Thursday, August 23, 2012

Fagonia cretica Tulganari Dhamaasaa Chittigava


Fagonia cretica L.
Synonyms: Fagonia deflexa Moench, Fagonia elongata Salisb., Fagonia erecta Mill., Fagonia forskalii Pfund, Fagonia hispanica L., Fagonia virens Coss. ex T.Anderson, Fagonia viscosa Hochst. ex Boiss.

Correct name for Indian sp. is Fagonia schweifurthii Hadidi. F. bruguieri DC. is not a synonym of F. cretica, (Indian Medicinal Plants an Illustrated Dictionary)
according to CDRI.)
Sanskrit: Dhanvayasah, Duhsparsha, Duralambha, Virupa, Duralabha, Ushtrabhaksha
Bengali: Duralabha
English: Khorasan thorn
Gujrati: Dhamaaso
Hindi: Damahan, Dhamaasa, Hinguaa, Dhanhare
Malayalam: Kodittuva
Marathi: Dhamaasaa
Punjabi: Dama, Dhamah, Dhamaha
Tamil: Tulganari
Telugu: Chittigava, Gilaregati
Unani: Dhamaasaa

Ayurvedic uses: Daha, Grahani, Gulma, Jvara, Kasa, Kushta, Prameha, Raktapitta, Vatarakta, Visarpa, Atisara, Visama jvara, Trishna, Moha, Murccha, Madaroga,Rakatavikara, Bharama, Chardi, Mutraghata.
Astringent, antiseptic, blood-purifier and febrifuge. Applied to abscesses, scrofulous glands and wounds; also given as a prophylactic against smallpox. Bark—used for dermatosis Extract of aerial parts—antiviral, antiamphetaminic, spasmogenic. Plant ash—given to children suffering from anaemia. 

Fagonia cretica herbal tea arrested the growth of cancer cells within five hours of application and caused them to die within 24 hours.   Source: Times of India Dt.23 Aug. 2012

35 Published articles of Fagonia cretica
1.    An Aqueous Extract of Fagonia cretica Induces DNA Damage, Cell Cycle Arrest and Apoptosis in Breast Cancer Cells via FOXO3a and p53 Expression
Lam, Matt; Carmichael, Amtul R.; Griffiths, Helen R. - PLOS ONE  Volume: 7   Issue: 6     Article Number: e40152   DOI: http;//dx.doi.org/10.1371/journal.pone.0040152   Published: JUN 27 2012
2.    An Aqueous Extract of Fagonia cretica Induces DNA Damage, Cell Cycle Arrest and Apoptosis in Breast Cancer Cells via FOXO3a and p53 Expression.
Lam, Matt; Carmichael, Amtul R; Griffiths, Helen R - PloS one  Volume: 7   Issue: 6   Pages: e40152   Published: 2012 (Epub 2012 Jun 27)
3.    Antihaemorrhagic potentials of Fagonia cretica against Naja naja karachiensis (black Pakistan cobra) venom
Razi, Muhammad Tahir; Bin Asad, Muhammad Hassham Hassan; Khan, Taous; et al. - NATURAL PRODUCT RESEARCH  Volume: 25   Issue: 20   Pages: 1902-1907   DOI: http;//dx.doi.org/10.1080/14786419.2010.490785   Published: 2011
4.    Phytochemical screening and antimicrobial activity of Fagonia cretica plant extracts against selected microbes.
Sajid, B.; Alia, E.; Rizwana, K.; et al. - Journal of Pharmacy Research  Volume: 4   Issue: 4   Pages: 962-963   Published: 2011
5.    Antimicrobial Constituents from Fagonia cretica
Anjum, Muhammad Imran; Ahmed, Ejaz; Jabbar, Abdul; et al. - JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN  Volume: 29   Issue: 6   Pages: 634-639   Published: DEC 2007
6.    Cytotoxic and antitumor potential of Fagonia cretica L.
Ahsan Hussain; Muhammad Zia; Bushra Mirza - Turkish Journal of Biology  Volume: 31   Issue: 1   Pages: 19-24   Published: 2007
