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Friday, April 4, 2014

Tinospora crispa, イボツヅラフジ., Liane-quinine

Tinospora crispa (L.) Hook. f. & Thomson
Family: Menispermaceae
Synonyms: Menispermum crispum L., Tinospora gibbericaulis Hand.-Mazz., Tinospora mastersii Diels, Tinospora rumphii, Tinospora thorelii Gagnep.

Chinese: 发冷藤, 波叶青牛胆
French: Liane-quinine.
Japanese:  イボツヅラフジ.
Thai:  บอระเพ็ด   Bora phet,  Chung ching, Kuakhohoo (Don Daeng).

Description: Tinospora crispa (L.) Diels is a woody climber with numerous protrusions on the stem. Leaves are oblong-ovate, cordate, 8-9 cm by 7-8 cm and tapering to a pointed end. Flowers are small, with 6 petals, 2 mm in length and 8-27 cm racemes. Male flowers have yellow sepals whereas female flowers have green sepals. Drupelets are red, juicy and 7-8 mm long.[A Guide to Medicinal Plants - An Illustrated, Scientific and
Medicinal Approach]

Action: Antipyretic, Appetizer, Bitter Tonic, Lymphatic, Pectoral, Stomachic
Part Used: Stem
Internal Application: Boraphet (pronounced “bora-pet”) is used to treat any disease in which fever is the initial symptom. It also stimulates the appetite and is considered to be a bitter tonic especially beneficial for the lungs, bile, and lymphatic system. The Wat Po texts mention boraphet as a cure for intestinal parasites, stomach problems in babies, malaria, eye and ear disease, and for mucous congestion. Preparation: A foot-long segment of stem (about 30–40 grams) is pounded with a mortar and pestle. Mashed stalks are soaked in water, and strained. Decoction is drunk twice daily until fever is gone. Or one inch of fresh stem is chewed with lots of water 2–3 times daily. [A COMPENDIUM OF TRADITIONAL THAI HERBAL MEDICINE]

Action: Plant—diuretic, as powerful a febrifuge as cinchona. The plant contains a bitter principle picrotein and furanoditerpene glycoside, tinocrisposide. Stem, roots and tubers contain a diterpenoid— tinosporan, which appears to be closely related to columbin. [Indian Medicinal Plants An Illustrated Dictionary]

Stem: Macerated in rum, cognac or absinthe and mixed with bark of Quassia amara into a bitter beverage to control diabetes and albuminuria; macerated in rum or white wine for a malaria remedy; macerated in white wine for a vermifuge and an appetite stimulant for infants. CHEM: Contains the antidiabetic alkaloid palmatine. [Medicinal Plants of the Guianas (Guyana, Surinam, French Guiana)]

73 Published articles of Tinospora crispa
1.    Anticholinesterase inhibitory activity of quaternary alkaloids from Tinospora crispa.
Yusoff, Mashitah; Hamid, Hazrulrizawati; Houghton, Peter
Molecules (Basel, Switzerland)  Volume: 19   Issue: 1   Pages: 1201-11   Published: 2014 Jan 20
2.    Anticholinesterase inhibitory activity of quaternary alkaloids from Tinospora crispa.
Mashitah Yusoff; Hazrulrizawati Hamid; Houghton, P.
Molecules  Volume: 19   Issue: 1   Pages: 1201-1211   Published: 2014
3.    Anti-diabetic effect of oral borapetol B, isolated from the plant tinospora crispa, by stimulating insulin release in type 2 diabetic Goto-Kakizaki rats
Lokman, E. F.; Gu, H. F.; Mohamood, W. Wan; et al.
Conference: 49th Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD) Location: Barcelona, SPAIN Date: SEP 23-27, 2013
Sponsor(s): European Assoc Study Diabet
DIABETOLOGIA  Volume: 56   Supplement: 1   Pages: S200-S201   Meeting Abstract: 482   Published: SEP 2013
4.    Crude extract and purified components isolated from the stems of Tinospora crispa exhibit positive inotropic effects on the isolated left atrium of rats
Praman, Siwaporn; Mulvany, Michael J.; Williams, David E.; et al.
