Family: Apocynaceae
Synonyms: Chonemorpha antidysenterica, Chonemorpha pubescens, Echites adglutinatus, Echites antidysentericus, Echites pubescens, Elytropus pubescens, Holarrhena antidysenterica, Holarrhena codaga, Holarrhena febrifuga, Holarrhena fischeri, Holarrhena glaberrima , Holarrhena glabra, Holarrhena macrocarpa, Holarrhena malaccensis, Holarrhena pierrei, Holarrhena tettensis, Holarrhena villosa, Nerium sinense, Physetobasis macrocarpa.
Assamese: dhulkari, dudkhuri
Bengali: kurchi, কুটজ kutaja
Chinese: Zhi xie mu
commonly known as: bitter oleander, cavessi bark, common holarrhena, coneru, conessi bark, dysentery rose bay, easter tree, ivory tree, kurchi bark, Tellicherry bark, white angel
Gujarati: drowda, kudakari
Hindi: कडवा इंद्रजव karva indrajau, kurchi, कुटज kutaja
Japanese: セイロンライティア
Kannada: koodsaloo, korchie
Konkani: कुडॉ kudo
Malayalam: കുടകപ്പാല kutakappaala
Marathi: इंद्रजव indrajav, kodaga, kodaga pala, कुटज kutaja, पांढरा कुडा paandhra kuda
Oriya: kherwa, korwa, kurwa, pitakorwa
Philippines: White Angel
Punjabi: keor, kewar
Sanskrit: इंद्रयव indrayava, कुटज kutaja, sakraparyaaya, sakraasana, vatsaka
Tamil: கிரிமல்லிகை kirimllikai, குடசப்பாலை kutaca-p-palai, மலைமல்லிகை mlaimllikai
Telugu: గిరిమల్లిక girimallika, కొడిసెపాల kodisepala, కోలముక్కు kolamukku, కొండమల్లె kondamalle, కుటజ kutaja, Kolamuki, Aakula paala
Thai: โมกหลวง Mok luang, โมกใหญ่ Mok yai
Ayurvedic uses: Carminative, expectorant, anthelmintic, Arsha, Atisara, Kushta, Pravahika, Trushna, Jvaratisara,
Root and bark—used in amoebic dysentery. Bark—astringent, anthelmintic, amoebicidal, diuretic. Used in colic, dyspepsia, piles, diseases of the skin and spleen. Seed—antibilious. Used for promoting conception, also for toning up vaginal tissues after delivery. Theplant possesses potentimmunostimulant property.
50 Published articles of Holarrhena pubescens / Holarrhena antidysenterica
1.
Antimicrobial activity of the methanolic bark
extract of Holarrhena pubescens
(Buch. Ham), its fractions and the pure compound conessine
Siddiqui Bina S.; Ali Syed Tahir; Rizwani Ghazala H.; et al.
- NATURAL PRODUCT RESEARCH Volume: 26 Issue: 11
Pages: 987-992 DOI: 10.1080/14786419.2010.537268
Published: 2012
2.
Triterpenoids and steroids from Holarrhena pubescens seeds
Bhattachartya Sanjib; Tarafdar Saswati; Saha Chandra Nath - PHARMACOGNOSY
MAGAZINE Volume: 5 Issue: 20 Supplement: S
Pages: 407-411 Published: DEC 2009
3.
Bioassay-directed isolation of hypotensive
alkaloid from Holarrhena pubescens
Aftab K.; Usmani S. B.; Begum S.; et al. - PLANTA
MEDICA Volume: 75 Issue: 9 Pages: 899-899
Published: JUL 2009
4.
Bioassay-directed isolation of hypotensive
alkaloid from Holarrhena pubescens
Aftab K.; Mazhar A.; Usmani S. B.; et al. - INDIAN JOURNAL
OF PHARMACOLOGY Volume: 40 Pages: 70-70
Meeting Abstract: 118 Published: OCT 2008
5.