7.    Cytotoxic and antitumor potential of Fagonia cretica L.
Hussain, Ahsan; Zia, Muhammad; Mirza, Bushra - Turkish Journal of Biology  Volume: 31   Issue: 1   Pages: 19-24   Published: 2007
8.    Antimicrobial efficacy of methanolic extracts of Fagonia cretica
Thetwar, LK; Thakur, AS; Shrivastava, S; et al. - ASIAN JOURNAL OF CHEMISTRY  Volume: 18   Issue: 1   Pages: 743-744   Published: JAN-MAR 2006
9.    Effect of Rubia cordifolia, Fagonia cretica linn, and Tinospora cordifolia on free radical generation and lipid peroxidation during oxygen-glucose deprivation in rat hippocampal slices
Rawal, A; Muddeshwar, M; Biswas, S - BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS  Volume: 324   Issue: 2   Pages: 588-596   DOI: http;//dx.doi.org/10.1016/j.bbrc.2004.09.094   Published: NOV 12 2004
10.    Rubia cordifolia, Fagonia cretica linn and Tinospora cordifolia exert neuroprotection by modulating the antioxidant system in rat hippocampal slices subjected to oxygen glucose deprivation.
Rawal, Avinash K; Muddeshwar, Manohar G; Biswas, Saibal K - BMC complementary and alternative medicine  Volume: 4   Pages: 11   DOI: http;//dx.doi.org/10.1186/1472-6882-4-11   Published: 2004 Aug 13
11.    Effects of Fagonia cretica L. constituents on various haematological parameters in rabbits.
Asif Saeed, M; Wahid Sabir, A - Journal of ethnopharmacology  Volume: 85   Issue: 2-3   Pages: 195-200   DOI: http;//dx.doi.org/10.1016/S0378-8741(02)00365-3   Published: 2003-Apr
12.    Effects of Fagonia cretica L. constituents on various haematological parameters in rabbits
Saeed, MA; Sabir, AW - JOURNAL OF ETHNOPHARMACOLOGY  Volume: 85   Issue: 2-3   Pages: 195-200   DOI: http;//dx.doi.org/10.1016/S0378-8741(02)00365-3   Published: APR 2003
13.    Autecological studies on Fagonia cretica, L. affecting its active constituent.
Emam, S. S.; Tolba, I. A. M. - Annals of Agricultural Science, Moshtohor  Volume: 40   Issue: 2   Pages: 1183-1202   Published: 2002
14.    Production of endogenous ascorbic acid from tissue cultures of Fagonia cretica Linn.
Kapoor, B. B. S. - Journal of Phytological Research  Volume: 15   Issue: 1   Pages: 111-112   Published: 2002
15.    Further saponins from Fagonia cretica
Abdel-Khalik, SM; Miyase, T; Melek, FR; et al. - PHARMAZIE  Volume: 56   Issue: 3   Pages: 247-250   Published: MAR 2001
16.    Triterpenoid saponins from Fagonia cretica.
Abdel Khalik, S M; Miyase, T; El-Ashaal, H A; et al. - Phytochemistry  Volume: 54   Issue: 8   Pages: 853-9   Published: 2000-Aug
17.    Triterpenoid saponins from Fagonia cretica
Khalik, SMA; Miyase, T; El-Ashaal, HA; et al. - PHYTOCHEMISTRY  Volume: 54   Issue: 8   Pages: 853-859   DOI: http;//dx.doi.org/10.1016/S0031-9422(00)00168-0   Published: AUG 2000
18.    Trace elements in indigenous medicinal plants (Rhazya stricta, Vinca rosea and Fagonia cretica)
Fatima, Kaneez; Shirin, Khaula; Ali Kalhoro, Mahboob; et al. - Pakistan Journal of Scientific and Industrial Research  Volume: 42   Issue: 4   Pages: 182-183   Published: Aug., 1999
19.    Trace elements in indigenous medicinal plants ( Rhazya stricta, Vinca rosea and Fagonia cretica).
Kaneez Fatima; Khaula Shirin; Kalhoro, M. A.; et al. - Pakistan Journal of Scientific and Industrial Research  Volume: 42   Issue: 4   Pages: 182-183   Published: 1999
20.    Effects of Fagonia cretica L. constituents on various endocrinological parameters in rabbits
Saeed, M. Asif; Khan, Zaheer-ul-Din; Sabir, A. W. - Turkish Journal of Biology  Volume: 23   Issue: 2   Pages: 187-197   Published: 1999
21.    Biological properties of saponin mixtures of Fagonia cretica and Fagonia mollis
El-Shabrawy, O. A.; El-Gindi, K. O.; Melek, F. R.; et al. - Fitoterapia  Volume: 68   Issue: 3   Pages: 219-222   Published: 1997
