Family: Asteraceae
- English: Toothache Plant
- Chinese: 金鈕扣
- Czech: Plamatka
- Danish: Parakarse
- Dutch: Huzarenknoop
- Estonian: Harilik nööpkakar
- Finnish: Parakrassi
- French: Créosote
- German: Parakresse
- Hindi: Pipulka
- Hungarian: Abécefű
- Indonesian: Jotang
- Italian: Spilante
- Japanese: キバナオランダセンニチ
- Kannada: Hemmugalu
- Korean: 파라크레스
- Malay: pokok getang
- Malayalam: പല്ലുവേദനച്ചെടി
- Marati: अक्कलकारा
- Nepali: अकर
- Portuguese: Agrião do Brasil
- Russian: Спилантес
- Sanskrit: Sarahattika
- Spanish: Jambu
- Swedish: Tandvärksplanta
- Tamil: Vana- Mugali
- Thai: ผักคราดหัวแหวน
- Vietnamese: Cúc áo
Used to treat toothache, throat and gum infections, immune booster, dysentery, rheumatism, malaria (prevention and treatment) [Handbook of African Medicinal Plants, Second Edition]
Leaf: Eaten as a salad to induce salivation. [Medicinal Plants of the Guianas (Guyana, Surinam, French Guiana) ]
50 Published articles of Acmella oleracea
1. Marchesini, P., et al., Activity of the extract of Acmella oleracea on immature stages of Amblyomma sculptum (Acari: Ixodidae). Veterinary Parasitology, 2018. 254: p. 147-150.
2. de Freitas-Blanco, V.S., et al., Spilanthol, the Principal Alkylamide from Acmella oleracea, Attenuates 5-Fluorouracil-Induced Intestinal Mucositis in Mice. Planta medica, 2018.
3. de Araujo, I.F., et al., Larvicidal effect of hydroethanolic extract from the leaves of Acmella oleracea L. R. K. Jansen in Aedes aegypti and Culex quinquefasciatus. South African Journal of Botany, 2018. 117: p. 134-140.
4. da Rocha, C.F., et al., Action of the hydroethanolic extract of the flowers of Acmella oleracea (L.) RK Jansen on the reproductive performance of Wistar females rats: A popular female aphrodisiac from the Amazon. Journal of Ethnopharmacology, 2018. 214: p. 301-308.
5. Benelli, G., et al., Insecticidal efficacy of the essential oil of jambu (Acmella oleracea (L.) R.K. Jansen) cultivated in central Italy against filariasis mosquito vectors, houseflies and moth pests. Journal of ethnopharmacology, 2018.
6. Barbosa, A.F., et al., Spilanthol Content in the Extract Obtained by Supercritical CO2 at Different Storage Times of Acmella Oleracea L. Journal of Food Process Engineering, 2017. 40(3).
7. Anholeto, L.A., et al., Toxic action of Acmella oleracea extract on the male reproductive system of Amblyomma cajennense ticks. Veterinary Parasitology, 2017. 244: p. 164-171.
8. Anholeto, L.A., et al., Potential action of extract of Acmella oleracea (L.) RK Jansen to control Amblyomma cajennense (Fabricius, 1787) (Acari: Ixodidae) ticks. Ticks and Tick-Borne Diseases, 2017. 8(1): p. 65-72.
9. Yamane, L.T., et al., Acmella oleracea and Achyrocline satureioides as Sources of Natural Products in Topical Wound Care. Evidence-Based Complementary and Alternative Medicine, 2016.
10. Yamane, L.T., et al., Acmella oleracea and Achyrocline satureioides as Sources of Natural Products in Topical Wound Care. Evidence-based complementary and alternative medicine : eCAM, 2016. 2016: p. 3606820-3606820.
11. Gerbino, A., et al., Spilanthol from Acmella oleracea lowers Na+-K+-2Cl(-)-cotransporter activity and water channel aquaporin 2 membrane expression in mouse renal cells. Faseb Journal, 2016. 30.
12. Gerbino, A., et al., Spilanthol from Acmella Oleracea Lowers the Intracellular Levels of cAMP Impairing NKCC2 Phosphorylation and Water Channel AQP2 Membrane Expression in Mouse Kidney. Plos One, 2016. 11(5).
13. Franca, J.V., et al., Distinct growth and extractive methods of Acmellaoleracea (L.) RK Jansen rising different concentrations of spilanthol: An important bioactive compound in human dietary. Food Research International, 2016. 89: p. 781-789.
