Salvia miltiorrhiza BungeFamily: Lamiaceae
- English: redroot sage, Chinese salvia
- German: Rotwurzel-Salbei
- Korea: 단삼
- Macedonian: Даншен
- Japanese: 丹参
- Thai: ตังเซียม
- Chinese: 山参
- Vietnamese: Đan sâm
Description: Plants perennial. Taproot thickened, succulent, scarlet outside. Stems erect, 40-80 cm tall, villous, much branched. Leaves simple to odd-pinnate; petiole 1.3-7.5 cm, densely retrorse villous, petiolule 2-14 mm; leaflets 3-5(-7), 1.5-8 × 1-4 cm, blades or leaflets circular to broadly lanceolate, pilose, densely so abaxially, margin crenate, apex acute to acuminate. Inflorescences densely villous or glandular villous; verticillasters 6- to many flowered, basally remote, apically crowded, in terminal or axillary racemes 4.5-17 cm; bracts lanceolate. Pedicel 3-4 mm. Calyx campanulate, purplish, ca. 1.1 cm, slightly dilated after anthesis, sparsely villous or glandular villous, margin ciliate; upper lip entire, triangular, ca. 4 × 8 mm, apex 3-mucronate; lower lip almost as long as upper, 2-toothed. Corolla purple-blue or white, 2-2.7 cm, glandular pubescent, densely so on upper lip; tube imperfectly fine pilose annulate inside, exserted, shorter than limb, 2 mm wide at base, to 8 mm wide at throat; upper lip 1.2-1.5 cm, falcate; lower lip shorter, middle lobe ca. 5 × to 10 mm, 2-lobulate; lateral lobes rounded, ca. 3 mm wide. Filaments 3.5-4 mm; connectives 1.7-2 cm. Style much exserted. Nutlets ellipsoid, ca. 3.2 × 1.5 mm.
Uses: Case reports and animal studies have indicated that concomitant use of Chinese salvia and warfarin slows the metabolism and increases blood levels of warfarin. A human study indicated no interaction between Chinese salvia and theophylline. One animal study indicated that Chinese salvia can decrease plasma levels of diazepam. Inhibition of platelet aggregation and a d ecrease in blood viscosity have been reported in animal studies and in vitro A reference text on traditional Chinese medicine indicates that Chinese salvia is contraindicated in pregnancy. [American Herbal Products Associations Botanical Safety Handbook]
Chinese salvia is one of the primary botanicals used in traditional Chinese medicine for invigorating circulation and dissolving blood clots. It is commonly applied in the treatment of gynecological conditions and cardiovascular disease. A variety of processing techniques are applied to Salvia that can result in minor to significant changes in the microscopic structure of the material. These include dry-fried salvia (chao dan shen), mix fried with wine (jiu zhi dan shen), and charred salvia (dan shen tan). Chinese salvia is not readily subject to adulteration. [American Herbal Pharmacopoeia: Botanical Pharmacognosy—Microscopic Characterization of Botanical Medicines]
The dried root of danshen (Chinese salvia) is traditionally used in Chinese medicine for cardiovascular and cerebrovascular diseases, specifically angina pectoris, hyperlipidaemia and acute ischaemic stroke, but also palpitations, hypertension, thrombosis and menstrual problems. It is also used as an anti-inflammatory and for the treatment of cancer and liver disease. [Stockley's Herbal Medicines Interactions]
Root - Anticoagulant • lowers blood pressure • sedative • Tonic for heart and circulation [Herbal Remedies]
Salvia miltiorrhiza (dan shen) is used in traditional Chinese medicine as a circulatory stimulant, sedative, and cooling agent. It may also be valuable as an antianginal drug, because it has been shown to dilate coronary arteries in all concentrations. [Medical Hrebalism - The Science and Practice of Herbal Medicine]
The dried root of danshen (Chinese salvia) is traditionally used in Chinese medicine for cardiovascular and cerebrovascular diseases, specifically angina pectoris, hyperlipidaemia and acute ischaemic stroke, but also palpitations, hypertension, thrombosis and menstrual problems. It is also used as an anti-inflammatory and for the treatment of cancer and liver disease. [Stockley's Herbal Medicines Interactions]
Root - Anticoagulant • lowers blood pressure • sedative • Tonic for heart and circulation [Herbal Remedies]
Salvia miltiorrhiza (dan shen) is used in traditional Chinese medicine as a circulatory stimulant, sedative, and cooling agent. It may also be valuable as an antianginal drug, because it has been shown to dilate coronary arteries in all concentrations. [Medical Hrebalism - The Science and Practice of Herbal Medicine]
About 1000 articles published on Salvia miltiorrhiza. There are more than 4000 patents on this plant.
1. Zhang, T., et al., In vitro and in silico perspectives on estrogenicity of tanshinones from Salvia miltiorrhiza. Food Chemistry, 2019. 270: p. 281-286.
2. Zhu, L., et al., Improving the Classification Accuracy for Near-Infrared Spectroscopy of Chinese Salvia miltiorrhiza Using Local Variable Selection. Journal of Analytical Methods in Chemistry, 2018.
3. Zhou, Z., et al., CRISPR/Cas9-mediated efficient targeted mutagenesis of RAS in Salvia miltiorrhiza. Phytochemistry, 2018. 148: p. 63-70.
4. Zhou, L.S., K. Tang, and S.X. Guo, The Plant Growth-Promoting Fungus (PGPF) Alternaria sp A13 Markedly Enhances Salvia miltiorrhiza Root Growth and Active Ingredient Accumulation under Greenhouse and Field Conditions. International Journal of Molecular Sciences, 2018. 19(1).
5. Zhang, Y., et al., Genomic survey of bZIP transcription factor genes related to tanshinone biosynthesis in Salvia miltiorrhiza. Acta Pharmaceutica Sinica B, 2018. 8(2): p. 295-305.
6. Zhang, X.-D., et al., Chemotaxonomic variation in secondary metabolites contents and their correlation between environmental factors in Salvia miltiorrhiza Bunge from natural habitat of China. Industrial Crops and Products, 2018. 113: p. 335-347.
7. Zhang, X., et al., Bivariate Correlation Analysis of the Chemometric Profiles of Chinese Wild Salvia miltiorrhiza Based on UPLC-Qqq-MS and Antioxidant Activities. Molecules, 2018. 23(3).
8. Zhang, W. and J. Dong, Effectiveness of Radix astragali and Salvia miltiorrhiza injection in treatment of skeletal muscle injury of aerobics athletes. Pakistan Journal of Pharmaceutical Sciences, 2018. 31(4): p. 1767-1771.
9. Zhang, J., et al., Minor compounds of the high purity salvianolic acid B freeze-dried powder from Salvia miltiorrhiza and antibacterial activity assessment. Natural Product Research, 2018. 32(10): p. 1198-1202.
10. Zhai, X., et al., Endophyte Chaetomium globosum D38 Promotes Bioactive Constituents Accumulation and Root Production in Salvia miltiorrhiza. Frontiers in Microbiology, 2018. 8.
11. Yu, T., et al., Computational insights into beta-site amyloid precursor protein enzyme 1 (BACE1) inhibition by tanshinones and salvianolic acids from Salvia miltiorrhiza via molecular docking simulations. Computational Biology and Chemistry, 2018. 74: p. 273-285.
12. Yu, J., et al., Diethyl Blechnic, a Novel Natural Product Isolated from Salvia miltiorrhiza Bunge, Inhibits Doxorubicin-Induced Apoptosis by Inhibiting ROS and Activating JNK1/2. International Journal of Molecular Sciences, 2018. 19(6).
13. Yu, H., et al., Transcriptional Profiles of SmWRKY Family Genes and Their Putative Roles in the Biosynthesis of Tanshinone and Phenolic Acids in Salvia miltiorrhiza. International Journal of Molecular Sciences, 2018. 19(6).
14. You, H., et al., Promotion of phenolic compounds production in Salvia miltiorrhiza hairy roots by six strains of rhizosphere bacteria. Engineering in Life Sciences, 2018. 18(3): p. 160-168.
15. Xu, Y., et al., Veratrum nigrum inhibits the estrogenic activity of salvia miltiorrhiza bunge in vivo and in vitro. Phytomedicine, 2018. 43: p. 68-77.
16. Xu, W.J., et al., Identifying the molecular targets of Salvia miltiorrhiza (SM) in ox-LDL induced macrophage-derived foam cells based on the integration of metabolomics and network pharmacology. Rsc Advances, 2018. 8(7): p. 3760-3767.
17. Xiang, X., et al., Simultaneous determination of polysaccharides and 21 nucleosides and amino acids in different tissues of Salvia miltiorrhiza from different areas by UV-visible spectrophotometry and UHPLC with triple quadrupole MS/MS. Journal of Separation Science, 2018. 41(5): p. 996-1008.
18. Wei, T., et al., Comparative Transcriptome Analyses Reveal Potential Mechanisms of Enhanced Drought Tolerance in Transgenic Salvia Miltiorrhiza Plants Expressing AtDREB1A from Arabidopsis. International Journal of Molecular Sciences, 2018. 19(3).
19. Wang, Y.-L., et al., Screening and Characterizing Tyrosinase Inhibitors from Salvia miltiorrhiza and Carthamus tinctorius by Spectrum-Effect Relationship Analysis and Molecular Docking. Journal of Analytical Methods in Chemistry, 2018.
20. Wang, X., et al., Antitumor effect and molecular mechanism of antioxidant polysaccharides from Salvia miltiorrhiza Bunge in human colorectal carcinoma LoVo cells. International Journal of Biological Macromolecules, 2018. 108: p. 625-634.