JOURNAL OF ETHNOPHARMACOLOGY  Volume: 149   Issue: 1   Pages: 123-132   Published: AUG 26 2013
5.    A Review of the Secondary Metabolites and Biological Activities of Tinospora crispa (Menispermaceae)
Koay, Yen Chin; Amir, Faheem
TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH  Volume: 12   Issue: 4   Pages: 641-649   Published: AUG 2013
6.    Hypoglycemic action of borapetoside A from the plant Tinospora crispa in mice.
Ruan, Chi-Tun; Lam, Sio-Hong; Lee, Shoei-Sheng; et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology  Volume: 20   Issue: 8-9   Pages: 667-75   Published: 2013-Jun-15 (Epub 2013 Mar 20)
7.    Antioxidant Activity of Methanol Extract of Tinospora crispa and Tabernaemontana corymbosa
Zulkefli, Heida Nadia; Mohamad, Jamaludin; Abidin, Nurhayati Zainal
SAINS MALAYSIANA  Volume: 42   Issue: 6   Pages: 697-706   Published: JUN 2013
8.    Acute hepatitis and jaundice due to Tinospora sinensis or Tinospora crispa
Wu, Ming-Ling; Deng, Jou-Fang; Yang, Chen-Yang
CLINICAL TOXICOLOGY  Volume: 51   Issue: 4   Pages: 268-269   Meeting Abstract: 31   Published: MAY 2013
9.    Antidiabetic Effect of Oral Borapetol B Compound, Isolated from the Plant Tinospora crispa, by Stimulating Insulin Release.
Lokman, Faradianna E; Gu, Harvest F; Wan Mohamud, Wan Nazaimoon; et al.
Evidence-based complementary and alternative medicine : eCAM  Volume: 2013   Pages: 727602   Published: 2013 (Epub 2013 Nov 10)
10.    Antidiabetic effect of oral borapetol B compound, isolated from the plant Tinospora crispa, by stimulating insulin release.
Lokman, F. E.; Gu, H. F.; Wan Nazaimoon, W. M.; et al.
Evidence-based Complementary and Alternative Medicine  Volume: 2013   Pages: Article ID 727602   Published: 2013
11.    Antidiabetic Effect of Oral Borapetol B Compound, Isolated from the Plant Tinospora crispa, by Stimulating Insulin Release
Lokman, Faradianna E.; Gu, Harvest F.; Mohamud, Wan Nazaimoon Wan; et al.
EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE    Article Number: 727602   Published: 2013
12.    Antioxidant activity of methanol extract of Tinospora crispa and Tabernaemontana corymbosa.
Heida Nadia Zulkefli; Jamaludin Mohamad; Nurhayati Zainal Abidin
Sains Malaysiana  Volume: 42   Issue: 6   Pages: 697-706   Published: 2013
13.    Anti-hiperglikemia herbal remedy composition used for treating diabetes, comprises Tinospora crispa, Guazuma ulmifolia, and Taraxacum officinale
Patent Number: ID201202991-A
Patent Assignee: DARWIN K
Inventor(s): DARWIN K.
14.    Evaluation of thrombolytic activity and brine shrimp lethality bioassay of methanol extract of stems of Tinospora crispa.
Islam, M. A.; Mahmud, Z. A.; Rahman, S. M. A.; et al.
International Journal of Pharmaceutical Sciences and Research (IJPSR)  Volume: 4   Issue: 3   Pages: 1148-1153   Published: 2013
15.    Borapetoside C from Tinospora crispa improves insulin sensitivity in diabetic mice
Ruan, Chi-Tun; Lam, Sio-Hong; Chi, Tzong-Cherng; et al.
PHYTOMEDICINE  Volume: 19   Issue: 8-9   Pages: 719-724   Published: JUN 15 2012
16.    Hypotensive and cardio-chronotropic constituents of Tinospora crispa and mechanisms of action on the cardiovascular system in anesthetized rats
Praman, Siwaporn; Mulvany, Michael J.; Williams, David E.; et al.
JOURNAL OF ETHNOPHARMACOLOGY  Volume: 140   Issue: 1   Pages: 166-178   Published: MAR 6 2012
17.    Hypoglycemic Diterpenoids from Tinospora crispa
Lam, Sio-Hong; Ruan, Chi-Tun; Hsieh, Po-Hung; et al.