14. De Freitas-Blanco, V.S., et al., Development and Evaluation of a Novel Mucoadhesive Film Containing Acmella oleracea Extract for Oral Mucosa Topical Anesthesia. Figshare, 2016.
15. de Freitas-Blanco, V.S., et al., Development and Evaluation of a Novel Mucoadhesive Film Containing Acmella oleracea Extract for Oral Mucosa Topical Anesthesia. Plos One, 2016. 11(9).
16. Cruz, P.B., et al., Acaricidal activity of methanol extract of Acmella oleracea L. (Asteraceae) and spilanthol on Rhipicephalus microplus (Acari: Ixodidae) and Dermacentor nitens (Acari: Ixodidae). Veterinary Parasitology, 2016. 228: p. 137-143.
17. Borges, L.d.S., et al., Antioxidant compounds of organically and conventionally fertilized jambu (Acmella oleracea). Biological Agriculture & Horticulture, 2016. 32(3): p. 149-158.
18. Bonner, P., et al., Topical compositions comprising Acmella oleracea extracts and uses thereof. 2016, Johnson and Johnson Consumer Inc.
19. Barbosa, A.F., et al., Effects of Acmella oleracea methanolic extract and fractions on the tyrosinase enzyme. Revista Brasileira De Farmacognosia-Brazilian Journal of Pharmacognosy, 2016. 26(3): p. 321-325.
20. Barbosa, A.F., et al., Microbiological and sensory evaluation of Jambu (Acmella oleracea L.) dried by cold air circulation. Food Science and Technology, 2016. 36(1): p. 24-29.
21. Cheng, Y.-B., et al., Alkylamides of Acmella oleracea. Molecules, 2015. 20(4): p. 6970-6977.
22. Rodrigues, D.S., et al., Influência da adubação com nitrogênio e fósforo na produção de Jambu, Acmella oleracea (L) R.K. Jansen. Revista Brasileira de Plantas Medicinais, 2014. 16(1): p. 71-76.
23. Maria-Ferreira, D., et al., Rhamnogalacturonan from Acmella oleracea (L.) RK Jansen: Gastroprotective and Ulcer Healing Properties in Rats. Plos One, 2014. 9(1).
24. Castro, K.N.C., et al., Acaricide activity in vitro of Acmella oleracea against Rhipicephalus microplus. Parasitology Research, 2014. 113(10): p. 3697-3701.
25. Simas, N.K., et al., Acetylenic 2-phenylethylamides and new isobutylamides from Acmella oleracea (L.) R. K. Jansen, a Brazilian spice with larvicidal activity on Aedes aegypti. Phytochemistry Letters, 2013. 6(1): p. 67-72.
26. Ogata Nomura, E.C., et al., Antinociceptive effects of ethanolic extract from the flowers of Acmella oleracea (L.) RK Jansen in mice. Journal of Ethnopharmacology, 2013. 150(2): p. 583-589.
27. Nascimento, A.M., et al., Gastroprotective effect and structure of a rhamnogalacturonan from Acmella oleracea. Phytochemistry, 2013. 85: p. 137-142.
28. Moreno, S.C., et al., Bioactivity of compounds from Acmella oleracea against Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) and selectivity to two non-target species. Pest Management Science, 2012. 68(3): p. 386-393.
29. Demarne, F. and G. Passaro, Use of an Acmella oleracea extract for the botulinum toxin-like effect thereof in an anti-wrinkle cosmetic composition. 2009, Gattefosse SAS.
30. Malosso, M.G., E.P. Barbosa, and E.O. Nagao, Micropropagation of "jambu" Acmella oleracea (L.) RK Jansen. Revista Brasileira de Plantas Medicinais, 2008. 10(3): p. 91-95.
31. Hind, N. and N. Biggs, Acmella oleracea. Curtis's Botanical Magazine, 2003. 20(1): p. 31-39.
32. Singh, Y.P., et al., Spilanthes acmella and Spilanthes oleracea: new hosts of root-knot nematode. Annals of Forestry, 2000. 8(2): p. 282-284.
33. Nakatani, N. and M. Nagashima, PUNGENT ALKAMIDES FROM SPILANTHES-ACMELLA L VAR OLERACEA CLARKE. Bioscience Biotechnology and Biochemistry, 1992. 56(5): p. 759-762.