Constituents of the leaves of Holarrhena
pubeseens
Tuntiwachwuttikul Pittaya; Pootaeng-on Yupa; Phansa
Potchana; et al. - FITOTERAPIA Volume: 78 Issue: 3
Pages: 271-273 DOI: 10.1016/j.fitote.2006.11.003
Published: APR 2007
6.
Two new constituents from the bark of Holarrhena pubescens
Siddiqui BS; Usmani SB; Ali ST; et al. - HETEROCYCLES Volume:
60 Issue: 4 Pages: 909-915 Published: APR 1
2003
7.
Further constituents from the bark of Holarrhena pubescens
Siddiqui BS; Usmani SB; Ali ST; et al. - PHYTOCHEMISTRY Volume:
58 Issue: 8 Pages: 1199-1204 DOI:
10.1016/S0031-9422(01)00330-2 Published: DEC 2001
8.
Antibacterial steroid alkaloids from the stem
bark of Holarrhena pubescens.
Chakraborty A; Brantner A H - Journal of
ethnopharmacology Volume: 68 Issue: 1-3
Pages: 339-44 DOI: 10.1016/S0378-8741(99)00119-1
Published: 1999-Dec-15
9.
HYPOTENSIVE CONSTITUENTS FROM THE BARK OF
HOLARRHENA-PUBESCENS (HOLARRHENA-ANTIDYSENTERICA)
SIDDIQUI BS; USMANI SB; BEGUM S; et al. - HETEROCYCLES Volume:
41 Issue: 2 Pages: 267-276 Published: FEB 1
1995
10.
ALKALOIDS FROM THE BARK OF HOLARRHENA-PUBESCENS
BEGUM S; USMANI SB; SIDDIQUI BS; et al. - PHYTOCHEMISTRY Volume:
36 Issue: 6 Pages: 1537-1541 DOI:
10.1016/S0031-9422(00)89757-5 Published: AUG 1994
11.
STEROIDAL CONSTITUENTS OF HOLARRHENA-PUBESCENS
SIDDIQUI BS; USMANI SB; BEGUM S; et al. - JOURNAL OF NATURAL
PRODUCTS Volume: 57 Issue: 1 Pages: 27-31
DOI: 10.1021/np50103a004 Published: JAN 1994
12.
Steroidal alkaloids from Holarrhena
antidysenterica as acetylcholinesterase inhibitors and the investigation for
structure-activity relationships
Yang Zhong-Duo; Duan Dong-Zhu; Xue Wei-Wei; et al. - LIFE
SCIENCES Volume: 90 Issue: 23-24 Pages:
929-933 DOI: http://dx.doi.org/10.1016/j. lfs.2012.04.017
Published: JUN 14 2012
13.
An in vivo study on the diuretic activity of
Holarrhena antidysenterica
Khan Aslam; Bashir Samra; Gilani Anwarul-Hassan - AFRICAN
JOURNAL OF PHARMACY AND PHARMACOLOGY Volume: 6 Issue: 7
Pages: 454-458 DOI: http://dx.doi.org/10.5897/ AJPP11.395
Published: FEB 2012
14.
Inhibitory effect of hydro-methanolic extract of
seed of Holarrhena antidysenterica on alpha-glucosidase activity and
postprandial blood glucose level in normoglycemic rat
Ali Kazi Monjur; Chatterjee Kausik; De Debasis; et al. - JOURNAL
OF ETHNOPHARMACOLOGY Volume: 135 Issue: 1
Pages: 194-196 DOI: http://dx.doi.org/10.1016/ jjep.2011.02.034
Published: APR 26 2011
15.
Anti-malarial activity of Holarrhena
antidysenterica and Viola canescens, plants traditionally used against malaria
in the Garhwal region of north-west Himalaya
Verma Gaurav; Dua Virendra K.; Agarwal Dau Dayal; et al. - MALARIA
JOURNAL Volume: 10 Article Number: 20
DOI: http://dx.doi.org/10.1186/ 1475-2875-10-20
Published: FEB 2 2011
16.