JOURNAL OF NATURAL PRODUCTS  Volume: 75   Issue: 2   Pages: 153-159   Published: FEB 2012
18.    Alkaloids content, cytotoxicity and anti-Toxoplasma gondii activity of Psidium guajava L. and Tinospora crispa
Lee, Wei Cai; Mahmud, Roziahanim; Noordin, Rahmah; et al.
BANGLADESH JOURNAL OF PHARMACOLOGY  Volume: 7   Issue: 4   Pages: 272-276   Published: 2012
19.    Antimicrobial activity of Tinospora crispa root extracts.
Mohammed, A. I. C.; Gunjan Manish; Dinesh, C. K.
International Journal of Research in Ayurveda and Pharmacy (IJRAP)  Volume: 3   Issue: 3   Pages: 417-419   Published: 2012
20.    Inhibitory properties of Tinospora crispa extracts on TNF-alpha induced inflammation on Human Umbilical Vein Endothelial Cells (HUVECS).
Ihsan Safwan Kamarazaman; Amom, Z. H.; Rasadah Mat Ali; et al.
International Journal of Tropical Medicine  Volume: 7   Issue: 1   Pages: 24-29   Published: 2012
21.    Protective effects of Tinospora crispa extracts on H 2O 2-induced oxidative stress and TNF-alpha-induced inflammation on human umbilical vein endothelial cells (HUVECs).
Ihsan Safwan Kamarazaman; Zulkhairi Hj. Amom; Rasadah Mat Ali; et al.
Journal of Medicinal Plants Research  Volume: 6   Issue: 15   Pages: 3013-3021   Published: 2012
22.    The Effect of Tinospora crispa on Serum Glucose and Insulin Levels in Patients with Type 2 Diabetes Mellitus
Klangjareonchai, Theerawut; Roongpisuthipong, Chulaporn
JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY    Article Number: 808762   Published: 2012
23.    The effect of Tinospora crispa on serum glucose and insulin levels in patients with type 2 diabetes mellitus.
Klangjareonchai, Theerawut; Roongpisuthipong, Chulaporn
Journal of biomedicine & biotechnology  Volume: 2012   Pages: 808762   Published: 2012 (Epub 2011 Nov 02)
24.    AN AQUEOUS EXTRACT OF TINOSPORA CRISPA POSSESSES ANTIOXIDATIVE PROPERTIES AND REDUCES ATHEROSCLEROSIS IN HYPERCHOLESTEROLEMIC-INDUCED RABBITS
Amom, Zulkhairi; Azman, Khairunnuur Fairuz; Ismail, Nor Amalina; et al.
JOURNAL OF FOOD BIOCHEMISTRY  Volume: 35   Issue: 4   Pages: 1083-1098   Published: AUG 2011
25.    Effect of Tinospora crispa on glucose uptake in skeletal muscle: role of glucose transporter 1 expression and extracellular signal-regulated kinase1/2 activation
Noipha, Kusumarn; Ratanachaiyavong, Suvina; Purintrapiban, Juntipa; et al.
ASIAN BIOMEDICINE  Volume: 5   Issue: 3   Pages: 361-369   Published: JUN 2011
26.    Effect of Tinospora crispa on thioacetamide-induced liver cirrhosis in rats
Kadir, Farkaad A.; Othman, Faizah; Abdulla, Mahmood Ameen; et al.
INDIAN JOURNAL OF PHARMACOLOGY  Volume: 43   Issue: 1   Pages: 64-68   Published: JAN-FEB 2011
27.    Effects of an n-butanol extract from the stem of Tinospora crispa on blood pressure and heart rate in anesthetized rats
Praman, Siwaporn; Mulvany, Michael J.; Allenbach, Yves; et al.
JOURNAL OF ETHNOPHARMACOLOGY  Volume: 133   Issue: 2   Pages: 675-686   Published: JAN 27 2011
28.    Anti-proliperative and antioxidant effects of Tinospora crispa (Batawali)
Ibahim, M. J.; I'zzah, Wan-Nor W. M. Z.; Narimah, A. H. H.; et al.
BIOMEDICAL RESEARCH-INDIA  Volume: 22   Issue: 1   Pages: 57-62   Published: JAN-MAR 2011
29.    An aqueous extract of Tinospora crispa possesses antioxidative properties and reduces atherosclerosis in hypercholesterolemic-induced rabbits.
Zulkhairi Amom; Khairunnuur Fairuz Azman; Nor Amalina Ismail; et al.