34. Moreira, V., et al., CHARACTERIZATION OF CONVULSIONS INDUCED BY A HEXANIC EXTRACT OF SPILANTHES-ACMELLA VAR OLERACEA IN RATS. Brazilian Journal of Medical and Biological Research, 1989. 22(1): p. 65-67.
35. Wang, X., Acmella oleracea milk flavor soup material useful for e.g. removing stasis and swelling, contains Acmella oleracea, cattail pollen, wampee, Chimonanthus, radix tinosporae, Sagina, sheep milk powder, cassava starch and flavoring powder. Harbin Shengyi Biological Technology Dev.
36. Unannounced, I., Mask used for e.g. preventing aging, comprises mask substrate and mask essence comprising water-soluble thickening agent, humectant including polyol, antioxidant composition containing Acmella oleracea extract, and aqueous carrier. Foshan Wensente Intellectual Property.
37. Sun, B., Medicinal preparation used for treating viral myocarditis, contains Bergenia, Dendrobium nobile, Acmella oleracea, Pteris semipinnata, peach kernel, common Andrographis herb, root of common peony, honeysuckle, and Chinese Pulsatilla. Quanjiao Xianqi Medical Technology Co.
38. Shukla, U., Herbal formulation used to treat metabolic disorders comprising high blood glucose, high blood cholesterol and high triglyceride levels, comprises herb including e.g. Acmella oleracea, Carum carvi and Terminalia bellerica, and carrier. Shukla U.
39. Reinhart, G.M. and M.D. Helman, Pigmented color cosmetic composition useful in foundation makeups, blushes, eyeshadows or mascaras comprises an extract of Acmella Oleracea in carrier. Reinhart G M; Helman M D.
40. Li, Y., Healthcare product used for preventing and treating liver injury, comprises herba Cistanche, Kadsura longipedunculata, Acmella oleracea, radix arnebiae seu lithospermi, Luisia teretifolia and robust Leontice rhizome and root. Nanjing Duobao Biological Technology Co.
41. Li, Y., Selenium-enriched healthcare product useful for replenishing qi and enriching blood comprises sodium selenite, Acmella oleracea, yellowhairy Oreocharis, Perilla stem and Thesium. Nanjing Duobao Biological Technology Co.
42. Jae, S.K., Producing Schisandra chinensis beverage, comprises producing Schisandra chinensis blue, and mixing carbonated water and Acmella oleracea leaf extract into the Schisandra chinensis blue. Agric Corp Mungyeongmall Corp.
43. Heinen, S., et al., Cosmetic composition used in cosmetic skin care method as gel or serum, contains extract of Acmella oleracea, extract of Quassia amara, hydrolyzed protein, and purine derivative. Henkel & Co Ag Kgaa.
44. Fu, M., et al., Traditional Chinese medicinal extract useful for e.g. treating cold and asthma, relieving fatigue and body pain, and eliminating phlegm, comprises Asprella, Acmella oleracea, rose apple, Clerodendrum extract, and Atropa belladonna. Zhejiang Pangu Medicinal Herbs Resource.
45. Demarne, F., G. Passaro, and F.L. Demarne, Use of spilanthol, e.g. in the form of an Acmella oleracea extract, to make a cosmetic antiwrinkle composition. Gattefosse Sa; Gattefosse Sas.
46. Dan, X., Traditional Chinese medicinal composition useful for treating ureteral stones, contains Spilanthes callimorpha, Acmella oleracea, Huperzia serrata, Selaginella tamariscina, Lanceolaria grayana and Peperomia dindygulensis. Dan X.
47. Bonner, P., et al., Topical analgesic composition used e.g. for relieving or reducing edema of skin and/or muscles, comprises Acmella oleracea extract, terpene-containing extract comprising Cistus ladanifer oil and/or Cupressus sempervirens oil, and carrier. Bonner P; Dinapoli M a; Kaminski C; Reynertson K a; Johnson & Johnson Consumer Co Inc; Johnson & Johnson Consumer Inc; Johnson & Johnson Consumer Prod.
48. Belfer, W.A., Composition useful for preventing and healing wrinkles in sun-damaged/aging skin caused by facial expression comprises extract of Acmella oleracea; dermal stimulating peptide; additional skin care active e.g. vitamin and inert cosmetic base. Belfer W A.
49. Bio-botox product useful as cosmetic product, comprises e.g. hyaluronic acid, alcohol, Acmella oleracea extract, argireline powder, glycerol, Heliantus annus seed extract, decyl glucoside, hydrolyzed silk, potassium sorbate, benzyl alcohol. Calvo D.
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