Herbal composition used for treating diarrhea
including painful flatulence or abdominal pain in humans, comprises blend of
extract of Aegle marmelos, Cyperus rotundus, Holarrhena antidysenterica,
Mangifera indica, and Zingiber officinale
Patent Number: WO2011083398-A2; IN201000022-I1;
WO2011083398-A3
Patent Assignee: HIMALAYA GLOBAL HOLDINGS LTD
17.
Monomer preparation of Holarrhena
antidysenterica total alkaloid extract to treat senile dementia, by extracting
Holarrhena antidysenterica by ethanol, extracting, and performing gel column
chromatography and thin-layer spectrum detection
Patent Number: CN102153614-A
Patent Assignee: UNIV LANZHOU TECHNOLOGY
18.
Pharmacological basis for the medicinal use of
Holarrhena antidysenterica in gut motility disorders
Gilani Anwarul Hassan; Khan Aslam; Khan Arif-ullah; et al. -
PHARMACEUTICAL BIOLOGY Volume: 48 Issue: 11
Pages: 1240-1246 DOI: http://dx.doi.org/10.3109/ 13880201003727960
Published: NOV 2010
19.
Effect of bitter tree (Holarrhena
antidysenterica) on the incidence of cashew stem and root borer (Plocaederus
ferrugineus)
Chakraborti S. - INDIAN JOURNAL OF AGRICULTURAL
SCIENCES Volume: 80 Issue: 7 Pages: 662-664 Published:
JUL 2010
20.
Rapid in vitro propagation of Holarrhena
antidysenterica using seedling cotyledonary nodes
Mallikarjuna K.; Rajendrudu G. - BIOLOGIA
PLANTARUM Volume: 53 Issue: 3 Pages: 569-572
DOI: http://dx.doi.org/10.1007/ s10535-009-0103-2 Published:
SEP 2009
21.
Inhibition of Enteropathogenic Escherichia coli
Adhesion on Host Epithelial Cells by Holarrhena antidysenterica (L.) WALL.
Kavitha D.; Niranjali S. - PHYTOTHERAPY
RESEARCH Volume: 23 Issue: 9 Pages:
1229-1236 DOI: http://dx.doi.org/10.1002/ptr. 2520
Published: SEP 2009
22.
The in vitro antidiarrhoeal activity of
Holarrhena antidysenterica (bark) wall extracts
Joshi P. V; Maheshwari V. L.; Surana S. J.; et al. - PLANTA
MEDICA Volume: 75 Issue: 9 Pages: 949-949
Published: JUL 2009
23.
In-vitro Multipication of Holarrhena
antidysenterica wall.-Medicinal Plant with Remedial Activity for Stomach
Ailments
Mahato Suchitra; Mehta Anita; Pandey R. K. - VEGETOS Volume:
22 Issue: 1 Pages: 17-22 Published: JUN
2009
24.
Pharmacological evaluation of holarrhena
antidysenterica (wall) for hypoglycemic activity in stz-induced diabetic rats
Srinivas V; Mana Supriya; Ansari M. D. Asif; et al. - INDIAN
JOURNAL OF PHARMACOLOGY Volume: 40 Pages: 82-82
Meeting Abstract: 162 Published: OCT 2008
25.
Hypoglycemic effect of holarrhena
antidysenterica [HA] seed powder in streptozotocin induced diabetic rats
Kumar S.; Gari M.; Sharma J. - INDIAN JOURNAL OF
PHARMACOLOGY Volume: 40 Pages: 199-199
Meeting Abstract: 569 Published: OCT 2008
26.
Development and validation of a visible
absorption densitometry method for quantitation of conessine in Holarrhena
antidysenterica (Kurchi)
Patel Rakesh K.; Prajapati Arun M. - JOURNAL OF AOAC
INTERNATIONAL Volume: 91 Issue: 2 Pages:
339-343 Published: MAR-APR 2008
27.
High frequency in vitro propagation of
Holarrhena antidysenterica from nodal buds of mature tree
Mallikarjuna K.; Rajendrudu G. - BIOLOGIA
PLANTARUM Volume: 51 Issue: 3 Pages: 525-529
DOI: http://dx.doi.org/10.1007/ s10535-007-0112-y
Published: SEP 2007
28.