Journal of Food Biochemistry  Volume: 35   Issue: 4   Pages: 1083-1098   Published: 2011
30.    Insecticidal efficacy of Tinospora crispa Miers. extracts by different solvents on diamondback moth larvae.
Ruenrom, K.; Tantakom, S.; Thongket, T.
Conference: Proceedings of the Kasetsart University Annual Conference, Volume 1: Plants, Kasetsart, Thailand, 1-4 February, 2011.
Proceedings of the 49th Kasetsart University Annual Conference, Kasetsart University, Thailand, 1-4 February, 2011. Volume 1. Subject: Plants  Pages: 93-98   Published: 2011
31.    Antioxidant properties of aqueous and methanol extract from Tinospora crispa and its ability to attenuate hydrogen peroxide-induced stress injury in human umbilical vein endothelial cells.
Ihsan, S. K.; Zulkhairi, H. A.; Abdah, M. A.; et al.
Research Journal of Biological Sciences  Volume: 6   Issue: 5   Pages: 230-236   Published: 2011
32.    In vitro interaction of combined plants: Tinospora crispa and Swietenia mahagoni against Methicillin-resistant Staphylococcus aureus (MRSA)
Al-alusi, N. T.; Kadir, F. A.; Ismail, S.; et al.
AFRICAN JOURNAL OF MICROBIOLOGY RESEARCH  Volume: 4   Issue: 21   Pages: 2309-2312   Published: NOV 4 2010
33.    Alkaloidal Constituents of Tinospora crispa
Choudhary, M. Iqbal; Ismail, Muhammad; Ali, Zulfiqar; et al.
NATURAL PRODUCT COMMUNICATIONS  Volume: 5   Issue: 11   Pages: 1747-1750   Published: NOV 2010
34.    Anti-Cancer Compound Screening and Isolation: Coscinium fenestratum, Tinospora crispa and Tinospora cordifolia
Tungpradit, Rudeewan; Sinchaikul, Supachok; Phutrakul, Suree; et al.
CHIANG MAI JOURNAL OF SCIENCE  Volume: 37   Issue: 3   Pages: 476-488   Published: SEP 2010
35.    cis-Clerodane-Type Furanoditerpenoids from Tinospora crispa
Choudhary, M. Iqbal; Ismail, Muhammad; Shaari, Khozirah; et al.
JOURNAL OF NATURAL PRODUCTS  Volume: 73   Issue: 4   Pages: 541-547   Published: APR 2010
36.    Medicine, useful for curing rheumatism comprises stem of manyflower Fissistigma, Cassia twig, Uncaria, Sappan wood, Lycopodium clavatum, Tinospora crispa(L.)Hook.F.etThoms and Mappianthus iodoies
Patent Number: CN101810709-A
Patent Assignee: XISHUANGBANNA DAI AUTONOMOUS PREFECTURE MINORITY MEDICINE IN
Inventor(s): LIU Z; TAN Z; DENG Q; et al.
37.    Cosmetic or dermatological topical composition, useful e.g. for the indication of intrinsic and extrinsic skin aging, comprises antioxidant e.g. Tinospora crispa stem extract, and active substance e.g. 7-methoxy-2,2-dimethyl-chroman-6-ol
Patent Number: DE102009037537-A1
Patent Assignee: HENKEL & CO AG KGAA
Inventor(s): DICKHOF S; EMOND E; JANSSEN F; et al.
38.    IN VIVO ANTIPARASITIC ACTIVITY OF THE THAI TRADITIONAL MEDICINE PLANT-TINOSPORA CRISPA-AGAINST PLASMODIUM YOELII
Rungruang, Thanaporn; Boonmars, Thidarut
SOUTHEAST ASIAN JOURNAL OF TROPICAL MEDICINE AND PUBLIC HEALTH  Volume: 40   Issue: 5   Pages: 898-900   Published: SEP 2009
39.    Process for isolation of bergenin from Tinospora crispa with antioxidant and free radical scavenging activity
Patent Number: IN193547-B
Patent Assignee: COUNCIL SCI&IND RES INDIA
Inventor(s): GHULAM N Q; KHAJURIA A; MANHAS L R; et al.