21. Wang, L., et al., Cardio-protection of ultrafine granular powder for Salvia miltiorrhiza Bunge against myocardial infarction. Journal of Ethnopharmacology, 2018. 222: p. 99-106.
22. Wang, H., et al., Transcriptome Analyses from Mutant Salvia miltiorrhiza Reveals Important Roles for SmGASA4 during Plant Development. International Journal of Molecular Sciences, 2018. 19(7).
23. Uto, T., et al., Antiproliferative activity and apoptosis induction by trijuganone C isolated from the root of Salvia miltiorrhiza Bunge (Danshen). Phytotherapy Research, 2018. 32(4): p. 657-666.
24. Tang, H., D. Zhao, and Z. Xue, Exploring the interaction between Salvia miltiorrhiza and alpha-glucosidase: insights from computational analysis and experimental studies. Rsc Advances, 2018. 8(44): p. 24701-24710.
25. Sun, Q., et al., Effect of La3+ on seed germination and seedling growth of Salvia miltiorrhiza. Journal of Rare Earths, 2018. 36(8): p. 898-902.
26. Shen, Y., et al., Rapid profiling of polymeric phenolic acids in Salvia miltiorrhiza by hybrid data-dependent/targeted multistage mass spectrometry acquisition based on expected compounds prediction and fragment ion searching. Journal of Separation Science, 2018. 41(8): p. 1888-1895.
27. Peng, Y., et al., Salvia Miltiorrhiza Ameliorates Liver Fibrosis by Activating Hepatic Natural Killer Cells in Vivo and in Vitro. Frontiers in Pharmacology, 2018. 9.
28. Pei, T., et al., SmJAZ8 acts as a core repressor regulating JA-induced biosynthesis of salvianolic acids and tanshinones in Salvia miltiorrhiza hairy roots. Journal of Experimental Botany, 2018. 69(7): p. 1663-1678.
29. Pan, X.-G., et al., An unusual racemic C-12-norabietane diterpene and a new abietane diterpene alkaloid from Salvia miltiorrhiza Bunge. Fitoterapia, 2018. 125: p. 240-244.
30. Mannelli, L.D.C., et al., Tanshinones from Salvia miltiorrhiza Bunge revert chemotherapy-induced neuropathic pain and reduce glioblastoma cells malignancy. Biomedicine & Pharmacotherapy, 2018. 105: p. 1042-1049.
31. Lobina, C., et al., Anxiolytic effect of an extract of Salvia miltiorrhiza roots in rats. Journal of the Chinese Medical Association, 2018. 81(5): p. 390-397.
32. Liu, L., et al., Salvia castanea Hairy Roots are More Tolerant to Phosphate Deficiency than Salvia miltiorrhiza Hairy Roots Based on the Secondary Metabolism and Antioxidant Defenses. Molecules, 2018. 23(5).
33. Liu, H., et al., Anti-inflammatory activities and potential mechanisms of phenolic acids isolated from Salvia miltiorrhiza f. alba roots in THP-1 macrophages. Journal of Ethnopharmacology, 2018. 222: p. 201-207.
34. Li, Z.-m., S.-w. Xu, and P.-q. Liu, Salvia miltiorrhiza Burge (Danshen): a golden herbal medicine in cardiovascular therapeutics. Acta Pharmacologica Sinica, 2018. 39(5): p. 802-824.
35. Li, S., et al., SmMYB111 Is a Key Factor to Phenolic Acid Biosynthesis and Interacts with Both SmTTG1 and SmbHLH51 in Salvia miltiorrhiza. Journal of Agricultural and Food Chemistry, 2018. 66(30): p. 8069-8078.
36. Li, L., et al., Early application of salvia miltiorrhiza at huatuojiaji points reduces incidence of post-herpetic neuralgia. International Journal of Clinical and Experimental Medicine, 2018. 11(7): p. 7216-7223.
37. Li, L., et al., Jiaji acupoint injection of salvia miltiorrhiza-extract combined with SNB affect PHN. International Journal of Clinical and Experimental Medicine, 2018. 11(2): p. 1141-1149.
38. Li, K., et al., Effective component of Salvia miltiorrhiza in promoting cardiomyogenic differentiation of human placenta-derived mesenchymal stem cells. International Journal of Molecular Medicine, 2018. 41(2): p. 962-968.
39. Li, J., C. Li, and S. Lu, Identification and characterization of the cytosine-5 DNA methyltransferase gene family in Salvia miltiorrhiza. Peerj, 2018. 6.
40. Li, J., C. Li, and S. Lu, Systematic analysis of DEMETER-like DNA glycosylase genes shows lineage-specific Smi-miR7972 involved in SmDML1 regulation in Salvia miltiorrhiza. Scientific Reports, 2018. 8.
41. Li, H., et al., The Pentatricopeptide Repeat Gene Family in Salvia miltiorrhiza: Genome-Wide Characterization and Expression Analysis. Molecules, 2018. 23(6).
42. Li, G., et al., Comparison of the chromatographic fingerprint, multicomponent quantitation and antioxidant activity of Salvia miltiorrhiza Bge. between sweating and nonsweating. Biomedical Chromatography, 2018. 32(6).
43. Li, G., X. Wang, and K.H. Row, Magnetic molecularly imprinted polymers based on silica modified by deep eutectic solvents for the rapid simultaneous magnetic-based solid-phase extraction of Salvia miltiorrhiza bunge, Glycine max (Linn.) Merr and green tea. Electrophoresis, 2018. 39(8): p. 1111-1118.
44. Lee, J.-H., et al., A novel photo-biological engineering method for Salvia miltiorrhiza-mediated fabrication of silver nanoparticles using LED lights sources and its effectiveness against Aedes aegypti mosquito larvae and microbial pathogens. Physiological and Molecular Plant Pathology, 2018. 101: p. 178-186.
45. Kishikawa, N., et al., Determination of Tanshinones in Danshen (Salvia miltiorrhiza) by High-Performance Liquid Chromatography with Fluorescence Detection after pre-Column Derivatisation. Phytochemical Analysis, 2018. 29(1): p. 112-117.
46. Kim, R., et al., Salvia miltiorrhiza enhances the survival of mesenchymal stem cells under ischemic conditions. Journal of Pharmacy and Pharmacology, 2018. 70(9): p. 1228-1241.
47. Kim, C., et al., Activation of ER Stress-Dependent miR-216b Has a Critical Role in Salvia miltiorrhiza Ethanol-Extract-Induced Apoptosis in U266 and U937 Cells. International Journal of Molecular Sciences, 2018. 19(4).
48. Jia, C., et al., Protective effect of compound Danshen (&ITSalvia miltiorrhiza&IT) dripping pills alone and in combination with carbamazepine on kainic acid-induced temporal lobe epilepsy and cognitive impairment in rats. Pharmaceutical Biology, 2018. 56(1): p. 217-224.
49. Hwang, S.H., et al., Anti-Nociceptive Effect and Standardization from Mixture of Agrimonia pilosa Ledeb and Salvia miltiorrhiza Bunge Extracts. Journal of Medicinal Food, 2018. 21(6): p. 596-604.
50. Huang, C., et al., Combination of Salvia miltiorrhiza and ligustrazine attenuates bleomycin-induced pulmonary fibrosis in rats via modulating TNF-alpha and TGF-beta. Chinese Medicine, 2018. 13.
51. Gao, H., et al., Simultaneous purification of dihydrotanshinone, tanshinone I, cryptotanshinone, and tanshinone IIA from Salvia miltiorrhiza and their anti-inflammatory activities investigation. Scientific Reports, 2018. 8.
52. Fang, Y., et al., Diverse specialized metabolism and their responses to lactalbumin hydrolysate in hairy root cultures of Salvia miltiorrhiza Bunge and Salvia castanea Diels f. tomentosa Stib. Biochemical Engineering Journal, 2018. 131: p. 58-69.
53. Deng, Y., et al., Identification and Characterization of Flavonoid Biosynthetic Enzyme Genes in Salvia miltiorrhiza (Lamiaceae). Molecules, 2018. 23(6).
54. Choi, H.G., et al., Anti-inflammatory activity of caffeic acid derivatives isolated from the roots of Salvia miltiorrhiza Bunge. Archives of Pharmacal Research, 2018. 41(1): p. 64-70.
55. Chen, Y., et al., Anti-Alzheimer's disease effect of essential oil from aerial parts of Salvia miltiorrhiza Bge. International Journal of Clinical and Experimental Medicine, 2018. 11(2): p. 641-652.
56. Chen, I.-G.J., et al., Blue light decreases tanshinone IIA content in Salvia miltiorrhiza hairy roots via genes regulation. Journal of Photochemistry and Photobiology B-Biology, 2018. 183: p. 164-171.
57. Chen, H., et al., Core Microbiome of Medicinal Plant Salvia miltiorrhiza Seed: A Rich Reservoir of Beneficial Microbes for Secondary Metabolism? International Journal of Molecular Sciences, 2018. 19(3).
58. Cao, W., et al., Transcription Factor SmWRKY1 Positively Promotes the Biosynthesis of Tanshinones in Salvia miltiorrhiza. Frontiers in Plant Science, 2018. 9.
59. Cao, J.-L., et al., Online comprehensive two-dimensional hydrophilic interaction chromatography x reversed-phase liquid chromatography coupled with hybrid linear ion trap Orbitrap mass spectrometry for the analysis of phenolic acids in Salvia miltiorrhiza. Journal of Chromatography A, 2018. 1536: p. 216-227.