Steroidal alkaloids from Holarrhena
antidysenterica (L.) WALL
Kumar Neeraj; Singh Bikram; Bhandari Pamita; et al. - CHEMICAL
& PHARMACEUTICAL BULLETIN Volume: 55 Issue: 6
Pages: 912-914 DOI: http://dx.doi.org/10.1248/cpb. 55.912
Published: JUN 2007
29.
Phytotoxic effects of Cu, Zn, Cd and Pb on in
vitro regeneration and concomitant protein changes in Holarrhena
antidysenterica
Agrawal V; Sharma K - BIOLOGIA PLANTARUM Volume:
50 Issue: 2 Pages: 307-310 DOI:
http://dx.doi.org/10.1007/ s10535-006-0027-z Published: JUN 2006
30.
In vitro clonal propagation of Holarrhena
antidysenterica (L.) wall. Through nodal explants from mature trees
Kumar R; Sharma K; Agrawal V - IN VITRO CELLULAR & DEVELOPMENTAL
BIOLOGY-PLANT Volume: 41 Issue: 2 Pages:
137-144 DOI: http://dx.doi.org/10.1079/ IVP2004624
Published: MAR-APR 2005
31.
Antibacterial and antidiarrhoeal effects of
alkaloids of Holarrhena antidysenterica WALL.
Kavitha D; Shilpa P N; Devaraj S Niranjali - Indian journal
of experimental biology Volume: 42 Issue: 6
Pages: 589-94 Published: 2004-Jun
32.
Chromosome stability in culture derived plants
of Holarrhena antidysenterica Wall. and study of differentiating tissues using
SEM
Raha S; Roy SC - CARYOLOGIA Volume: 56
Issue: 3 Pages: 329-335 Published: JUL-SEP
2003
33.
Efficient plant regeneration in Holarrhena
antidysenterica Wall., from shoot segment-derived callus
Raha S; Roy SC - IN VITRO CELLULAR & DEVELOPMENTAL
BIOLOGY-PLANT Volume: 39 Issue: 2 Pages:
151-155 DOI: http://dx.doi.org/10.1079/ IVP2002383
Published: MAR-APR 2003
34.
Simple and rapid TLC method for identification
of Holarrhena antidysenterica Wall. bark and its substituent Wrightia tinctoria
R. Br. bark
Lalla JK; Hamrapurkar PD; Parikh MK - JPC-JOURNAL OF PLANAR
CHROMATOGRAPHY-MODERN TLC Volume: 15 Issue: 3
Pages: 226-229 DOI: http://dx.doi.org/10.1556/JPC. 15.2002.3.14
Published: MAY-JUN 2002
35.
Alcohol concentration in the preparation of
mother tinctures of vegetable origin. The example of Holarrhena
antidysenterica.
Nandi M - Homeopathy : the journal of the Faculty of
Homeopathy Volume: 91 Issue: 2 Pages: 85-8
DOI: http://dx.doi.org/10.1054/ homp.2002.0006
Published: 2002-Apr
36.
A new sterol from Holarrhena antidysenterica
seeds
Kumar A; Ali M - INDIAN JOURNAL OF CHEMISTRY SECTION
B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY Volume: 40
Issue: 12 Pages: 1282-1284 Published: DEC
2001
37.
High frequency shoot regeneration from nodal and
shoot tip explants in Holarrhena antidysenterica L.
Ahmed G; Roy P K; Mamun A N - Indian journal of experimental
biology Volume: 39 Issue: 12 Pages: 1322-4
Published: 2001-Dec
38.
In vitro plant regeneration in Holarrhena
antidysenterica Wall., through high-frequency axillary shoot proliferation
Raha S; Roy SC - IN VITRO CELLULAR & DEVELOPMENTAL
BIOLOGY-PLANT Volume: 37 Issue: 2 Pages:
232-236 Published: MAR-APR 2001
39.
A new steroidal alkaloid from the seeds of
Holarrhena antidysenterica.