40.    THAI TRADITIONAL MEDICINE PLANT, TINOSPORA CRISPA, AFFECTS THE PLASMODIUM INFECTIVITY IN VIVO
Rungruang, Thanaporn; Boonmars, Thidarut
Conference: 57th Annual Meeting of the American-Society-of-Tropical-Medicine-and-Hygiene Location: New Orleans, LA Date: DEC 07-11, 2008
Sponsor(s): Amer Soc Trop Med & Hyg
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE  Volume: 79   Issue: 6   Pages: 54-54   Meeting Abstract: 181   Published: DEC 2008
41.    In vitro glucose uptake activity of Tinospora crispa in skeletal muscle cells. (vol 2, pg 415, 2008)
Noipha, Kusumarn; Purintrapiban, Juntipa; Herunsalee, Angkana; et al.
ASIAN BIOMEDICINE  Volume: 2   Issue: 6   Pages: 515-515   Published: DEC 2008
42.    In vitro glucose uptake activity of Tinospora crispa in skeletal muscle cells
Noipha, Kusumam; Purintrapiban, Juntipa; Herunsalee, Angkana; et al.
ASIAN BIOMEDICINE  Volume: 2   Issue: 5   Pages: 415-420   Published: OCT 2008
43.    Biological Properties of Tinospora crispa (Akar Patawali) and Its Antiproliferative Activities on Selected Human Cancer Cell Lines.
Zulkhairi, A Jr; Abdah, M A; M Kamal, N H; et al.
Malaysian journal of nutrition  Volume: 14   Issue: 2   Pages: 173-87   Published: 2008-Sep (Epub 2008 Sep 15)
44.    Effects of an n-butanol extract from stems of Tinospora crispa on blood pressure and heart rate in anesthetized rats
Jansakul, C.; Praman, S.
FUNDAMENTAL & CLINICAL PHARMACOLOGY  Volume: 22   Supplement: 2   Pages: 69-69   Published: AUG 2008
45.    Effects of an n-butanol extract from stems of Tinospora crispa on rat atria and thoracic aorta and on a guinea pig trachea in vitro
Praman, S.; Jansakul, C.
FUNDAMENTAL & CLINICAL PHARMACOLOGY  Volume: 22   Supplement: 2   Pages: 69-69   Published: AUG 2008
46.    Antinociceptive and anti-inflammatory activities of Tinospora crispa in various animal models.
Sulaiman, M. R.; Zakaria, Z. A.; Lihan, R.
International Journal of Tropical Medicine  Volume: 3   Issue: 3   Pages: 66-69   Published: 2008
47.    Malarial prophylaxis with medicinal plants: Toxic hepatitis due to Tinospora crispa
Denis, Guillaume; Gerard, Yann; Sahpaz, Sevser; et al.
THERAPIE  Volume: 62   Issue: 3   Pages: 271-272   Published: MAY-JUN 2007
48.    Bergenin as antioxidant free radical scavenging activity from Tinospora crispa
Patent Number: IN200101109-I1; IN217147-B
Patent Assignee: COUNCIL SCI&IND RES INDIA
Inventor(s): MAURYA R; MANAHAS L R; SINGH S; et al.
49.    Raising systems and supplementation of Tinospora crispa on production performance of indigenous pigs
Buakeeree, Kruan; Thepparat, Mongkol
Book Group Author(s): Kasetsart Univ
Conference: 44th Kasetsart-University Annual Conference Location: Bangkok, THAILAND Date: JAN 30-FEB 02, 2006
Sponsor(s): Kasetsart Univ; Commiss Higher Educ; Minist Educ; Minist Agr & Cooperat; Minist Sci & Technol; Minist Nat Resources & Environm; Minist Informat & Commun Technol; Natl Res Council Thailand; Thailand Res Fund
Proceedings of the 44th Kasetsart University Annual Conference: ANIMALS; VETERINARY MEDICINE  Pages: 382-390   Published: 2006
50.    The effects of extracts from Curcuma longa, Paederia tomentosa and Tinospora crispa on stress and immunity of broiler chickens.
Jindamongkon, K.; Isariyodom, S.; Tirawattanawanich, C.; et al.
Conference: Proceedings of 43rd Kasetsart University Annual Conference, Thailand, 1-4 February, 2005. Subject: Animals.