60. Cai, H., et al., Protective effects of Salvia miltiorrhiza on adenine-induced chronic renal failure by regulating the metabolic profiling and modulating the NADPH oxidase/ROS/ERK and TGF-beta/Smad signaling pathways. Journal of Ethnopharmacology, 2018. 212: p. 153-165.
61. Bai, Z., et al., Coding single nucleotide polymorphisms and SmCPS1 and SmKSL1 subcellular localization are associated with tanshinone biosynthesis in Salvia miltiorrhiza Bunge roots. Acta Physiologiae Plantarum, 2018. 40(1).
62. Bai, Z., et al., The ethylene response factor SmERF6 co-regulates the transcription of SmCPS1 and SmKSL1 and is involved in tanshinone biosynthesis in Salvia miltiorrhiza hairy roots. Planta, 2018. 248(1): p. 243-255.
63. Azadniya, E. and G.E. Morlock, Bioprofiling of Salvia miltiorrhiza via planar chromatography linked to (bio)assays, high resolution mass spectrometry and nuclear magnetic resonance spectroscopy. Journal of Chromatography A, 2018. 1533: p. 180-192.
64. Zhou, Y., et al., Molecular cloning, bioinformatics analysis, and transcriptional profiling of JAZ1 and JAZ2 from Salvia miltiorrhiza. Biotechnology and Applied Biochemistry, 2017. 64(1): p. 27-34.
65. Zhou, W., et al., Comprehensive transcriptome profiling of Salvia miltiorrhiza for discovery of genes associated with the biosynthesis of tanshinones and phenolic acids. Scientific Reports, 2017. 7.
66. Zheng, J., et al., Anti-fibrotic effects of Salvia miltiorrhiza and Ligustrazine Injection on LX-2 cells involved with increased N-myc downstream-regulated gene 2 expression. Chinese Journal of Integrative Medicine, 2017. 23(12): p. 923-928.
67. Zhang, Y., et al., A Chinese patent medicine Salvia miltiorrhiza depside salts for infusion combined with conventional treatment for patients with angina pectoris: A systematic review and meta-analysis of randomized controlled trials. Phytomedicine, 2017. 25: p. 100-117.
68. Zhang, L., et al., Concentrical coils counter-current chromatography for natural products isolation: Salvia miltiorrhiza Bunge as example. Journal of Chromatography A, 2017. 1491: p. 108-116.
69. Zhang, J., et al., Overexpression of SmMYB9b enhances tanshinone concentration in Salvia miltiorrhiza hairy roots. Plant Cell Reports, 2017. 36(8): p. 1297-1309.
70. Zhang, J., et al., New depsides from the roots of Salvia miltiorrhiza and their radical scavenging capacity and protective effects against H2O2-induced H9c2 cells. Fitoterapia, 2017. 121: p. 46-52.
71. Zhang, D., et al., Oxazole-Containing Diterpenoids from Cell Cultures of Salvia miltiorrhiza and Their Anti-HIV-1 Activities. Journal of Natural Products, 2017. 80(12): p. 3242-3247.
72. Zeng, H., et al., Comparative Analysis of the Major Chemical Constituents in Salvia miltiorrhiza Roots, Stems, Leaves and Flowers during Different Growth Periods by UPLC-TQ-MS/MS and HPLC-ELSD Methods. Molecules, 2017. 22(5).
73. Yuan, T., et al., Salvianolic Acid A, a Component of Salvia miltiorrhiza, Attenuates Endothelial-Mesenchymal Transition of HPAECs Induced by Hypoxia. American Journal of Chinese Medicine, 2017. 45(6): p. 1185-1200.
74. Ye, Y.-T., et al., Apoptosis induced by the methanol extract of Salvia miltiorrhiza Bunge in non-small cell lung cancer through PTEN-mediated inhibition of PI3K/Alct pathway. Journal of Ethnopharmacology, 2017. 200: p. 107-116.
75. Yang, Y., et al., Arbuscular Mycorrhizal Fungi Regulate the Growth and Phyto-Active Compound of Salvia miltiorrhiza Seedlings. Applied Sciences-Basel, 2017. 7(1).
76. Yang, N., et al., Overexpression of SmMYC2 Increases the Production of Phenolic Acids in Salvia miltiorrhiza. Frontiers in Plant Science, 2017. 8.
77. Yan, Y.-Y., et al., Post-Marketing Safety Surveillance of the Salvia Miltiorrhiza Depside Salt for Infusion: A Real World Study. Plos One, 2017. 12(1).
78. Yan, S.-C., et al., Simultaneous Quantification of a Herbal Combination of Pueraria lobata, Salvia miltiorrhiza and Panax notoginseng by Rapid Resolution Liquid Chromatography. Natural Product Communications, 2017. 12(9): p. 1501-1506.
79. Xu, Z. and J. Song, The 2-oxoglutarate-dependent dioxygenase superfamily participates in tanshinone production in Salvia miltiorrhiza. Journal of Experimental Botany, 2017. 68(9): p. 2299-2308.
80. Xu, Y., et al., Salvia miltiorrhiza bunge increases estrogen level without side effects on reproductive tissues in immature/ovariectomized mice. Aging-Us, 2017. 9(1): p. 170-186.
81. Xing, L., et al., Bioavailability and pharmacokinetic comparison of tanshinones between two formulations of Salvia miltiorrhiza in healthy volunteers. Scientific Reports, 2017. 7.
82. Wei, W.-J., et al., Diterpenoids from Salvia miltiorrhiza and Their Immune-Modulating Activity. Journal of Agricultural and Food Chemistry, 2017. 65(29): p. 5985-5993.
83. Wei, T., et al., Modulating AtDREB1C Expression Improves Drought Tolerance in Salvia miltiorrhiza. Frontiers in Plant Science, 2017. 8.
84. Wang, Z., et al., Matrix Solid-Phase Dispersion Coupled with High-Performance Liquid Chromatography Diode Array Detection for Simultaneous Determination of Four Lipophilic Constituents from Salvia miltiorrhiza Bunge. Journal of Chromatographic Science, 2017. 55(3): p. 316-326.
85. Wang, Z., et al., Function Analysis of Caffeoyl-CoA O-Methyltransferase for Biosynthesis of Lignin and Phenolic Acid in Salvia miltiorrhiza. Applied Biochemistry and Biotechnology, 2017. 181(2): p. 562-572.
86. Wang, L., et al., Salvia miltiorrhiza: A Potential Red Light to the Development of Cardiovascular Diseases. Current Pharmaceutical Design, 2017. 23(7): p. 1077-1097.
87. Wang, K., et al., A comparative study of Danhong injection and Salvia miltiorrhiza injection in the treatment of cerebral infarction A systematic review and meta-analysis. Medicine, 2017. 96(22).
88. Wang, H., et al., SmLEA2, a gene for late embryogenesis abundant protein isolated from Salvia miltiorrhiza, confers tolerance to drought and salt stress in Escherichia coli and S-miltiorrhiza. Protoplasma, 2017. 254(2): p. 685-696.
89. Wang, G.-Q., et al., HPPR encodes the hydroxyphenylpyruvate reductase required for the biosynthesis of hydrophilic phenolic acids in Salvia miltiorrhiza. Chinese Journal of Natural Medicines, 2017. 15(12): p. 917-927.
90. Wang, F., et al., Reversal of doxorubicin-resistance by Salvia miltiorrhiza ligustrazine in the SHG44/doxorubicin glioma drug-resistant cell line. Oncology Letters, 2017. 14(4): p. 4708-4714.
91. Wang, B., S. Wang, and Z. Wang, Genome-Wide Comprehensive Analysis the Molecular Phylogenetic Evaluation and Tissue-Specific Expression of SABATH Gene Family in Salvia miltiorrhiza. Genes, 2017. 8(12).
92. Tian, J., et al., Anti-thrombolytic effect of Salvia miltiorrhiza Bge extract in rats. Tropical Journal of Pharmaceutical Research, 2017. 16(5): p. 1085-1089.
93. Song, Z., et al., Comparative RNA-Sequence Transcriptome Analysis of Phenolic Acid Metabolism in Salvia miltiorrhiza, a Traditional Chinese Medicine Model Plant. International Journal of Genomics, 2017.
94. Shen, Y., et al., Comparative Analysis of Ultrafine Granular Powder and Decoction Pieces of Salvia miltiorrhiza by UPLC-UV-MSn Combined with Statistical Analysis. Planta Medica, 2017. 83(6): p. 557-564.
95. Park, C.H., et al., Magnesium Lithospermate B from Salvia miltiorrhiza Bunge Ameliorates Aging-Induced Renal Inflammation and Senescence via NADPH Oxidase-Mediated Reactive Oxygen Generation. Phytotherapy Research, 2017. 31(5): p. 721-728.
96. Park, B., et al., Effects of Salvia miltiorrhiza extract with supplemental liquefied calcium on osteoporosis in calcium-deficient ovariectomized mice. Bmc Complementary and Alternative Medicine, 2017. 17.
97. Ozarowski, M., et al., Determination of phenolic compounds and diterpenes in roots of Salvia miltiorrhiza and Salvia przewalskii by two LC-MS tools: Multi-stage and high resolution tandem mass spectrometry with assessment of antioxidant capacity. Phytochemistry Letters, 2017. 20: p. 331-338.
98. Ozarowski, M., et al., Effect of Salvia miltiorrhiza root extract on brain acetylcholinesterase and butyrylcholinesterase activities, their mRNA levels and memory evaluation in rats. Physiology & Behavior, 2017. 173: p. 223-230.
