Thursday, March 1, 2012

Picrorhiza kurroa - Kutki Articles, Patents



Picrorhiza kurroa Royle ex Benth
Fam. Scrophulariaceae
Sanskrit : Katuka katurohini
Assamese : Katki, Kutki
English : Hellebore
Gujrati : Kadu, Katu
Hindi : Kutki
Kannada : Katuka rohini, katuka rohini
Malayalam : Kaduk rohini, Katuka rohini
Marathi : Kutki, Kalikutki
Oriya : Katuki
Punjabi : Karru, kaur
Tamil : Katuka rohini, Katuku rohini, Kadugurohini
Telugu : Karukarohini
Urdu : Kutki
Common Name:Kutki

Uses: Anti-pyretic, anti-malarial, useful in jaundice, carminative, hipatoprotecter. It is a highly potential medicinal herb extensively used in various ailments and diseases both in India and abroad since ancient times. Both white and black varieties are used in herbal medicines and drugs. The drug is useful in cases of dropsy. It is stomachic, cardiac and cerebral tonic, antipyretic, anthelmintic, laxative in small doses, antiemetic, cathartic in large doses; useful in bilous fever, dyspepsia, urinary trouble, asthma, hiccough, blood circulation,burns, liver complaints, paralysis, epilepsy, ringworm infection, scabies and gout.

Adulterants: The transeversely striated hollow rhizome apparently looks like those of Gentiana kurroo Royle and makes a good adulterant to the same.

Some Patents:

  1.  Composition comprising Hovenia dulcis thunb. extract, Lindera ...
  2.  Synergistic phytoceutical compositions
  3. Synergistic phytoceutical compositions
  4. Synergistic phytoceutical compositions
  5. Hepato phyto-nutraceutical synergistic composition
  6. Synergistic phytoceutical compositions
  7. Supportive treatment of liver disease
  8.  Treatment of skin conditions
  9. Hepatoprotective activity of 2′-p-hydroxybenzoylmussaenosidic acid
  10. Liver function improvement formulation 

Publications: About 86 Publications are available from indexed / non index journals. Latest20 are given here


  1. A study of standardized extracts of Picrorhiza kurroa Royle ex Benth in experimental nonalcoholic fatty liver disease.
  2. TLC densitometric quantification of picrosides (picroside-I and picroside-II) in Picrorhiza kurroa and its substitute Picrorhiza scrophulariiflora and their antioxidant studies.
  3. Antioxidant and anti-neoplastic activities of Picrorhiza kurroa extracts.
  4. Online HPLC-DPPH method for antioxidant activity of Picrorhiza kurroa Royle ex Benth. and characterization of kutkoside by ultra-performance LC-electrospray ionization quadrupole time-of-flight mass spectrometry.
  5. Pharmacology and chemistry of a potent hepatoprotective compound Picroliv isolated from the roots and rhizomes of Picrorhiza kurroa royle ex benth. (kutki).
  6. Healing potential of Picrorhiza kurroa (Scrofulariaceae) rhizomes against indomethacin-induced gastric ulceration: a mechanistic exploration.
  7. Whole body protection to lethally irradiated mice by oral administration of semipurified fraction of Podophyllum hexandrum and post irradiation treatment of Picrorhiza kurroa.
  8. Novel lipid-peroxidation- and cyclooxygenase-inhibitory tannins from Picrorhiza kurroa seeds.
  9. Immunomodulatory activity of biopolymeric fraction RLJ-NE-205 from Picrorhiza kurroa.
  10. Cyclooxygenase-2 enzyme inhibitory triterpenoids from Picrorhiza kurroa seeds.
  11. Cryopreservation of shoot tips of Picrorhiza kurroa Royle ex Benth, an indigenous endangered medicinal plant, through vitrification.
  12. Picrorhiza kurroa. Monograph.
  13. Protective effect of Picroliv, the active constituent of Picrorhiza kurroa, against chemical carcinogenesis in mice.
  14. Ex vivo and in vivo investigations of picroliv from Picrorhiza kurroa in an alcohol intoxication model in rats.
  15. Pikuroside: a novel iridoid from Picrorhiza kurroa.
  16. Anti-allergic and anti-anaphylactic activity of picroliv--a standardised iridoid glycoside fraction of Picrorhiza kurroa.
  17. Protective effect of Picroliv from Picrorhiza kurroa against Leishmania donovani infections in Mesocricetus auratus.
  18. Picroliv, the iridoid glycoside fraction of Picrorhiza kurroa, selectively augments human T cell response to mycobacterial protein antigens.
  19. Picrorhiza kurroa (Kutaki) Royle ex Benth as a hepatoprotective agent--experimental & clinical studies.
  20. Immunostimulatory activity of Picrorhiza kurroa leaf extract.


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