Saturday, July 7, 2012

Piper longum Pipli Thippili Pippallu



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Piper longum Linn.
Family: Piperaceae
Assamese: Pipoli

Bengali : Pipul পিপুল, Pipool
Chinese: 荜拔 bì bá
English : Long pepper
French: Poivrier long
German: Bengalischer Pfeffer, Jaborandi-Pfeffer, Langer Pfeffer, Stangenpfeffer
Gujarati : Pipara, Gantoda, Ganthoda, પીપલી
Hindi : Pipara, Pipli पीपलि
Hungarian : Bengáli bors
Indonesian: cabe puyung – currently used mostly in natural medicines (Jamu) in Indonesia, Cabe jawa
Italian: pepe di Marisa, pepe lungo
Kannada : Modikaddi, Hippali ಹಿಪ್ಪಲಿ, Tippali ತಿಪ್ಪಲಿ, Modi
Konkani Pimpli
Malayalam : Kattuthippali, Tippali
Marathi : Pimpli पिम्प्लि
Oriya : Pippali, Bana Pippali
Polish: Pieprz długi
Portugues: Pimenta-longa
Punjabi : Pippali, Magha,  Darrilfilfil, Maghan
Russian: Перец длинный
Sanskrit: Granthika, ग्रन्धिक, Pipli पीपलि
Tamil : Tippili, திபபிலி, Ampu அம்பு, Arisi thippili அரிசித் திப்பிலி, Adimarundu ஆதிமருந்து
Telugu : Pippallu పిప్పళ్ళు,
Thai: ดีปลี dipli
Tibetan: པི་པི་ལིང་། pipiling
Tulu: Ippuli
Turkey: Uzun biber
Urdu : Filfil Daraz, Pippal,  پپلی    Pipli,   پیپل   Pipul
Vietnamese: tiêu lốt


Ayurvedic uses: Sula, Arsha, Gulma, Hikka, Kasa, Krimi, Kshya, Kushta, Pliha roga, Prameha, Swasa, Thrushna, Ama vata, Udara roga, Amadosha, Jvara. The root is plungent, hot, stomachic, laxative, anthelmintic and carminative. The fruit is sweetish, pungent, hot, stomachic, aphrodisiac, alterative, laxative, antidysenteric, emmenagogue, abortifacient, diuretic and tonic. The essential oil is antimicrobial and
anthelmintic. N-isobutyl-deca-trans-2-trans-4-dienamide is antitubercular. Piperine is hypotensive, antipyretic, analeptic, and nerve stimulant.

Fruits—used for diseases of the respiratory tract (cough, bronchitis, asthma); as sedative (in insomnia and epilepsy); as cholagogue (in obstruction of bile duct and bladder), as emmenagogue, as digestive, appetizer and carminative (in indigestion); as general tonic and haematinic (in anaemia, chronic fevers and for improving intellect). Applied locally on muscular pains and inflammations.

Indigestion, colic, amenorrhoea, chills due to menstrual disorders, malaria, headache, muscle stiffness, tingling and numbness, paresis and paralysis. (Medicinal Plants of Myanmar)

Sidha Uses: Suvaiyinmai, Iraippu, Irumal, Aiyappini, Kan Kaadu Mookku noygal

Piper longum was mentioned in Aranya Kanda of Ramayana

131 Published article list of Piper longum
1.    Leishmanicidal Compounds from the Fruits of Piper longum.
Ghosal Sabari; Deb Anindita; Mishra Priyanka; et al.; Planta medica  Volume: 78   Issue: 9   Pages: 906-8   Published: 2012-Jun (Epub 2012 May 10)