99. Nguyen Huu, T., et al., Bioactive Triterpenes from the Root of Salvia miltiorrhiza Bunge. Phytotherapy Research, 2017. 31(9): p. 1457-1460.
100. Naveed, M., et al., A novel ventricular restraint device (ASD) repetitively deliver Salvia miltiorrhiza to epicardium have good curative effects in heart failure management. Biomedicine & Pharmacotherapy, 2017. 95: p. 701-710.
101. Mu, F., et al., Metabonomic Strategy for the Evaluation of Chinese Medicine Salvia miltiorrhiza and Dalbergia odorifera Interfering with Myocardial Ischemia/Reperfusion Injury in Rats. Rejuvenation Research, 2017. 20(4): p. 263-277.
102. Long, Z., et al., A highly sensitive high performance liquid chromatography-electrochemical detection method for the determination of five phenolic compounds from Salvia miltiorrhiza. Chinese Journal of Chromatography, 2017. 35(8): p. 897-905.
103. Liu, Z.-J., et al., Quality Evaluation of Salvia Miltiorrhiza Bge. Based on Chemical Profile and Bioassay of Anti-platelet Aggregation. Chinese Journal of Analytical Chemistry, 2017. 45(5): p. 693-699.
104. Liu, Z.-j., et al., An activity-calibrated chemical standardization approach for quality evaluation of Salvia miltiorrhiza Bge. Rsc Advances, 2017. 7(9): p. 5331-5339.
105. Liang, W., et al., Quality Evaluation and Chemical Markers Screening of Salvia miltiorrhiza Bge. (Danshen) Based on HPLC Fingerprints and HPLC-MS(n)Coupled with Chemometrics. Molecules, 2017. 22(3).
106. Li, X.-Y., et al., A selective knockout method for discovery of minor active components from plant extracts: Feasibility and challenges as illustrated by an application to Salvia miltiorrhiza. Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences, 2017. 1068: p. 253-260.
107. Li, H. and H. Liu, Investigating the Mechanisms of Action of Depside Salt from Salvia miltiorrhiza Using Bioinformatic Analysis. Evidence-Based Complementary and Alternative Medicine, 2017.
108. Li, B., et al., Targeted mutagenesis in the medicinal plant Salvia miltiorrhiza. Scientific Reports, 2017. 7.
109. Leng, J., et al., Triterpenoids-Enriched Extract from the Aerial Parts of Salvia miltiorrhiza Regulates Macrophage Polarization and Ameliorates Insulin Resistance in High-Fat Fed Mice. Phytotherapy Research, 2017. 31(1): p. 100-107.
110. Kim, J.-M., et al., Salvia miltiorrhiza extract inhibits TPA-induced MMP-9 expression and invasion through the MAPK/AP-1 signaling pathway in human breast cancer MCF-7 cells. Oncology Letters, 2017. 14(3): p. 3594-3600.
111. Kim, D.R., et al., Protective effect of Salvia miltiorrhiza Bunge on 5-fluorouracil-induced oral mucositis. International Journal of Molecular Medicine, 2017. 40(1): p. 39-46.
112. Kim, D.H., et al., Characterization of the inhibitory activity of natural tanshinones from Salvia miltiorrhiza roots on protein tyrosine phosphatase 1B. Chemico-Biological Interactions, 2017. 278: p. 65-73.
113. Jiang, Y., L. Zhang, and H.P.V. Rupasinghe, Antiproliferative effects of extracts from Salvia officinalis L. and Saliva miltiorrhiza Bunge on hepatocellular carcinoma cells. Biomedicine & Pharmacotherapy, 2017. 85: p. 57-67.
114. Jiang, G., et al., Anti-tumor and chemosensitization effects of Cryptotanshinone extracted from Salvia miltiorrhiza Bge. on ovarian cancer cells in vitro. Journal of Ethnopharmacology, 2017. 205: p. 33-40.
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785. Tao, Y.-Y. and C.-H. Liu, Progress of research on mechanism of salvia miltiorrhiza and its chemical ingredients against liver fibrosis. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine, 2004. 2(2): p. 145-8.
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797. Chan, K., et al., Protective effects of Danshensu from the aqueous extract of Salvia miltiorrhiza (Danshen) against homocysteine-induced endothelial dysfunction. Life Sciences, 2004. 75(26): p. 3157-3171.
798. Chae, H.J., et al., Prevention of bone loss in ovariectomized rats: The effect of Salvia miltiorrhiza extracts. Immunopharmacology and Immunotoxicology, 2004. 26(1): p. 135-144.
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800. Yagi, A. and S. Takeo, Anti-inflammatory constituents, aloesin and aloemannan in Aloe species and effects of tanshinon VI in Salvia miltiorrhiza on heart. Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan, 2003. 123(7): p. 517-532.
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803. Wang, X.-f. and M.-q. Zhao, Ligustrazine and Salvia miltiorrhiza injection solution in complementary therapy of pregnancy-induced hypertension: clinical analysis of 60 cases. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2003. 23(9): p. 969-71.
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805. Vacca, G., et al., Reducing effect of Salvia miltiorrhiza extracts on alcohol intake: Influence of vehicle. Phytotherapy Research, 2003. 17(5): p. 537-541.
806. Soung, D.Y., et al., Peroxynitrite scavenging activity of lithospermate B from Salvia miltiorrhiza. Journal of Pharmacy and Pharmacology, 2003. 55(10): p. 1427-1432.
807. Serra, S., et al., Anti-relapse properties of IDN 5082, a standardized extract of Salvia miltiorrhiza, in alcohol-preferring rats. Journal of Ethnopharmacology, 2003. 88(2-3): p. 249-252.
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809. Mosaddik, M.A., In vitro cytotoxicity of Tanshinones isolated from Salvia miltiorrhiza Bunge against P388 lymphocytic leukemia cells. Phytomedicine, 2003. 10(8): p. 682-685.
810. Lo, C.-J., et al., Effect of salvia miltiorrhiza bunge on cerebral infarct in ischemia-reperfusion injured rats. The American journal of Chinese medicine, 2003. 31(2): p. 191-200.
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812. Lee, T.Y., et al., Long-term administration of Salvia miltiorrhiza ameliorates carbon tetrachloride-induced hepatic fibrosis in rats. Journal of Pharmacy and Pharmacology, 2003. 55(11): p. 1561-1568.
813. Lee, T.Y., et al., Protective mechanism of Salvia miltiorrhiza on carbon tetrachloride-induced acute hepatotoxicity in rats. Journal of Pharmacological Sciences, 2003. 91(3): p. 202-210.
814. Lay, I.S., et al., Crude extract of Salvia miltiorrhiza and salvianolic acid B enhance in vitro angiogenesis in murine SVR endothelial cell line. Planta Medica, 2003. 69(1): p. 26-32.
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816. Kang, H.S., et al., Further isolation of antioxidative (+)-1-hydroxypinoresinol-1-O,beta-glucoside from the rhizome of Salvia miltiorrhiza that acts on peroxynitrite, total ROS and 1,1-diphenyl-2-picrylhydrazyl radical. Archives of Pharmacal Research, 2003. 26(1): p. 24-27.
817. Jinping, Q., et al., Effects of the aqueous extract from Salvia miltiorrhiza Bge on the pharmacokinetics of diazepam and on liver microsomal cytochrome P450 enzyme activity in rats. Journal of Pharmacy and Pharmacology, 2003. 55(8): p. 1163-1167.
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820. Huang, Z.Y., et al., Source identification of Salvia Miltiorrhiza BUNGE (Danshen) by lead isotope ratios. Chinese Journal of Analytical Chemistry, 2003. 31(9): p. 1036-1039.
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825. Brunetti, G., et al., IDN 5082, a standardized extract of Salvia miltiorrhiza, delays acquisition of alcohol drinking behavior in rats. Journal of Ethnopharmacology, 2003. 85(1): p. 93-97.
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828. Zhang, X.L., L. Liu, and H.Q. Jiang, Salvia miltiorrhiza monomer IH764-3 induces hepatic stellate cell apoptosis via caspase-3 activation. World Journal of Gastroenterology, 2002. 8(3): p. 515-519.
829. Zhang, H., et al., Contents of four active components in different commercial crude drugs and preparations of Danshen (Salvia miltiorrhiza). Acta Pharmacologica Sinica, 2002. 23(12): p. 1163-1168.
830. Wang, Y.-m., F.-k. Wei, and M. Liu, Effect of Salvia miltiorrhiza on autocrining growth factor by fibroblasts cultured in vitro. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2002. 16(6): p. 408-10.
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833. Takahashi, K., et al., Sodium tanshinone IIA sulfonate derived from Danshen (Salvia miltiorrhiza) attenuates hypertrophy induced by angiotensin II in cultured neonatal rat cardiac cells. Biochemical Pharmacology, 2002. 64(4): p. 745-750.
834. Sugiyama, A., et al., Cardiac effects of Salvia miltiorrhiza/Dalbergia odorifera mixture, an intravenously applicable Chinese medicine widely used for patients with ischemic heart disease in China. Circulation Journal, 2002. 66(2): p. 182-184.
835. Ren, D.C., G.H. Du, and J.T. Zhang, Inhibitory effect of the water-soluble extract of Salvia miltiorrhiza on neutrophil-endothelial adhesion. Japanese Journal of Pharmacology, 2002. 90(3): p. 276-280.
