Yang
CLINICAL TOXICOLOGY  Volume: 51   Issue: 4   Pages: 268-269   Meeting Abstract: 31   Published: MAY 2013

21.    Comparative hepatoprotective potential of Tinospora cordifolia, Tinospora sinensis and Neem-guduchi.
Bhagyashri Nagarkar; Rohan Kulkarni; Prashant Bhondave; et al.
British Journal of Pharmaceutical Research  Volume: 3   Issue: 4   Pages: 906-916   Published: 2013

22.    Chinese medicine composition for treating e.g. acute chest pain, comprises Tinospora sinensis, earthworm, orange, Aucklandia radix, roasted semen, Vaccaria, Ligusticum wallichii rhizome, Litsea coreana, mint, borneol and musk
Patent Number: CN103223012-A
Patent Assignee: BU H
Inventor(s): BU H.

23.    Traditional Chinese external medicine useful for treating hyperosteogeny contains Angelica, Notopterygium, radix cyathulae, Eucommia bark, Tinospora sinensis, turmeric, Chinese teasel root, Asarum and rice vinegar
Patent Number: CN103127468-A
Patent Assignee: MENG B; MENG Y
Inventor(s): MENG B; MENG Y.

24.    Pill useful for e.g. strengthening bone, comprises corydalis tuber, Tinospora sinensis, rhizoma drynariae, Trogopterus dung, herba siegesbeckiae, radix millettiae speciosae, holly root, Eucommia and nidus vespae
Patent Number: CN102973661-A
Patent Assignee: JIANGSU DINGXIN ELECTRIC CO LTD
Inventor(s): ZHANG J.

25.    宽筋藤组织培养的初步研究
The Preliminary Study on Tissue Culture of Tinospora sinensis
陈加利; 杨琪; 林海叶; et al.
Chen Jiali; Yang Qi; Lin Haiye; et al.
中国农学通报  Volume: 28   Issue: 10   Pages: 219-224   Article Number: 1000-6850(2012)28:10<219:kjtzzp>2.0.TX;2-#   Published: 2012
Chinese Agricultural Science Bulletin  Volume: 28   Issue: 10   Pages: 219-224   Article Number: 1000-6850(2012)28:10<219:kjtzzp>2.0.TX;2-#   Published: 2012

26.    Traditional Chinese medicinal composition used for treating scapulohumeral periarthritis includes Tinospora sinensis, Flemingia philippinensis, siegesbeckia orientalis grass, Entada phaseoloides, Potaliaceae, and parasitic Loranthus
Patent Number: CN102552637-A; CN102552637-B
Patent Assignee: JIN L
Inventor(s): JIN L.

27.    Forming Tibetan medicine for treating pharyngitis involves mixing and grinding Tinospora sinensis Merr, Rubus phoenicolasius Tinospora, Phlomis younghusbandii, pterocephalus hookeri heck, Ajowan and licorice extract into fine powder
Patent Number: CN102614269-A; CN102614269-B
Patent Assignee: JIUMEI P
Inventor(s): JIUMEI P.

28.    A new compound, extractive comprising the compound and its preparing method and application
Patent Number: CN102600261-B; CN102600261-A
Patent Assignee: JIUMEIPENGCUO
Inventor(s): JIUMEIPENGCUO.

29.    Molecular identification of Tinospora sinensis by ITS2 sequence analysis.
Khanapurkar, R. S.; Paul Nilesh; Desai, D. M.; et al.
International Journal of Molecular Biology  Volume: 3   Issue: 2   Pages: 55-57   Published: 2012
   from Publisher

30.    Qingpeng plaster used for, e.g. easing pain, comprises Oxytropis, Asian rhubarb, Aconitum pendulum, denucleated myrobalan, fructus terminaliae billericae, emblic leafflower fruit, benzoin, Tinospora sinensis, musk, and additives
Patent Number: CN102038765-A; CN102038765-B
Patent Assignee: TIBET CHEEZHENG TIBETAN MEDICINE CO LTD
Inventor(s): CHEN L; LIU H; ZHANG Y; et al.

31.    Qingpeng liniment or lotion useful for preparing medicine for reducing swelling, contains whin, Asian rhubarb, Aconitum pendulum, denucleated myrobalan, fructus terminaliae billericae, benzoin, Tinospora sinensis and musk
Patent Number: CN102038766-A; CN102038766-B
Patent Assignee: TIBET CHEEZHENG TIBETAN MEDICINE CO LTD
Inventor(s): CHEN L; ZHANG P; ZHANG Y; et al.

32.    Traditional Chinese medicine drug, e.g. used for dissolving stasis, includes cortex acanthopanacis, safflower, rehmanniae, Chinese Angelica, radix achyranthis bidentatae, jasmine, herba lycopi, Drynaria rhizome, and Tinospora sinensis
Patent Number: CN102000203-A
Patent Assignee: JIANG M
Inventor(s): JIANG M.

33.    Qingpeng Tibetan medicine paste oral preparation used for relieving pain and reducing swelling, includes Oxytropis, rhubarb, Aconitum pendulum, denucleated myrobalan, Phyllanthus emblica, benzoin, Tinospora sinensis, and musk
Patent Number: CN102058687-A; CN102058687-B
Patent Assignee: TIBET CHEEZHENG TIBETAN MEDICINE CO LTD
Inventor(s): LI Z; CHEN L; ZHANG P; et al.