Proceedings of 43rd Kasetsart University Annual Conference, Thailand, 1-4 February, 2005. Subject: Animals  Pages: 202-210   Published: 2005
51.    Randomized controlled trial of Tinospora crispa for additional therapy in patients with type 2 diabetes mellitus
Sangsuwan, Chawanya; Udompanthurak, Suthipol; Vannasaeng, Sathit; et al.
Journal of the Medical Association of Thailand  Volume: 87   Issue: 5   Pages: 543-546   Published: May 2004
52.    Extraction evaluation of hypoglycaemic property and acute toxicity testing of extracts from Tinospora crispa stems (in Thai)
Kongkathip, N; Jnakana, S; Kongkathip, B; et al.
Book Group Author(s): Kasetsart Univ
Conference: 42nd Kasetsart-University Annual Conference Location: THAILAND Date: FEB 03-06, 2004
Sponsor(s): Kasetsart Univ; Commiss Higher Educ; Minist Educ; Minist Agr & Cooperat; Minist Sci & Technol; Minist Nat Resources & Envirnom; Minist Informat Commun Technol; Natl Res Council Thailand; Thailand Res Fund
PROCEEDINGS OF 42ND KASETSART UNIVERSITY ANNUAL CONFERENCE  Pages: 279-288   Published: 2004
53.    Study on cardiac contractility of cycloeucalenol and cycloeucalenone isolated from Tinospora crispa
Kongkathip, N; Dhumma-upakorn, P; Kongkathip, B; et al.
JOURNAL OF ETHNOPHARMACOLOGY  Volume: 83   Issue: 1-2   Pages: 95-99   Article Number: PII S0378-8741(02)00210-6   Published: NOV 2002
54.    Purification and characterization of a trypsin inhibitor from Tinospora crispa
Zeng Ying; Sang Yu-Ying; Hu Jin-Yong; et al.
Acta Botanica Yunnanica  Volume: 24   Issue: 1   Pages: 103-108   Published: Feb., 2002
55.    Callus induction from Andrographis paniculata and Tinospora crispa.
Nor Hasnida Hassan; Salbiah Man; Aziah Mohd Yusoff
Edited Chang YuShyun; Mohtar, M.; Subramaniam, V.; et al.
Conference: Towards modernisation of research and technology in herbal industries. Proceedings of the Seminar on Medicinal and Aromatic Plants, 24-25 July 2001.
Towards modernisation of research and technology in herbal industries. Proceedings of the Seminar on Medicinal and Aromatic Plants, 24-25 July 2001  Pages: 254-260   Published: 2002
56.    Pharmacological characterisation of the antihyperglycaemic properties of Tinospora crispa extract
Noor, H; Ashcroft, SJH
JOURNAL OF ETHNOPHARMACOLOGY  Volume: 62   Issue: 1   Pages: 7-13   Published: AUG 1998
57.    Antioxidant and lipophilic constituents of Tinospora crispa
Cavin, A; Hostettmann, K; Dyatmyko, W; et al.
PLANTA MEDICA  Volume: 64   Issue: 5   Pages: 393-396   Published: JUN 1998
58.    Insulinotropic activity of Tinospora crispa extract: Effect on beta-cell Ca2+ handling
Noor, H; Ashcroft, SJH
PHYTOTHERAPY RESEARCH  Volume: 12   Issue: 2   Pages: 98-102   Published: MAR 1998
59.    Flavone O-glycosides from Tinospora crispa
Kalsom, Y. Umi; Noor, H.
Fitoterapia  Volume: 66   Issue: 3   Pages: 280   Published: 1995
60.    Flavone O-glycosides from Tinospora crispa.
Umi Kalsom, Y.; Noor, H.
Fitoterapia  Volume: 66   Issue: 3   Pages: 280   Published: 1995
61.    Inhibitory effects of Siamese Tinospora crispa extracts on carrageenin induced foot pad edema in rats
Higashino, Hideaki; Suzuki, Aritomo
Conference: 66th Annual Meeting of the Japanese Pharmacological Society Location: Yokohama, Japan Date: March 24-27, 1993
Japanese Journal of Pharmacology  Volume: 61   Issue: SUPPL. 1   Pages: 162P   Published: 1993
62.    TINOCRISPOSIDE, A NEW BITTER FURANODITERPENE GLYCOSIDE FROM TINOSPORA-CRISPA MIERS
PACHALY, P; ADNAN, AZ
ARCHIV DER PHARMAZIE  Volume: 325   Issue: 11   Pages: 705-708   Published: NOV 1992
63.    INHIBITORY EFFECTS OF SIAMESE TINOSPORA-CRISPA EXTRACTS ON THE CARRAGEENAN-INDUCED FOOT PAD EDEMA IN RATS (THE 1ST REPORT)
HIGASHINO, H; SUZUKI, A; TANAKA, Y; et al.