2.    In vivo and in vitro Antiasthmatic Studies of Plant Piper longum Linn.
Kaushik Dhirender; Rani Ruby; Kaushik Pawan; et al.; INTERNATIONAL JOURNAL OF PHARMACOLOGY  Volume: 8   Issue: 3   Pages: 192-197   DOI: http://dx.doi.org/10.3923/ijp.2012.192.197   Published: APR 1 2012
3.    Direct shoot regeneration from nodal, internodal and petiolar segments of Piper longum L. and in vitro conservation of indexed plantlets
Rani Dolly; Dantu Prem Kumar; PLANT CELL TISSUE AND ORGAN CULTURE  Volume: http://dx.doi.org/109   Issue: 1   Pages: 9-17   DOI: http://dx.doi.org/10.1007/s11240-011-0068-7   Published: APR 2012
4.    Synthesis of silver nanoparticles using Piper longum leaf extracts and its cytotoxic activity against Hep-2 cell line
Jacob S. Justin Packia; Finu J. S.; Narayanan Anand; COLLOIDS AND SURFACES B-BIOINTERFACES  Volume: 91   Pages: 212-214   DOI: http://dx.doi.org/10.1016/j.colsurfb.2011.11.001   Published: MAR 1 2012
5.    A study on the micro-propagation and antioxidant activity of Piper longum (an important medicinal plant)
Parida Reena; Dhal Yogamaya; JOURNAL OF MEDICINAL PLANTS RESEARCH  Volume: 5   Issue: 32   Pages: 6991-6994   DOI: http://dx.doi.org/10.5897/JMPR11.1067   Published: DEC 30 2011
6.    Simultaneous UFLC-ESI-MS/MS determination of piperine and piperlonguminine in rat plasma after oral administration of alkaloids from Piper longum L.: Application to pharmacokinetic studies in rats
Liu Junhui; Bi Ying; Luo Rong; et al.; JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES  Volume: 879   Issue: 27   Pages: 2885-2890   DOI: http://dx.doi.org/10.1016/j.jchromb.2011.08.018   Published: OCT 1 2011
7.    Overview for various aspects of the health benefits of Piper longum linn. fruit.
Kumar Suresh; Kamboj Jitpal; Suman; et al.; Journal of acupuncture and meridian studies  Volume: 4   Issue: 2   Pages: 134-40   Published: 2011-Jun
8.    Piperine production by endophytic fungus Periconia sp isolated from Piper longum L.
Verma Vijay C.; Lobkovsky Emil; Gange Alan C.; et al.; JOURNAL OF ANTIBIOTICS  Volume: 64   Issue: 6   Pages: 427-431   DOI: http://dx.doi.org/10.1038/ja.2011.27   Published: JUN 2011
9.    Hepatoprotective action of ethanolic extracts of Melia azedarach Linn. and Piper longum Linn and their combination on CCl4 induced hepatotoxicity in rats
Rajeswary H.; Vasuki R.; Samudram P.; et al.; INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY  Volume: 49   Issue: 4   Pages: 276-281   Published: APR 2011
10.    Bioactivity guided isolation of mosquito larvicide from Piper longum
Madhu S. K.; Vijayan V. A.; Shaukath A. K.; ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE  Volume: 4   Issue: 2   Pages: 112-116   DOI: http://dx.doi.org/10.1016/S1995-7645(11)60048-5   Published: FEB 2011
11.    Two new amides with cytotoxic activity from the fruits of Piper longum
Mishra Priyanka; Sinha Sadhna; Guru Santosh Kumar; et al.; JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH  Volume: 13   Issue: 2   Pages: 143-148   Article Number: PII 932889324   DOI: http://dx.doi.org/10.1080/10286020.2010.546789   Published: 2011
12.    Antioxidant Activity of Combined Ethanolic Extract of Eclipta alba and Piper longum Linn.
Ramesh Vasuki; Hari Rajeswary; Pandian Samudram; et al.; Journal of complementary & integrative medicine  Volume: 8   Issue: 1     DOI: http://dx.doi.org/10.2202/1553-3840.1591   Published: 2011 Dec 07