836. Oh, S.H., et al., Salvia miltiorrhiza inhibits biliary obstruction-induced hepatocyte apoptosis by cytoplasmic sequestration of p53. Toxicology and Applied Pharmacology, 2002. 182(1): p. 27-33.
837. Lu, H.-q., Verification of "lidocain in combination with injectio Salvia miltiorrhiza composita in treating vertigo" published by "Chinese Journal of New Drugs and Clinical Remedies". Zhongguo Xinyao yu Linchuang Zazhi, 2002. 21(5): p. 312-313.
838. Li, J.-c., Z.-r. Yang, and K. Zhang, The intervention effects of Angelica sinensis, Salvia miltiorrhiza and ligustrazine on peritoneal macrophages during peritoneal dialysis. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2002. 22(3): p. 190-2.
839. Li, H.B., et al., Preparative isolation and purification of salvianolic acid B from the Chinese medicinal plant Salvia miltiorrhiza by high-speed counter-current chromatography. Journal of Chromatography A, 2002. 943(2): p. 235-239.
840. Ko, J.S., et al., Inhibitory activity of diacylglycerol acyltransferase by tanshinones from the root of Salvia miltiorrhiza. Archives of Pharmacal Research, 2002. 25(4): p. 446-448.
841. Kim, S.Y., et al., Effects of tanshinone I isolated from Salvia miltiorrhiza bunge on arachidonic acid metabolism and in vivo inflammatory responses. Phytotherapy Research, 2002. 16(7): p. 616-620.
842. Jiang, L., et al., Protective effect of chitosan plus Polygonum multiflorum, Salvia miltiorrhiza, and Achyronthes bidentata on rats of experimental fatty liver. Zhongguo Xinyao yu Linchuang Zazhi, 2002. 21(8): p. 462-466.
843. JeongSukKo, et al., Inhibitory Activity of Diacylglycerol Acyltransferase by Tanshinones from the Root of Salvia miltiorrhiza. Archives of Pharmacal Research, 2002. 25(4): p. 446-448.
844. Hong, X.-r., A.-q. Wu, and Z.-d. You, Effect of Salvia miltiorrhiza on neuropeptide Y1-36 and calcitonin gene-related peptide in neonatal rats with hypoxia-ischemic brain injury. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2002. 22(8): p. 607-9.
845. Han, S., Z. Zheng, and D. Ren, Effect of Salvia miltiorrhiza on left ventricular hypertrophy and cardiac aldosterone in spontaneously hypertensive rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2002. 22(4): p. 302-4.
846. Guo, B.-l., Y.-x. Feng, and Y.-j. Zhao, Review of germplasm resources studies on Salvia miltiorrhiza. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2002. 27(7): p. 492-5.
847. Chen, Y., et al., Amelioration of carbon tetrachloride-induced hepatic fibrosis in rats by treatment with salvia miltiorrhiza and taurine. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2002. 10(2): p. 148-9.
848. Chen, Y., et al., Antiproliferative effect of IH764-3 derived from Salvia miltiorrhiza in cultured rat hepatic stellate cells. Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2002. 10(3): p. 223-223.
849. Abd-Elazem, I.S., et al., Isolation of two highly potent and non-toxic inhibitors of human immunodeficiency virus type 1 (HIV-1) integrase from Salvia miltiorrhiza. Antiviral Research, 2002. 55(1): p. 91-106.
850. Zhu, D.-n., et al., Determination of effective constituents in autotetraploid elite line of Salvia miltiorrhiza Bunge and primary pharmacological experiments. Journal of Plant Resources and Environment, 2001. 10(2): p. 7-10.
851. Zhang, R., D. Wang, and R. Zhang, Study on extraction process of aqueous part of radix Salvia miltiorrhiza. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2001. 24(11): p. 818-9.
852. Wang, A.M., et al., Effect of injectio Salvia Miltiorrhiza on gentamicin ototoxicity-induced activity of nitric oxide synthase in cochlear stria vascularis of guinea pig. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2001. 17(1): p. 89-92.
853. Peng, B., et al., The effect of salvia miltiorrhiza and shengmai on inflammatory mediator and renal function of post-operative patients with obstructive jaundice. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 2001. 32(4): p. 587-9.
854. Peng, B., et al., The effect of Salvia miltiorrhiza and shengmai on inflammatory mediator and renal function of post-operative patients with obstructive jaundice. Journal of West China University of Medical Sciences, 2001. 32(4): p. 587-589.
855. Pan, X.J., G.G. Niu, and H.Z. Liu, Microwave-assisted extraction of tanshinones from Salvia miltiorrhiza bunge with analysis by high-performance liquid chromatography. Journal of Chromatography A, 2001. 922(1-2): p. 371-375.
856. Ouyang, X., et al., Protective effect of Salvia miltiorrhiza on angiotensin II-induced hypertrophic responses in neonatal rat cardiac cells. Japanese Journal of Pharmacology, 2001. 87(4): p. 289-296.
857. Nan, J.X., et al., Anti-fibrotic effects of a hot-water extract from Salvia miltiorrhiza roots an liver fibrosis induced by biliary obstruction in rats. Journal of Pharmacy and Pharmacology, 2001. 53(2): p. 197-204.
858. Luo, X.J., et al., Determination of Danshensu, a major active compound of Radix Salvia miltiorrhiza in dog plasma by HPLC with fluorescence detection. Biomedical Chromatography, 2001. 15(8): p. 493-496.
859. Liu, J., et al., Protection of Salvia Miltiorrhiza against aflatoxin-B-1-induced hepatocarcinogenesis in Fischer 344 rats - Dual mechanisms involved. Life Sciences, 2001. 69(3): p. 309-326.
860. Liu, J., H.M. Shen, and C.N. Ong, Role of intracellular thiol depletion, mitochondrial dysfunction and reactive oxygen species in Salvia Miltiorrhiza-induced apoptosis in human hepatoma HepG(2) Cells. Life Sciences, 2001. 69(16): p. 1833-1850.
861. Lin, H.C., H.Y. Ding, and W.L. Chang, Two new fatty diterpenoids from Salvia miltiorrhiza. Journal of Natural Products, 2001. 64(5): p. 648-650.
862. Li, H.B. and F. Chen, Preparative isolation and purification of six diterpenoids from the Chinese medicinal plant Salvia miltiorrhiza by high-speed counter-current chromatography. Journal of Chromatography A, 2001. 925(1-2): p. 109-114.
863. Hung, H.H., et al., A salvianolic acid B-rich fraction of Salvia miltiorrhiza induces neointimal cell apoptosis in rabbit angioplasty model. Histology and Histopathology, 2001. 16(1): p. 175-183.
864. Huang, Y.T., et al., Hemodynamic effects of Salvia miltiorrhiza on cirrhotic rats. Canadian Journal of Physiology and Pharmacology, 2001. 79(7): p. 566-572.
865. Choi, J.S., et al., A new cyclic phenyllactamide from Salvia miltiorrhiza. Fitoterapia, 2001. 72(1): p. 30-34.
866. Chen, Y.L., et al., Salvia miltiorrhiza inhibits intimal monocyte chemotactic protein-1 balloon injury in cholesterol-fed hyperplasia and expression after rabbits. Journal of Cellular Biochemistry, 2001. 83(3): p. 484-493.
867. Chen, G., et al., Effect of Salvia miltiorrhiza Bunge injectio on anticardiolipin antibody production induced by beta 2 glycoprotein. Acta Pharmacologica Sinica, 2001. 22(12): p. 1125-1129.
868. Chen, G., et al., Effect of salvia miltiorrhiza bunge injectio on aCL induced by beta2-GPI. Xi'an Yike Daxue Xuebao, 2001. 22(5): p. 429-431.
869. Chen, B., et al., SFE-CGC determination of tanshinone in Salvia miltiorrhiza Bunge. Yaoxue Xuebao, 2001. 36(1): p. 55-57.
870. Chan, T.Y.K., Interaction between warfarin and danshen (Salvia miltiorrhiza). Annals of Pharmacotherapy, 2001. 35(4): p. 501-504.
871. Zhang, Y.-Y. and R.-X. Chen, Astragalus membranaceus and Salvia miltiorrhiza injection in treating acute cerebral infarction. Zhongguo Xinyao yu Linchuang Zazhi, 2000. 19(1): p. 30-32.
872. Tian, G.L., et al., Separation of tanshinones from Salvia miltiorrhiza Bunge by high-speed counter-current chromatography using stepwise elution. Journal of Chromatography A, 2000. 904(1): p. 107-111.
873. Su, L., et al., Comparisons different doses of Astragali membranaceus and Salvia miltiorrhiza in rats proteinuria. Zhongguo Xinyao yu Linchuang Zazhi, 2000. 19(3): p. 205-208.
874. Song, J.Y., et al., Effect of Armillaria mellea elicitor on accumulation of tanshinones in crown gall cultures of Salvia miltiorrhiza. Acta Botanica Sinica, 2000. 42(3): p. 316-320.
875. Shi, X., Z. Xia, and J. Fang, Effects of Salvia miltiorrhiza compound injection on serum endothelin, prostaglandin I2/thromboxane A2 ratio alteration following myocardial ischemia-reperfusion in patients undergoing intracardiac surgery. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 2000. 20(12): p. 896-8.
876. Liu, J., H.M. Shen, and C.N. Ong, Salvia miltiorrhiza inhibits cell growth and induces apoptosis in human hepatoma HepG(2) cells. Cancer Letters, 2000. 153(1-2): p. 85-93.