22.    Investigation on fagonia cretica -its effect on hormonal profile and immunomodulation in rats.
Abirami, V; Khosa, R L; Dhar, S K; et al. - Ancient science of life  Volume: 15   Issue: 4   Pages: 259-63   Published: 1996-Apr
23.    New saponins from Fagonia cretica
Melek, F. R.; Abdel-Khalik, S. M.; Miyase, Toshio; et al. - Fitoterapia  Volume: 65   Issue: 4   Pages: 363-366   Published: 1994
24.    Toxicological study of the new molluscicidal plants: Fagonia cretica and Agave filifera
Ebeid, Fatma A.; Badawy, Afkar A.; Mostafa, Ahmed M.; et al. - Egyptian Journal of Bilharziasis  Volume: 13   Issue: 1-2   Pages: 171-179   Published: 1991 (1992)
25.    REMOVAL OF SEED DORMANCY BY GA-3 IN FAGONIA-CRETICA L. A TYPICAL INDIAN DESERT SPECIES
MOHAMMED S; SEN D N - Indian Botanical Reporter  Volume: 7   Issue: 1-2   Pages: 95-96   Published: 1988
26.    EFFECT OF FAGONIA-CRETICA ON SERUM PROLACTIN THYROTROPIN TSH THYROXINE T-4 AND CORTISOL LEVELS IN RABBITS
RASHEED A; JANBAZ K H; KHAN S M; et al. - Pakistan Veterinary Journal  Volume: 8   Issue: 3   Pages: 114-118   Published: 1988
27.    Molluscicidal activity of Fagonia cretica and Atriplex leucoclada.
Shoeb, H A; el-Emam, M A; Saad, A M; et al. - Journal of the Egyptian Society of Parasitology  Volume: 17   Issue: 2   Pages: 539-46   Published: 1987-Dec
28.    WATER-SOLUBLE PROTEIN FROM FAGONIA-CRETICA LINN
SHAUKAT, GA; MALIK, MA; AHMAD, MS - PAKISTAN JOURNAL OF BOTANY  Volume: 13   Issue: 1   Pages: 99-101   Published: 1981
29.    THE ISOLATION AND IDENTIFICATION OF ACTIVE PRINCIPLES FROM FAGONIA-CRETICA IDENTIFICATION OF FATTY-ACIDS BY THIN LAYER CHROMATOGRAPHY
ARAYNE M S; SAIFY Z S; NAIM Z - Journal of Science (Karachi)  Volume: 4   Issue: (SUPPL)   Pages: 105-108   Published: 1976
30.    CHEMICAL INVESTIGATION OF FAGONIA-CRETICA
IYER A; JOSHI B C - Herba Polonica  Volume: 21   Issue: 4   Pages: 420-423   Published: 1975
31.    ISOLATION OF OLEANOLIC-ACID FROM FAGONIA-CRETICA-D
RIMPLER H; RIZK A M - Phytochemistry (Oxford)  Volume: 8   Issue: 11   Pages: 2269   DOI: http;//dx.doi.org/10.1016/S0031-9422(00)88196-0   Published: 1969
32.    INTRAINDIVIDUAL NUMERICAL CHROMOSOME INSTABILITY IN FAGONIA CRETICA L
BAQUAR, SR - GENETICA IBERICA  Volume: 19   Issue: 1-2   Pages: 99-&   Published: 1967
33.    TRI TERPENOIDS II ANOTHER SAPOGENIN FROM FAGONIA-CRETICA-D ZYGOPHYLLACEAE-D
ALI M A; HAMEED Z - Pakistan Journal of Scientific and Industrial Research  Volume: 10   Issue: 2   Pages: 140-141   Published: 1967
34.    CHEMICAL EXAMINATION OF PLANT FAGONIA CRETICA LINN .2.
TANDON, SP; TIWARI, KP - PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES INDIA SECTION A-PHYSICAL SCIENCES  Volume: 37   Pages: 173-&   Part: Part 2   Published: 1967