13.    A clinical trial of Pippali (Piper longum Linn.) with special reference to Abheshaja.
Pathak Megha; Vyas Hitesh; Vyas Mahesh Kumar; Ayu  Volume: 31   Issue: 4   Pages: 442-6   Published: 2010-Oct
14.    Studies on the neuroprotective role of Piper longum in C6 glioma induced rats
Subramanian Umadevi; Poongavanam Sharmila; Vanisree A. J.; INVESTIGATIONAL NEW DRUGS  Volume: 28   Issue: 5   Pages: 615-623   DOI: http://dx.doi.org/10.1007/s10637-009-9301-1   Published: OCT 2010
15.    Proteomic evaluation on antiplatelet activity of piperlongumine derived from Piper longum
Lee Sung-Eun; Park Byeoung-Soo; Huh Tae-Lin; et al.; MOLECULAR & CELLULAR TOXICOLOGY  Volume: 6   Issue: 3   Pages: 295-303   DOI: http://dx.doi.org/10.1007/s13273-010-0040-3   Published: SEP 30 2010
16.    Phytotoxicity of Sarmentine Isolated from Long Pepper (Piper longum) Fruit
Huang Huazhang; Morgan Christy M.; Asolkar Ratnakar N.; et al.; JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY  Volume: 58   Issue: 18   Pages: 9994-10000   DOI: http://dx.doi.org/10.1021/jf102087c   Published: SEP 22 2010
17.    Effect of Piper longum Linn. in monosodium glutamate toxicity in rats
Thomas Mariyamma; George Sislamma; INDIAN JOURNAL OF ANIMAL SCIENCES  Volume: 80   Issue: 9   Pages: 857-863   Published: SEP 2010
18.    Inhibitory Effects of Bakuchiol, Bavachin, and Isobavachalcone Isolated from Piper longum on Melanin Production in B16 Mouse Melanoma Cells
Ohno Osamu; Watabe Taeko; Nakamura Kazuhiko; et al.; BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY  Volume: 74   Issue: 7   Pages: 1504-1506   DOI: http://dx.doi.org/10.1271/bbb.100221   Published: JUL 2010
19.    Histological changes and protective effect of pipali (Piper longum) in arsenic intoxicated cockerels
Sajan Ram; Singh S. P.; Varma Rachna; et al.; INDIAN JOURNAL OF ANIMAL SCIENCES  Volume: 80   Issue: 7   Pages: 647-649   Published: JUL 2010
20.    Antiinflammatory Activity of Piper longum Fruit Oil
Kumar A.; Panghal S.; Mallapur S. S.; et al.; INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES  Volume: 71   Issue: 4   Pages: 454-U179   Published: JUL-AUG 2009
21.    Alkamides from Piper longum and Piper nigrum as Inhibitors of IL-6 action
Lee Seung Woong; Kim Myo Sun; Park Mi Hye; et al.; BULLETIN OF THE KOREAN CHEMICAL SOCIETY  Volume: 31   Issue: 4   Pages: 921-924   DOI: http://dx.doi.org/10.5012/bkcs.2010.31.04.921   Published: APR 20 2010
22.    Antimicrobial Activity and HPTLC Profiling of Piper longum Linn. after Microbial Decontamination by Gamma Irradiation
Gupta Prakash Chandra; Garg Neelam; Pant Devki; et al.; JOURNAL OF PURE AND APPLIED MICROBIOLOGY  Volume: 4   Issue: 1   Pages: 69-77   Published: APR 2010
23.    Strong remedies. 3. Piper longum and P. cubeba in Norwegian folk tradition.
Alm Torbjorn; Blyttia  Volume: 68   Issue: 2   Pages: 122-127   Published: 2010
24.    Inhibitory effect of essential oils of Allium sativum and Piper longum on spontaneous muscular activity of liver fluke, Fasciola gigantica
Singh Thakur Uttam; Kumar Dinesh; Tandan Surendra Kumar; et al.; EXPERIMENTAL PARASITOLOGY  Volume: 123   Issue: 4   Pages: 302-308   DOI: http://dx.doi.org/10.1016/j.exppara.2009.08.002   Published: DEC 2009
25.    Antioxidant and antihepatotoxic activities of ethanolic crude extract of Melia azedarach and Piper longum
Samudram P.; Vasuki R.; Rajeshwari H.; et al.; JOURNAL OF MEDICINAL PLANTS RESEARCH  Volume: 3   Issue: 12   Pages: http://dx.doi.org/1078-1083   Published: DEC 2009
26.    [Chemical constituents from Piper longum].
Liu Wenfeng; Jiang Zhiyong; Chen Jijun; et al.; Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica  Volume: 34   Issue: 22   Pages: 2891-4   Published: 2009-Nov
27.    Molluscicidal activity of Piper cubeba Linn., Piper longum Linn. and Tribulus terrestris Linn. and their combinations against snail Indoplanorbis exustus Desh.
Pandey Jitendra K.; Singh D. K.; INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY  Volume: 47   Issue: 8   Pages: 643-648   Published: AUG 2009
28.    Antihyperlipidemic Compounds from the Fruit of Piper longum L.
Jin Zhuang; Borjihan Gereltu; Zhao Ruiguo; et al.; PHYTOTHERAPY RESEARCH  Volume: 23   Issue: 8   Pages: 1194-1196   DOI: http://dx.doi.org/10.1002/ptr.2630   Published: AUG 2009
29.    [Chemical constituents from air-dried Piper longum].