877. Lin, H.C. and W.L. Chang, Diterpenoids from Salvia miltiorrhiza. Phytochemistry, 2000. 53(8): p. 951-953.
878. Li, F., et al., Nicergoline and Salvia miltiorrhiza in treating acute cerebral infarction. Zhongguo Xinyao yu Linchuang Zazhi, 2000. 19(4): p. 261-263.
879. Kang, B.Y., et al., Inhibition of interleukin-12 and interferon-gamma production in immune cells by tanshinones from Salvia miltiorrhiza. Immunopharmacology, 2000. 49(3): p. 355-361.
880. Ji, X.Y., B.K.H. Tan, and Y.Z. Zhu, Salvia miltiorrhiza and ischemic diseases. Acta Pharmacologica Sinica, 2000. 21(12): p. 1089-1094.
881. Huang, L., D. Liu, and Z. Hu, Effects of phytohormones on growth and content of depsides in Salvia miltiorrhiza suspension cells. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2000. 23(1): p. 1-4.
882. Chen, J.-S., L.-K. Zhao, and W.-D. Su, Panax notoginseng saporins injection vs compound Salvia miltiorrhiza injection in treatment of coronary heart disease with angina pectoris. Zhongguo Xinyao yu Linchuang Zazhi, 2000. 19(6): p. 458-460.
883. An, P. and Q. Wang, Acanthopanax senticosus vs Salvia miltiorrhiza injection in treating unstable angina. Zhongguo Xinyao yu Linchuang Zazhi, 2000. 19(5): p. 415-416.
884. Zhou, S., W. Shao, and C. Duan, Observation of preventing and treating effect of Salvia miltiorrhiza composita on patients with ischemic coronary heart disease undergoing non-heart surgery. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1999. 19(2): p. 75-6.
885. Yoon, Y., et al., Tanshinone IIA isolated from Salvia miltiorrhiza BUNGE induced apoptosis in HL60 human premyelocytic leukemia cell line. Journal of Ethnopharmacology, 1999. 68(1-3): p. 121-127.
886. Sung, H.J., et al., Tanshinone IIA, an ingredient of Salvia miltiorrhiza BUNGE, induces apoptosis in human leukemia cell lines through the activation of caspase-3. Experimental and Molecular Medicine, 1999. 31(4): p. 174-178.
887. Ryu, S.Y., M.H. Oak, and K.M. Kim, Inhibition of mast cell degranulation by tanshinones from the roots of Salvia miltiorrhiza. Planta Medica, 1999. 65(7): p. 654-655.
888. Liu, Q. and Z. Lu, Effect of Salvia Miltiorrhiza on coronary collateral circulation in dogs with experimental acute myocardial infarction. Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 1999. 19(1): p. 40-69.
889. Liu, J., et al., Effect of Salvia miltiorrhiza on aflatoxin B-1-induced oxidative stress in cultured rat hepatocytes. Free Radical Research, 1999. 31(6): p. 559-568.
890. Liu, B., J. Lu, and Z. Ma, Comparison of protocatechuic aldehyde in different processed products of Salvia miltiorrhiza. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 1999. 22(11): p. 570-1.
891. Lee, D.S., et al., Antibacterial activities of cryptotanshinone and dihydrotanshinone I from a medicinal herb, Salvia miltiorrhiza Bunge. Bioscience Biotechnology and Biochemistry, 1999. 63(12): p. 2236-2239.
892. Lee, D.S., et al., Inhibition of DNA topoisomerase I by dihydrotanshinone I, components of a medicinal herb Salvia miltiorrhiza bunge. Bioscience Biotechnology and Biochemistry, 1999. 63(8): p. 1370-1373.
893. Hou, J., L. Dai, and M. Huang, The therapeutic effect of ligustrazin and salvia miltiorrhiza on the gene expression of alpha1 (I) and alpha1 (III) procollagen in rat pulmonary fibrosis. Zhonghua Jiehe He Huxi Zazhi, 1999. 22(1): p. 43-45.
894. Colombo, G., et al., Salvia miltiorrhiza extract inhibits alcohol absorption, preference, and discrimination in sP rats. Alcohol, 1999. 18(1): p. 65-70.
895. Chen, H. and F. Chen, Kinetics of cell growth and secondary metabolism of a high-tanshinone-producing line of the Ti transformed Salvia miltiorrhiza cells in suspension culture. Biotechnology Letters, 1999. 21(8): p. 701-705.
896. Buchwald, W., Preliminary studies on cultivation of Salvia miltiorrhiza Bunge in Poland and evaluation of its raw material. Acta Agrobotanica, 1999. 52(1-2): p. 153-160.
897. Zhang, T., L. Du, and P. Cui, Experimental study of hirudo and Salvia miltiorrhiza on smooth muscle cell hyperplasia after balloon angioplasty. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1998. 18(3): p. 159-61.
898. Yuan, J.P., H. Chen, and F. Chen, Simultaneous determination of rosmarinic acid, lithospermic acid B, and related phenolics in Salvia miltiorrhiza by HPLC. Journal of Agricultural and Food Chemistry, 1998. 46(7): p. 2651-2654.
899. Wu, Y.J., et al., Increase of vitamin E content in LDL and reduction of atherosclerosis in cholesterol-fed rabbits by a water-soluble antioxidant-rich fraction of Salvia miltiorrhiza. Arteriosclerosis Thrombosis and Vascular Biology, 1998. 18(3): p. 481-486.
900. Wasser, S., et al., Salvia miltiorrhiza reduces experimentally-induced hepatic fibrosis in rats. Journal of Hepatology, 1998. 29(5): p. 760-771.
901. Wang, K., Q. Luo, and H. Cheng, Study on production of allochtonic formations in callus cells of Salvia miltiorrhiza Bge. Zhongguo Zhongyao Zazhi, 1998. 23(10): p. 592-638.
902. Shu, Y., W. Zhu, and Q. Hu, Studies on chemical constituents of tissue cultures of Salvia miltiorrhiza Bunge. Zhongguo Zhongyao Zazhi, 1998. 23(3): p. 166-192.
903. Shang, Q., D. Zhang, and W. Guan, The influence of salvia miltiorrhiza and tetramethyl pyrazine on DNA content of cicatricial fibroblasts and its cellular cycle. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 1998. 12(6): p. 325-8.
904. Shang, Q., D. Zhang, and W. Guan, The inhibitory effect in vitro of salvia miltiorrhiza and tetramethyl pyrazine on the growth of fibroblasts. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 1998. 12(6): p. 321-4.
905. Li, X., Y. Zhuang, and C. Chang, Effect of Salvia Miltiorrhiza injection on umbilical artery hemodynamics during fetal distress in ewe. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1998. 18(9): p. 543-5.
906. Li, W., et al., Effect of Salvia miltiorrhiza on the non-enzymatic binding of glucose with protein in vitro. Acta Academiae Medicinae Shanghai, 1998. 25(2): p. 133-135.
907. Li, M., Q. Wang, and C. Yang, Effects of Salvia miltiorrhiza Bunge on the proliferation and collagen synthesis in systemic scleroderma skin fibroblasts. Zhonghua Pifuke Zazhi, 1998. 31(1): p. 22-24.
908. Lee, D.S. and S.D. Hong, Inhibition of DNA topoisomerase I by cryptotanshinone from Salvia miltiorrhiza. Journal of Microbiology and Biotechnology, 1998. 8(1): p. 89-91.
909. Dean, J.R., B. Liu, and R. Price, Extraction of Tanshinone IIA from Salvia miltiorrhiza bunge using supercritical fluid extraction and a new extraction technique, phytosol solvent extraction. Journal of Chromatography A, 1998. 799(1-2): p. 343-348.
910. Chen, X., et al., Effect of d-limonene, Salvia miltiorrhiza and turmeric derivatives on membrane association of Ras gene product and gap junction intercellular communication. Yaoxue Xuebao, 1998. 33(11): p. 821-827.
911. Zhang Yinlin, S.J., J. Qi, and G. Lu, The plant regeneration of Salvia miltiorrhiza Bge. transformed by Agrobacterium. Zhongguo Zhongyao Zazhi, 1997. 22(5): p. 274-318.
912. Zhang, Y., et al., The plant regeneration of Salvia miltiorrhiza Bge. transformed by Agrobacterium. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1997. 22(5): p. 274-318.
913. Wang, Z.W., S.Z. Gao, and B.C. Cheng, Observation of therapeutic effect by combined administration of Salvia miltiorrhiza, ligustrazine and Panax notoginseng on late hemorrhagic shock of rabbits. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1997. 17(5): p. 292-4.
914. Tezuka, Y., et al., Aldose reductase inhibitory constituents of the root of Salvia miltiorhiza BUNGE. Chemical & Pharmaceutical Bulletin, 1997. 45(8): p. 1306-1311.
915. Ryu, S.Y., et al., Two novel abietene diterpenes from Salvia miltiorrhiza. Planta Medica, 1997. 63(1): p. 44-46.
916. Ryu, S.Y., C.O. Lee, and S.U. Choi, In vitro cytotoxicity of tanshinones from Salvia miltiorrhiza. Planta Medica, 1997. 63(4): p. 339-342.
917. Kasimu, R., et al., Danshenols A and B, new aldose reductase inhibitors from the root of Salvia miltiorhiza BUNGE. Chemical & Pharmaceutical Bulletin, 1997. 45(3): p. 564-566.
918. Kang, H.S., et al., Antioxidant effect of Salvia miltiorrhiza. Archives of Pharmacal Research, 1997. 20(5): p. 496-500.