FOLIA PHARMACOLOGICA JAPONICA  Volume: 100   Issue: 4   Pages: 339-344   Published: OCT 1992
64.    [Inhibitory effects of Siamese Tinospora crispa extracts on the carrageenin-induced foot pad edema in rats (the 1st report)].
Higashino, H; Suzuki, A; Tanaka, Y; et al.
Nihon yakurigaku zasshi. Folia pharmacologica Japonica  Volume: 100   Issue: 4   Pages: 339-44   Published: 1992-Oct
65.    NMR-ASSIGNMENTS OF N-ACYLAPORPHINE ALKALOIDS FROM TINOSPORA-CRISPA
PACHALY, P; ADNAN, AZ; WILL, G
PLANTA MEDICA  Volume: 58   Issue: 2   Pages: 184-187   Published: APR 1992
66.    ANTIDIABETIC EFFECTS OF TINOSPORA-CRISPA IN RATS
NOOR, H; ASHCROFT, SJH
JOURNAL OF ETHNOPHARMACOLOGY  Volume: 27   Issue: 1-2   Pages: 149-161   Published: NOV 1989
67.    THE HYPOGLYCEMIC AND INSULINOTROPIC ACTIVITY OF TINOSPORA-CRISPA - STUDIES WITH HUMAN AND RAT ISLETS AND HIT-T15 B-CELLS
NOOR, H; HAMMONDS, P; SUTTON, R; et al.
DIABETOLOGIA  Volume: 32   Issue: 6   Pages: 354-359   Published: JUN 1989
68.    N FORMYL AND N ACETYLAPORPHINE ALKALOIDS OF TINOSPORA-CRISPA
PACHALY P; ADNAN A Z; WILL G
Conference: 36TH ANNUAL CONGRESS OF THE SOCIETY FOR MEDICINAL PLANT RESEARCH, FREIBURG, WEST GERMANY, SEPTEMBER 1988. PLANTA MED.
Planta Medica  Volume: 55   Issue: 1   Pages: 115-116   Published: 1989
69.    THE STRUCTURE OF TINOCRISPOSIDE A BITTER FURANODITERPENE GLUCOSIDE FROM TINOSPORA-CRISPA
PACHALY P; ADNAN A Z
Conference: 37TH ANNUAL CONGRESS ON MEDICINAL PLANT RESEARCH, BRAUNSCHWEIG, WEST GERMANY, SEPTEMBER 5-9, 1989. PLANTA MED.
Planta Medica  Volume: 55   Issue: 7   Pages: 632   Published: 1989
70.    AN AQUEOUS EXTRACT FROM TINOSPORA CRISPA LOWERS BLOOD-GLUCOSE LEVELS IN ALLOXAN-DIABETIC RATS AND STIMULATES INSULIN RELEASE IN RAT ISLETS AND MAN
NOOR, H; HAMMONDS, P; ASHCROFT, SJH
DIABETOLOGIA  Volume: 31   Issue: 7   Pages: A526-A527   Published: JUL 1988
71.    PROTECTIVE EFFECT OF THE CRUDE EXTRACTS OF TINOSPORA-CRISPA AND OF VITEX-NEGUNDO IN LEUKOPENIC MICE WITH EXPERIMENTAL PSEUDOMONAS-AERUGINOSA URINARY TRACT INFECTION
SIA I C; NAKATA K; ARAKAWA S; et al.
ICMR (International Center for Medical Research) Annals  Pages: 89-100   Published: 1988
72.    PROTECTIVE EFFECT OF THE CRUDE EXTRACTS OF TINOSPORA-CRISPA AND OF VITEX-NEGUNDO IN LEUKOPENIC MICE WITH EXPERIMENTAL PSEUDOMONAS-AERUGINOSA URINARY TRACT INFECTION
SIA I C; NAKATA K; ARAKAWA S; et al.
ICMR (International Center for Medical Research) Annals  Pages: 89-100   Published: 1988

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