Liu Wenfeng; Jiang Zhiyong; Chen Jijun; et al.; Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica  Volume: 34   Issue: 9   Pages: 1101-3   Published: 2009-May
30.    Hepatoprotective activity of Piper longum traditional milk extract on carbon tetrachloride induced liver toxicity in Wistar rats
Patel Jagruti A.; Shah Urvi S.; BOLETIN LATINOAMERICANO Y DEL CARIBE DE PLANTAS MEDICINALES Y AROMATICAS  Volume: 8   Issue: 2   Pages: 121-129   Published: MAR 2009
31.    Protective effect of Piper longum Linn. on monosodium glutamate induced oxidative stress in rats
Thomas Mariyamma; Sujatha K. S.; George Sisilamma; INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY  Volume: 47   Issue: 3   Pages: 186-192   Published: MAR 2009
32.    Effects of Piper longum L. on Chills in Japanese Young Women: Time-Dependent Changes in Skin Surface Temperature and Its Recovery Rate Following the Exposure to Mild Cold Stress
Yamada Noriko; Nishihara Chie; Yoshimura Hiroyuki; et al.; Japanese Journal of Neuropsychopharmacology  Volume: 29   Issue: 1   Pages: 7-15   Published: FEB 2009
33.    [Effects of Piper longum L. on chills in Japanese young women: time-dependent changes in skin surface temperature and its recovery rate following the exposure to mild cold stress].
Yamada Noriko; Nishihara Chie; Yoshimura Hiroyuki; et al.; Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology  Volume: 29   Issue: 1   Pages: 7-15   Published: 2009-Feb
34.    Protective effect of Piper longum fruits against experimental myocardial oxidative stress induced injury in rats
Wakade Alok S.; Shah Abhishek S.; Kulkarni Mrugaya P.; et al.; Journal of Natural Remedies  Volume: 9   Issue: 1   Pages: 43-50   Published: JAN 2009
35.    THE ISOLATION, CHARACTERISATION AND ANTI-MICROBIAL ACTIVITY OF ALKALOIDS OF JATROPHA CURCAS AND PIPER LONGUM
Chaturvedi Pratibha; Journal of Phytological Research  Volume: 21   Issue: 1   Pages: 53-56   Published: 2008
36.    Alkamides from the fruits of Piper longum and Piper nigrum displaying potent cell adhesion inhibition
Lee Seung Woong; Kim Young Kook; Kim Koanhoi; et al.; BIOORGANIC & MEDICINAL CHEMISTRY LETTERS  Volume: 18   Issue: 16   Pages: 4544-4546   DOI: http://dx.doi.org/10.1016/j.bmcl.2008.07.045   Published: AUG 15 2008
37.    Ameliorative effect of Piper longum fruits against experimental myocardial oxidative stress-induced injury in rats
Wakade A. S.; Juvekar A. R.; Kulkarni M. P.; et al.; PLANTA MEDICA  Volume: 73   Issue: 9   Pages: 962-962   Meeting Abstract: P442   Published: AUG 2007
38.    PIPUL (PIPER LONGUM LINN.) - ETHNOMEDICINAL USES AND PROPAGATION IN SOUTH BENGAL
Chaudhuri Saurabh; Das Indrani; Indian Forester  Volume: 134   Issue: 8   Pages: 1105-1107   Published: AUG 2008
39.    Antiinflammatory activity of the fruits of Piper longum Linn
Bhitre M. J.; Fulmali Sushma; Kataria Maya; et al.; ASIAN JOURNAL OF CHEMISTRY  Volume: 20   Issue: 6   Pages: 4357-4360   Published: JUL-AUG 2008
40.    Protective effect of Piper longum L. on oxidative stress induced injury and cellular abnormality in adriamycin induced cardiotoxicity in rats
Wakade Alok S.; Shah Abhishek S.; Kulkarni Mrugaya P.; et al.; INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY  Volume: 46   Issue: 7   Pages: 528-533   Published: JUL 2008
41.    Cardiovascular action of Piper longum
Inchan A.; Promma P.; Chintana P.; et al.; PLANTA MEDICA  Volume: 74   Issue: 9   Pages: 942-942   Published: JUL 2008
42.    Anti-stress, nootropic and anticonvulsant potential of fruit extracts of Piper longum L
Juvekar M. R.; Kulkarni M. P.; Juvekar A. R.; PLANTA MEDICA  Volume: 74   Issue: 9   Pages: http://dx.doi.org/1000-1001   Published: JUL 2008
43.    Methylpiperate derivatives from Piper longum and their inhibition of monoamine oxidase
Lee Seon A.; Hwang Ji Sang; Han Xiang Hua; et al.; ARCHIVES OF PHARMACAL RESEARCH  Volume: 31   Issue: 6   Pages: 679-683   DOI: http://dx.doi.org/10.1007/s12272-001-1212-7   Published: JUN 2008
44.    Toxicity of Piper cubera, Piper longum and Tribulus terrestris against the snail Lymnaea acuminata