Kumar A; Ali M - Fitoterapia Volume: 71
Issue: 2 Pages: 101-4 DOI:
http://dx.doi.org/10.1016/ S0367-326X(99)00111-2 Published: 2000-Apr
40.
HYPOTENSIVE CONSTITUENTS FROM THE BARK OF
HOLARRHENA-PUBESCENS (HOLARRHENA-ANTIDYSENTERICA)
SIDDIQUI BS; USMANI SB; BEGUM S; et al. - HETEROCYCLES Volume:
41 Issue: 2 Pages: 267-276 Published: FEB 1
1995
41.
ALKALOIDAL CONSTITUENTS OF THE BARK OF
HOLARRHENA ANTIDYSENTERICA
BEGUM S; USMANI SB; SIDDIQUI BS; et al. - HETEROCYCLES Volume:
36 Issue: 4 Pages: 717-723 Published: APR 1
1993
42.
Alkaloid production by plant cell suspension
cultures of Holarrhena antidysenterica: I. Effect of major nutrients.
Panda A K; Mishra S; Bisaria V S - Biotechnology and
bioengineering Volume: 39 Issue: 10 Pages:
1043-51 DOI: http://dx.doi.org/10.1002/bit. 260391008
Published: 1992-Apr-25
43.
Alkaloid production by plant cell cultures of
Holarrhena antidysenterica: II. Effect of precursor feeding and cultivation in
stirred tank bioreactor.
Panda A K; Bisaria V S; Mishra S - Biotechnology and
bioengineering Volume: 39 Issue: 10 Pages:
1052-7 DOI: http://dx.doi.org/10.1002/bit. 260391009
Published: 1992-Apr-25
44.
Quantitative estimation of Holarrhena antidysenterica
bark total alkaloids in crude drugs and in the body fluids of man and rat.
Dwivedi R K; Sharma R K - Journal of
ethnopharmacology Volume: 30 Issue: 1 Pages:
75-89 DOI: http://dx.doi.org/10.1016/ 0378-8741(90)90018-O
Published: 1990-Aug
45.
Alkaloids in the tissue culture of Holarrhena
antidysenterica.
Dohnal B; Miedzobrodzki J; Wlodarczyk B - Acta poloniae
pharmaceutica Volume: 47 Issue: 1-2 Pages:
71-3 Published: 1990
46.
Clinical studies on amoebiasis and giardiasis
evaluating the efficacy of kutaja (holarrhena antidysenterica) in entamoeba
histolytica cyst passers.
Singh K P - Ancient science of life Volume: 5
Issue: 4 Pages: 228-31 Published: 1986-Apr
47.
Studies on Holarrhena antidysenterica wall. 1.
Botany, medico-ethnobotany and distribution.
Kaul M K; Atal C K - Journal of
ethnopharmacology Volume: 8 Issue: 3 Pages:
349-56 DOI: http://dx.doi.org/10.1016/ 0378-8741(83)90074-0
Published: 1983-Sep
48.
Side effects of a traditional indigenous
drug-Kutaja (Holarrhena antidysenterica)
Chaturvedi G N; Singh K P - Indian journal of physiology and
pharmacology Volume: 27 Issue: 3 Pages:
255-6 Published: 1983 Jul-Sep
49.
[Alkaloidal steroids-C. Holantosines A and B,
new amino-glyco-steroids isolated from leaves of Holarrhena
antidysenterica(Roxb.). Wall. (Apocynacees)].
Janot M M; Khuong-Huu Q; Monneret C; et al. - Tetrahedron Volume:
26 Issue: 7 Pages: 1695-709 DOI:
http://dx.doi.org/10.1016/ S0040-4020(01)93020-0 Published: 1970-Apr
50.
The seasonal variation of alkaloids in different
parts of Holarrhena antidysenterica Wall. and the alkaloid content in the bark
at different ages. Part 1.
DUTTA A T; GHOSH B K; GUPTA J C - The Indian journal of
medical research Volume: 38 Issue: 4 Pages:
467-72 Published: 1950-Oct
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