34.    Traditional Chinese medicine, e.g. used for treating diabetic limb necrosis or relaxing muscles and joints, comprises Tinospora sinensis, pseudoginseng, Chinese Angelica, and lucid Ganoderma
Patent Number: CN102018765-A
Patent Assignee: BEIJING LVYUANQIUZHENG TECHNOLOGY DEV CO
Inventor(s): LIU X.

35.    Composition used e.g. for treating gout, clearing away heat, detoxifying, removing swelling, and relieving pain, comprises alpine Codonopsis, Tinospora sinensis, costus root, rhizoma nardostachyos, and Turkey corn
Patent Number: CN102000159-A; CN102000159-B
Patent Assignee: UNIV XIAN JIAOTONG; UNIV TIBET
Inventor(s): LIU Z; ZHANG L; NIU X; et al.

36.    Luoduiduoji granule formulation used for treating gout, is composed of additives and active material alpine Codonopsis, Tinospora sinensis, costustoot, northland Corydalis and rhizoma nardostachyos
Patent Number: CN102000160-A; CN102000160-B
Patent Assignee: UNIV XIAN JIAOTONG; UNIV TIBET
Inventor(s): LIU Z; ZHANG L; NIU X; et al.

37.    Tinospora sinensis (Lour) Merr. (Menispermaceae) a new record for Madhya Pradesh state red listed medicinal plants.
Shaikh Mujaffar; Mehra, S. S.
Journal of Tropical Forestry  Volume: 27   Issue: 2   Pages: 61-63   Published: 2011

38.    Overcoated medicinal bag useful for treating lumbosacral pain, contains teasel root, Eucommia ulmoides, Tinospora sinensis, radix achyranthis bidentatae, Angelica sinensis, root of red-rooted Salvia, and Notopterygium root
Patent Number: CN102018935-A
Patent Assignee: WANG W
Inventor(s): WANG W.

39.    Composition useful for treating gout, comprises e.g. Schizonepeta, Cassia twig, caulis piperis futokadsurae, Toddalia asiatica root, Tinospora sinensis, Cassytha filiformis herb, Desmodium, Poria cocos and Curcuma zedoaria
Patent Number: CN102240378-A
Patent Assignee: ZHANG J
Inventor(s): ZHANG J.

40.    Monitoring of Nine Trace Elements in Chinese Herbal Medicine Tinospora sinensis (Lour.) Merr by ICP-MS
Xu, Fang; Rui Yu-Kui; Wei, Tianxing
ASIAN JOURNAL OF CHEMISTRY  Volume: 22   Issue: 9   Pages: 7429-7431   Published: SEP-OCT 2010

41.    ANTILEISHMANIAL AGENTS FROM TINOSPORA SINENSIS
Chand, Kailash; Akanksha; Singh, Nasib; et al.
MEDICINAL CHEMISTRY RESEARCH  Volume: 19   Supplement: 1   Pages: S74-S75   Published: FEB 2010

42.    Evaluation of antioxidant potential of Tinospora cordifolia and Tinospora sinensis.
Sanjay Jain; Bhumika Sherlekar; Rakesh Barik
International Journal of Pharmaceutical Sciences and Research (IJPSR)  Volume: 1   Issue: 11   Pages: 122-128   Published: 2010

43.    Traditional Chinese medicine, useful for treating pain in waist and lower extremities, comprises e.g. Eucommia, Tinospora sinensis, Saposhnikovia divaricata, Angelica sinensis, root of red-rooted Salvia, teasel root, and Notopterygium root
Patent Number: CN101879296-A
Patent Assignee: SHI C
Inventor(s): SHI C.

44.    Preparation of Qingpeng paste by mixing Qingpeng paste, thickening agent, and extract of gorse, Asia rhubarb, Aconitum uncinatum, myrobalan, fructus terminaliae billericae, orange oil, benzoin, Tinospora sinensis and water
Patent Number: CN101491600-A
Patent Assignee: GANSU QIZHENG TIBETAN MEDICINE CO LTD
Inventor(s): CHEN L; HE G; LIU H; et al.

45.    Hypoglycemic activity of Tinospora sinensis (Linn) leaves.
Pimpriker, B. R.; Patil, V. V.; SinthalKumar, K.; et al.
Journal of Pharmacy Research  Volume: 2   Issue: 4   Pages: 729-730   Published: 2009

46.    中华青牛胆扦插繁育试验研究
Experimental Study on Cutting Propagation of Tinospora sinensis (Lour.) Merr.
兰玲; 李融兴
LAN Ling
安徽农业科学  Volume: 36   Issue: 34   Pages: 15032-15033   Article Number: 0517-6611(2008)36:34<15032:zhqndq>2.0.TX;2-N   Published: 2008
Journal of Anhui Agricultural Sciences  Volume: 36   Issue: 34   Pages: 15032-15033   Article Number: 0517-6611(2008)36:34<15032:zhqndq>2.0.TX;2-N   Published: 2008

47.    Tinospora sinensis (Lour.) Merr. (Menispermaceae) - A hitherto unreported red listed medicinal plant from Tamil Nadu State
Sankar, R. Vijaya; Ravikumar, K.; Ravichandran, P.
Indian Forester  Volume: 130   Issue: 7   Pages: 731-734   Published: July 2004

48.    Contribution to the wood anatomy of tinospora sinensis (lour) merrill in relation with T.cordifolia miers.
Bonde, S D; Upaehye, A S
Ancient science of life  Volume: 9   Issue: 2   Pages: 80-5   Published: 1989-Oct

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