Jitendra K. P.; Singh D. K.; Malaysian Applied Biology  Volume: 37   Issue: 1   Pages: 41-46   Published: JUN 2008
45.    Paralytic effect of alcoholic extract of Allium sativium and Piper longum on liver amphistome, Gigantocotyle explanatum
Singh T. U.; Kumar D.; Tandan S. K.; INDIAN JOURNAL OF PHARMACOLOGY  Volume: 40   Issue: 2   Pages: 64-68   Published: APR 2008
46.    Piper longum Linn. Extract inhibits TNF-alpha-induced expression of cell adhesion molecules by inhibiting NF-kappa B activation and microsomal lipid peroxidation
Singh Naresh; Kumar Sarvesh; Singh Prabhjot; et al.; PHYTOMEDICINE  Volume: 15   Issue: 4   Pages: 284-291   DOI: http://dx.doi.org/10.1016/j.phymed.2007.06.007   Published: APR 2008
47.    HPLC assisted chemobiological standardization of alpha-glucosidase-I enzyme inhibitory constituents from Piper longum Linn-An Indian medicinal plant
Pullela Srinivas V.; Tiwari Ashok K.; Vanka UmaMaheswara S.; et al.; JOURNAL OF ETHNOPHARMACOLOGY  Volume: http://dx.doi.org/108   Issue: 3   Pages: 445-449   DOI: http://dx.doi.org/10.1016/j.jep.2006.06.004   Published: DEC 6 2006
48.    Antiplatelet effects of acidamides isolated from the fruits of Piper longum L.
Park B. -S.; Son D. -J.; Park Y. -H.; et al.; PHYTOMEDICINE  Volume: 14   Issue: 12   Pages: 853-855   DOI: http://dx.doi.org/10.1016/j.phymed.2007.06.011   Published: DEC 2007
49.    GC-MS analysis of the essential oils of Piper nigrum L. and Piper longum L.
Liu Ling; Song Guoxin; Hue Yaoming; CHROMATOGRAPHIA  Volume: 66   Issue: 9-10   Pages: 785-790   DOI: http://dx.doi.org/10.1365/s10337-007-0408-2   Published: NOV 2007
50.    Piperlongumine, a constituent of Piper longum L., inhibits rabbit platelet aggregation as a thromboxane A(2) receptor antagonist
Iwashita Masaya; Oka Nobuaki; Ohkubo Satoko; et al.; EUROPEAN JOURNAL OF PHARMACOLOGY  Volume: 570   Issue: 1-3   Pages: 38-42   DOI: http://dx.doi.org/10.1016/j.ejphar.2007.05.073   Published: SEP 10 2007
51.    Inhibitory effect of ethanol extract of Piper longum L. on rabbit platelet aggregation through antagonizing thromboxane A(2) receptor
Iwashita Masaya; Saito Masaki; Yamaguchi Yasunaga; et al.; BIOLOGICAL & PHARMACEUTICAL BULLETIN  Volume: 30   Issue: 7   Pages: 1221-1225   DOI: http://dx.doi.org/10.1248/bpb.30.1221   Published: JUL 2007
52.    Rapid structural determination of amides in Piper longum by high-performance liquid chromatography combined with ion trap mass spectrometry
Sun Cuirong; Pei Saifeng; Pan Yuanjiang; et al.; RAPID COMMUNICATIONS IN MASS SPECTROMETRY  Volume: 21   Issue: 9   Pages: 1497-1503   DOI: http://dx.doi.org/10.1002/rcm.2986   Published: 2007
53.    Inhibition of diacylglycerol acyltransferase by alkamides isolated from the fruits of Piper longum and Piper nigrum
Lee Seung Woong; Rho Mun-Chual; Park Hye Ran; et al.; JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY  Volume: 54   Issue: 26   Pages: 9759-9763   DOI: http://dx.doi.org/10.1021/jf061402e   Published: DEC 27 2006
54.    Discrimination of Piper longum and Piper retrofracturn fruits by chromatographic fingerprint analysis
Bauer R.; Stohr J.; PLANTA MEDICA  Volume: 72   Issue: 11   Pages: http://dx.doi.org/1079-1079   Meeting Abstract: P331   Published: SEP 2006
55.    Piper longum inhibits VEGF and proinflammatory cytokines and tumor-induced angiogenesis in C57BL/6 mice
Sunila ES; Kuttan G; INTERNATIONAL IMMUNOPHARMACOLOGY  Volume: 6   Issue: 5   Pages: 733-741   DOI: http://dx.doi.org/10.1016/j.intimp.2005.10.013   Published: MAY 2006
56.    A simple and convenient method of standardization of Piper longum - An Ayurvedic medicinal plant
Sarma V. Uma Maheswara; Srinivas Pullela V.; Anuradha V.; et al.; JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC  Volume: 19   Issue: http://dx.doi.org/109   Pages: 238-240   DOI: http://dx.doi.org/10.1556/JPC.19.2006.3.13   Published: MAY-JUN 2006
57.    Antifertility activity of Piper longum Linn. in female rats
Lakshmi V; Kumar R; Agarwal SK; et al.; NATURAL PRODUCT RESEARCH  Volume: 20   Issue: 3   Pages: 235-239   DOI: http://dx.doi.org/10.1080/14786410500045465   Published: MAR 2006