919. Jiang, Z.S., S.L. Zhang, and X.J. Cai, Effect of salvia miltiorrhiza composita on superoxide dismutase and malonyldialdehyde in treating patients with non-insulin dependent diabetes mellitus (NIDDM). Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1997. 17(1): p. 32-4.
920. Chen, X., et al., A comparative study on the chemical components of Salvia miltiorrhiza Bge. collected from Zhongjiang of Sichuan and from other habitats. Zhongguo Zhongyao Zazhi, 1997. 22(9): p. 522-574.
921. Chen, H., et al., Tanshinone production in Ti-transformed Salvia miltiorrhiza cell suspension cultures. Journal of Biotechnology, 1997. 58(3): p. 147-156.
922. Zhou, X.M., Z.Y. Lu, and D.W. Wang, Experimental study of Salvia miltiorrhiza on prevention of restenosis after angioplasty. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1996. 16(8): p. 480-2.
923. Zhao, B.L., et al., Scavenging effects of salvia miltiorrhiza on free radicals and its protection for myocardial mitochondrial membranes from ischemia-reperfusion injury. Biochemistry and Molecular Biology International, 1996. 38(6): p. 1171-1182.
924. Xing, Z.Q., X.C. Zeng, and C.T. Yi, Effect of Salvia miltiorrhiza on serum lipid peroxide, superoxide dismutase of the patients with coronary heart disease. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1996. 16(5): p. 287-8.
925. Wang Shu, S.Y. and Y. Jia, The technique for extracting liposoluble components of Salvia miltiorrhiza. Journal of West China University of Medical Sciences, 1996. 27(2): p. 203-205.
926. Wang, J., Preparation of Salvia miltiorrhiza powder for injection. Zhongguo Yiyao Gongye Zazhi, 1996. 27(1): p. 16-19.
927. Lin, H.C., et al., Tanshinketolactone, a new tanshinone from Salvia miltiorrhiza. Journal of the Chinese Chemical Society, 1996. 43(2): p. 199-201.
928. Kuo, Y.H. and C.H. Wu, Synthesis of 5-(3-hydroxypropyl)-7-methoxy-2-(3'-methoxy-4'-hydroxyphenyl)-3-benzo b furancarbaldehyde, a novel adenosine A(1) receptor ligand from the root of Salvia miltiorrhiza. Journal of Natural Products, 1996. 59(6): p. 625-628.
929. Hu, L., T. Yu, and Z. Jia, Experimental study of the protective effects of astragalus and salvia miltiorrhiza bunge on glycerol induced acute renal failure in rabbits. Zhonghua wai ke za zhi [Chinese journal of surgery], 1996. 34(5): p. 311-4.
930. Gao, S.L., et al., Autotetraploid plants form colchicine-treated bud culture of Saliva miltiorrhiza Bge. Plant Cell Tissue and Organ Culture, 1996. 47(1): p. 73-77.
931. Zhang, Y., et al., Crown gall culture and production of tanshinone in Salvia miltiorrhiza. Chinese journal of biotechnology, 1995. 11(2): p. 137-41.
932. Wang Ling, H.X., et al., The effects of Salvia miltiorrhiza and polysaccharide sulphate on the adhesion of erythrocytes of patients with cerebral thrombosis to cultured endothelial cells. Journal of West China University of Medical Sciences, 1995. 26(4): p. 381-385.
933. Wang, L., et al., The effects of Salvia miltiorrhiza and polysaccharide sulphate on the adhesion of erythrocytes of the patients with cerebral thrombosis to cultured endothelial cells. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1995. 26(4): p. 381-5.
934. Tam, L.S., et al., WARFARIN INTERACTIONS WITH CHINESE TRADITIONAL MEDICINES - DANSHEN AND METHYL SALICYLATE MEDICATED OIL. Australian and New Zealand Journal of Medicine, 1995. 25(3): p. 258-258.
935. Liu, J.K., J. Zapp, and H. Becker, COMPARATIVE PHYTOCHEMICAL INVESTIGATION OF SALVIA-MILTIORRHIZA AND SALVIA-TRILOBA. Planta Medica, 1995. 61(5): p. 453-455.
936. Lin, H.-C., W.L. Chang, and C.-F. Chen, Phytochemical and pharmacological study on Salvia miltiorrhia (VI)-cytotoxic activity of Tanshinones. Chinese Pharmaceutical Journal, 1995. 47(1): p. 77-80.
937. Ding, Y., et al., Effects of salvia miltiorrhiza bunge (SMB) on MC3T3-E1 cells. The Journal of Osaka University Dental School, 1995. 35: p. 21-7.
938. Deng, C., et al., Effect of radix salvia miltiorrhiza on levels on LPO SOD and GSH-Px in rats with acute gastric mucosal damage. Acta Academiae Medicinae Hubei, 1995. 16(2): p. 121-124.
939. Chen, G.-L. and S.-M. Zhang, Spectrophotometric determination of glucose in injection of Salvia miltiorrhiza. Zhongguo Yiyao Gongye Zazhi, 1995. 26(2): p. 68-70.
940. Chan, K., et al., THE EFFECTS OF DANSHEN (SALVIA-MILTIORRHIZA) ON WARFARIN PHARMACODYNAMICS AND PHARMACOKINETICS OF WARFARIN ENANTIOMERS IN RATS. Journal of Pharmacy and Pharmacology, 1995. 47(5): p. 402-406.
941. Battistini, M., A. Griffini, and F. Peterlongo, Identification of tanshinones from Salvia miltiorrhiza roots by liquid chromatography-thermospray mass spectrometry. Fitoterapia, 1995. 66(3): p. 265-272.
942. Zhang, P.T. and Z.R. Chen, Effect of Salvia miltiorrhiza on lipid peroxidation antioxidant enzymes activity in patients with chronic cor pulmonale. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1994. 14(8): p. 474-7.
943. Wang, R.Q., J.Z. Chen, and G.Y. Ren, Intraperitoneal perfusion of compound injection of salvia miltiorrhiza with dachengqi decoction in treating adhesive intestinal obstruction. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1994. 14(10): p. 595-7.
944. Peng, A., Quantitative analysis of amino acids and inorganic elements in Salvia miltiorrhiza bge. Hunan Yike Daxue Xuebao, 1994. 19(6): p. 571-572.
945. Morimoto, S., Y. Goto, and Y. Shoyama, PRODUCTION OF LITHOSPERMIC ACID-B AND ROSMARINIC ACID IN CALLUS-TISSUE AND REGENERATED PLANTLETS OF SALVIA-MILTIORRHIZA. Journal of Natural Products, 1994. 57(6): p. 817-823.
946. Ma, D., Application of Salvia miltiorrhiza in surgical clinical practice. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1994. 14(4): p. 254-6.
947. Huang, X., T. Xia, and P. Ren, Influence of combined Salvia miltiorrhiza and Ligusticum wallichii on pharmacokinetics of tetramethylpyrazine in rats. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1994. 14(5): p. 288-91, 261-2.
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949. Bai, Y.R. and S.Z. Wang, Hemodynamic study on nitroglycerin compared with Salvia miltiorrhiza. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1994. 14(1): p. 24-4.
950. Yang, Y., et al., The effects of salvia miltiorrhiza, polysaccharide sulphate, dextran 40 and mannitol on the viscoelasticity properties of red blood cell suspension. Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao, 1993. 24(2): p. 143-6.
951. Xiong, L.L., Therapeutic effect of combined therapy of Salvia miltiorrhizae and Polyporus umbellatus polysaccharide in the treatment of chronic hepatitis B. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1993. 13(9): p. 533-5, 516-7.
952. Tao, Y.Y., Effects of Salvia miltiorrhizae compositae on phosphoinositides metabolism in acute myocardial ischemia. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1993. 13(6): p. 354-326.
953. Ling, M., et al., THE WATER-SOLUBLE COMPONENT OF SALVIA-MILTIORRHIZA BGE CAN PROMOTE MACROPHAGE SYNTHESIS OF C4 IN-VIVO AND IN-VITRO. Experimental and Clinical Immunogenetics, 1993. 10(1): p. 45-49.
954. Lin, H.-C. and W.-L. Chang, A new Tanshinone from Salvia miltiorrhiza. Chinese Pharmaceutical Journal, 1993. 45(6): p. 615-618.
955. Lin, H.-C. and W.-L. Chang, Phytochemical and pharmacological study on Salvia miltiorrhiza: (IV). Cytotoxic activity of tanshinones. Chinese Pharmaceutical Journal, 1993. 45(1): p. 85-87.
956. Lin, H.-C. and W.-L. Chang, Phytochemical and pharmacological study on Salvia miltiorrhiza: (III). Isolation of new tanshinones. Chinese Pharmaceutical Journal, 1993. 45(1): p. 21-27.
957. Li, J., L.Y. He, and W.Z. Song, Separation and quantitative determination of seven aqueous depsides in Salvia miltiorrhiza by HPTLC scanning. Yao xue xue bao = Acta pharmaceutica Sinica, 1993. 28(7): p. 543-7.
958. Hu, Z.B. and A.W. Alfermann, DITERPENOID PRODUCTION IN HAIRY ROOT CULTURES OF SALVIA-MILTIORRHIZA. Phytochemistry, 1993. 32(3): p. 699-703.
959. Fung, K.P., et al., Demonstration of the myocardial salvage effect of lithospermic acid B isolated from the aqueous extract of Salvia miltiorrhiza. Life Sciences, 1993. 52(22): p. PL239-PL244.