35.    Description de deux Zoocecidies nouvelles sur Fagonia cretica L.
Houard, C. - Bulletin de la Societe Entomologique de France  Pages: pp. 44-46   Published: 1901
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antidysenterica Holarrhena pubescens Holoptelea integrifolia Hosta plantaginea Hoya carnosa Hydrocotyle sibthorpioides Hydrolea zeylanica Hygrophila auriculata Hygrophila polysperma Hygrophila schulli Hylocereus undatus Hymenocallis speciosa Hymenodictyon orixense Hyoscyamus niger Hypericum dyeri Hypericum elodeoides Hypericum oblongifolium Hyptis suaveolens Ilex dipyrena Impatiens balsamina Impatiens bracteata Impatiens racemosa Indigofera aspalathoides Indigofera astragalina Indigofera glabra Ipomoea alba Ipomoea aquatica Ipomoea marginata Isodon rugosus Ixeris polycephala Jacaranda mimosifolia Jacquemontia pentantha Jasminum auriculatum Jasminum multiflorum Jatropha curcas Jatropha gossypifolia Juncus thomsonii Justicia adhatoda Justicia brandegeeana Justicia carnea Justicia gendarussa Justicia pubigera Kalanchoe blossfeldiana Kallstroemia pubescens Koelreuteria elegans Koelreuteria paniculata Koenigia delicatula Kopsia fruticosa Kydia calycina Kyllinga brevifolia Lablab purpureus 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Ruellia tuberosa Rumex dentatus Rumex hastatus Rungia pectinata Saccharum officinarum Saccharum spontaneum Salix denticulata Salix tetrasperma Salvadora persica Salvia involucrata Salvia miltiorrhiza Salvia nubicola Salvia splendens Sambucus canadensis Sambucus mexicana Sambucus nigra Santalum album Sapindus saponaria Saussurea auriculata Saussurea candicans Saussurea obvallata Scadoxus multiflorus Scutellaria baicalensis Scutellaria grossa Scutellaria repens Sedum oreades Semecarpus anacardium Senna auriculata Senna occidentalis Senna siamea Senna sophera Sesbania bispinosa Sesbania grandiflora Seseli diffusum Sesuvium portulacastrum Setaria verticillata Shorea robusta Sida cordata Sida cordifolia Sida retusa Sida spinosa Sideritis hirsuta Silybum marianum Smithia ciliata Solanum chrysotrichum Solanum erianthum Solanum jasminoides Solanum melongena Solanum nigrum Solanum sisymbriifolium Solanum surattense Solanum torvum Solanum tuberosum Solanum villosum Sonchus oleraceus Soymida febrifuga Sphaeranthus amaranthoides Sphenoclea zeylanica Spiranthes australis Spiranthes sinensis Spondias pinnata Stellaria media Stellera chamaejasme Stephania japonica Sterculia alata Sterculia foetida Sterculia villosa Stereospermum tetragonum Stevia rebaudiana Striga asiatica Strophanthus boivinii Strychnos minor Strychnos nux-vomica Strychnos potatorum Suaeda maritima Suregada multiflora Swertia angustifolia Swertia bimaculata Swertia cordata Swertia paniculata Swietenia macrophylla Swietenia mahagoni Syzygium alternifolium Syzygium aromaticum Syzygium cumini Syzygium jambos Syzygium samarangense Tabebuia aurea Tabebuia avellanedae Talinum portulacifolium Tamarindus indica Taxus baccata Tecoma castanifolia Tephrosia calophylla Tephrosia purpurea Teramnus labialis Terminalia alata Terminalia catappa Terminalia chebula Terminalia elliptica Terminalia pallida Teucrium botrys Teucrium royleanum Thalictrum foliolosum Thespesia populnea Thunbergia erecta Thunbergia fragrans Thunbergia grandiflora Thymus linearis Tiliacora acuminata Tiliacora racemosa Tinospora cordifolia Tinospora crispa Tinospora sinensis Toona ciliata Trewia nudiflora Tribulus terrestris Trichodesma indicum Trichosanthes cucumerina Trichosanthes palmata Trichosanthes tricuspidata Trifolium repens Trigonella foenum-graecum Triumfetta rhomboidea Tylophora indica Uraria picta Urena lobata Urena sinuata Urginea coromandeliana Vachellia horrida Valeriana jatamansi Vanda tessellata Veronica serpyllifolia Viburnum coriaceum Vicia bakeri Vicia faba Vicia sativa Vigna radiata Vigna unguiculata Vinca rosea Viola rupestris Viscum album Vitex negundo Vitis vinifera Withania somnifera Wrightia tinctoria Wulfeniosis amherstiana Zamia furfuracea Ziziphus jujuba Ziziphus mauritiana
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