960. Yu, Z.P., et al., Effects of Salvia miltiorrhiza Bunge on isolated perfused liver and portal vein of rats. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1992. 17(12): p. 749-764.
961. Weng, X.C. and M.H. Gordon, ANTIOXIDANT ACTIVITY OF QUINONES EXTRACTED FROM TANSHEN (SALVIA-MILTIORRHIZA BUNGE). Journal of Agricultural and Food Chemistry, 1992. 40(8): p. 1331-1336.
962. Qin, J.Z. and X.C. Wang, Effect of radix Salviae miltiorrhizae on calcium, zinc, copper content in serum, callus and bony tissue in early stage of healing process in rat closed tibial fracture. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1992. 12(6): p. 354-6, 325-6.
963. Okamura, N., et al., AN APPLICATION OF HPLC FOR IDENTIFICATION OF ABIETANE-TYPE PIGMENTS FROM SALVIA-MILTIORRHIZA AND THEIR EFFECTS ON POSTHYPOXIC CARDIAC CONTRACTILE-FORCE IN RATS. Planta Medica, 1992. 58(6): p. 571-572.
964. Lo, A.C.T., et al., THE EFFECTS OF DANSHEN (SALVIA-MILTIORRHIZA) ON PHARMACO-KINETICS AND PHARMACODYNAMICS OF WARFARIN IN RATS. European Journal of Drug Metabolism and Pharmacokinetics, 1992. 17(4): p. 257-262.
965. Liu, G.T., et al., PROTECTIVE ACTION OF SEVEN PHENOLIC COMPOUND ISOLATED FROM SALVIA-MILTIORRHIZA AGAINST PEROXIDATIVE DAMAGE TO BIOMEMBRANES. Zhongguo Yaolixue Yu Dulixue Zazhi, 1992. 6(1): p. 77-77.
966. Huang, Y.S. and J.T. Zhang, ANTIOXIDATIVE EFFECT OF THREE WATER-SOLUBLE COMPONENTS ISOLATED FROM SALVIA-MILTIORRHIZA IN-VITRO. Yaoxue Xuebao, 1992. 27(2): p. 96-100.
967. Huang, M.-H. and X.-Z. Lu, Total synthesis of active diterpenoid quinones in Salvia miltiorrhiza Bunge. Chinese Journal of Pharmaceuticals, 1992. 23(6): p. 279-283.
968. Hu, Z.B. and A.W. Alfermann, Diterpenoid production in hairy root cultures of Salvia miltiorrhiza. Planta Medica, 1992. 58(7 SUPPL. 1): p. A621-A621.
969. Gordon, M.H. and X.C. Weng, ANTIOXIDANT PROPERTIES OF EXTRACTS FROM TANSHEN (SALVIA-MILTIORRHIZA-BUNGE). Food Chemistry, 1992. 44(2): p. 119-122.
970. Cheng, Y.Y., S.M. Fong, and P.M. Hon, Effect of Salvia miltiorrhiza on the cardial ischemia in rats induced by ligation. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1992. 12(7): p. 424-390.
971. Bombardelli, E., L. Verotta, and D. Barone, Enhancement of adenylate cyclase activity by Salvia miltiorrhiza and tanshinone IIA. Planta Medica, 1992. 58(7 SUPPL. 1): p. A664-A665.
972. Ai, C.B. and L.N. Li, SALVIANOLIC ACID-D AND ACID-E - 2 NEW DEPSIDES FROM SALVIA-MILTIORRHIZA. Planta Medica, 1992. 58(2): p. 197-199.
973. Zhang, F.C. and L.J. Zheng, Effects of different administration of Salvia miltiorrhiza and heparin on antithrombin IIIAg, antithrombin III: A and alpha 2-macroglobulin in patients with cor pulmonale. Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1991. 11(10): p. 589-579.
974. Yang, Z., et al., NATURALLY-OCCURRING BENZOFURAN - ISOLATION, STRUCTURE ELUCIDATION AND TOTAL SYNTHESIS OF 5-(3-HYDROXYPROPYL)-7-METHOXY-2-(3'-METHOXY-4'-HYDROXYPHENYL)-3-BENZO B FURANCARBALDEHYDE, A NOVEL ADENOSINE-A1-RECEPTOR LIGAND ISOLATED FROM SALVIA-MILITORRHIZA BUNGE (DANSHEN). Tetrahedron Letters, 1991. 32(18): p. 2061-2064.
975. Yagi, A., et al., EFFECT OF ABIETANE-TYPE PIGMENTS FROM SALVIA-MILTIORRHIZA ON POSTHYPOXIC RECOVERY OF CARDIAC CONTRACTILE-FORCE IN RATS. Planta Medica, 1991. 57(3): p. 288-289.
976. Wang, J.Z., M.E. Chen, and Y.Q. Xu, Effect of Salvia miltiorrhiza co. on angiotensin II and atrial natriuretic polypeptide in rabbits. Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1991. 11(7): p. 420-390.
977. Shimomura, K., et al., TANSHINONE PRODUCTION IN ADVENTITIOUS ROOTS AND REGENERATES OF SALVIA-MILTIORRHIZA. Journal of Natural Products, 1991. 54(6): p. 1583-1587.
978. Qi, X.G., Protective mechanism of Salvia miltiorrhiza and Paeonia lactiflora for experimental liver damage. Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1991. 11(2): p. 102-69.
979. Lin, H.C., W.L. Chang, and G.L. Chen, PHYTOCHEMICAL AND PHARMACOLOGICAL STUDY ON SALVIA-MILTIORRHIZA II. CYTOTOXIC ACTIVITY OF TANSHINONES. Chinese Pharmaceutical Journal (Taipei), 1991. 43(6): p. 501-504.
980. Lin, H.C. and W.L. Chang, PHYTOCHEMICAL AND PHARMACOLOGICAL STUDY ON SALVIA-MILTIORRHIZA I. ISOLATION OF NEW TANSHINONES. Chinese Pharmaceutical Journal (Taipei), 1991. 43(1): p. 11-18.
981. Li, Z.T., B.J. Yang, and G.E. Ma, CHEMICAL STUDIES OF SALVIA-MILTIORRHIZA-F-ALBA. Yaoxue Xuebao, 1991. 26(3): p. 209-213.
982. Li, Z.T., B.J. Yang, and G.E. Ma, Chemical studies of Salvia miltiorrhiza f. alba. Yao xue xue bao = Acta pharmaceutica Sinica, 1991. 26(3): p. 209-13.
983. Lee, C.M., et al., MILTIRONE, A CENTRAL BENZODIAZEPINE RECEPTOR PARTIAL AGONIST FROM A CHINESE MEDICINAL HERB SALVIA-MILTIORRHIZA. Neuroscience Letters, 1991. 127(2): p. 237-241.
984. Ikeshiro, Y., et al., DITERPENOIDS FROM SALVIA-MILTIORRHIZA. Phytochemistry, 1991. 30(8): p. 2791-2792.
985. Haro, G., et al., STRUCTURES OF DITERPENOID TROPOLONES, SALVIOLONE AND MILTIPOLONE, FROM THE ROOT OF SALVIA-MILTIORRHIZA BUNGE. Bulletin of the Chemical Society of Japan, 1991. 64(11): p. 3422-3426.
986. Cheng, Y.Y., et al., Prevention and treatment of isoproterenol induced ventricular fibrillation in rats by aqueous extract of Salvia miltiorrhiza. Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1991. 11(9): p. 543-518.
987. Chang, H.M., et al., COMPOUNDS FROM DANSHEN .4. STRUCTURE ACTIVITY RELATIONSHIP OF MILTIRONE, AN ACTIVE CENTRAL BENZODIAZEPINE RECEPTOR LIGAND ISOLATED FROM SALVIA-MILTIORRHIZA BUNGE (DANSHEN). Journal of Medicinal Chemistry, 1991. 34(5): p. 1675-1692.
988. Xu, H.T., S.L. Chen, and L.S. Li, Effect of Salvia miltiorrhiza on the left ventricular diastolic function in coronary artery stenosis. Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1990. 10(12): p. 737-710.
989. Lee, J. and J.K. Snyder, ULTRASOUND-PROMOTED CYCLOADDITIONS IN THE SYNTHESIS OF SALVIA-MILTIORRHIZA ABIETANOID ORTHO-QUINONES. Journal of Organic Chemistry, 1990. 55(17): p. 4995-5008.
990. He, Y., et al., SYNTHESIS OF DIAZEPAM RELATED ANALOGS OF MILTIRONE, AN ACTIVE CENTRAL BENZODIAZEPINE RECEPTOR LIGAND ISOLATED FROM SALVIA-MILTIORRHIZA BUNGE (DANSHEN). Journal of the Chemical Society-Perkin Transactions 1, 1990(12): p. 3359-3361.
991. Haro, G. and H. Kakisawa, MILTIPOLONE, A NEW DITERPENOID TROPOLONE POSSESSING CYTOTOXIC ACTIVITIES FROM SALVIA-MILTIORRHIZA BUNGE. Chemistry Letters, 1990(9): p. 1599-1602.
992. Cheng, Y.Y., S.M. Fong, and H.M. Chang, Protective action of Salvia miltiorrhiza aqueous extract on chemically induced acute myocardial ischemia in rats. Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1990. 10(10): p. 609-582.
993. Asari, F., et al., CRYPTOACETALIDE AND EPICRYPTOACETALIDE, NOVEL SPIROLACTONE DITERPENOIDS FROM SALVIA-MILTIORRHIZA. Chemistry Letters, 1990(10): p. 1885-1888.
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