58.    Inhibition of CCl4-induced liver fibrosis by Piper longum Linn.?
Christina AJM; Saraswathy GR; Robert SJH; et al.; PHYTOMEDICINE  Volume: 13   Issue: 3   Pages: 196-198   DOI: http://dx.doi.org/10.1016/j.phymed.2004.01.009   Published: FEB 2006
59.    Characterization of Cucumber mosaic virus infecting Indian long pepper (Piper longum L.) and betel vine (Piper betle L.) in India
Hareesh P. S.; Madhubala R.; Bhat A. I.; Indian Journal of Biotechnology  Volume: 5   Issue: 1   Pages: 89-93   Published: JAN 2006
60.    Novel aromatic ester from Piper longum and its analogues inhibit expression of cell adhesion molecules on endothelial cells
Kumar S; Arya P; Mukherjee C; et al.; BIOCHEMISTRY  Volume: 44   Issue: 48   Pages: 15944-15952   DOI: http://dx.doi.org/10.1021/bi050941u   Published: DEC 6 2005
61.    Protective effect of Piper longum fruit ethanolic extract on radiation induced damages in mice: A preliminary study
Sunila ES; Kuttan G; FITOTERAPIA  Volume: 76   Issue: 7-8   Pages: 649-655   DOI: http://dx.doi.org/10.1016/j.fitote.2005.08.008   Published: DEC 2005
62.    Alteration of pharmacokinetics of oxytetracycline following oral administration of Piper longum in hens.
Singh M; Varshneya C; Telang R S; et al.; Journal of veterinary science  Volume: 6   Issue: 3   Pages: 197-200   Published: 2005-Sep
63.    Piperine from the fruits of Piper longum with inhibitory effect on monoamine oxidase and antidepressant-like activity
Lee SA; Hong SS; Han XH; et al.; CHEMICAL & PHARMACEUTICAL BULLETIN  Volume: 53   Issue: 7   Pages: 832-835   DOI: http://dx.doi.org/10.1248/cpb.53.832   Published: JUL 2005
64.    [Study on proliferation effect of extracts of Piper longum on mesenchymal stem cells of rat bone marrow and the relationship to chemical functional groups].
Li Xican; Zhou Jianhong; Li Hui; et al.; Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials  Volume: 28   Issue: 7   Pages: 570-4   Published: 2005-Jul
65.    Development of sex specific molecular markers in dioecious piper longum.L plants by differential display
Manoj P.; Banerjee N.S.; Ravichandran P.; Journal of Applied Information Technology  Volume: 4   Issue: 5   Pages: 459-65   Published: 01 2005
66.    Effects of tea containing Hihatsu (Piper longum) extract on cold constitution
Nagatome Y; Hirayama Y; Ito T; et al.; JOURNAL OF PHARMACOLOGICAL SCIENCES  Volume: 97   Supplement: 1   Pages: 115P-115P   Published: 2005
67.    Piperlonguminine from Piper longum with inhibitory effects on alpha-melanocyte-stimulating hormone-induced melanogenesis in melanoma B16 cells
Min KR; Kim KS; Ro JS; et al.; PLANTA MEDICA  Volume: 70   Issue: 12   Pages: 1115-1118   DOI: http://dx.doi.org/10.1055/s-2004-835836   Published: DEC 2004
68.    Guineensine, an Acyl-CoA: cholesterol acyltransferase inhibitor, from the fruits of Piper longum
Lee SW; Rho MC; Nam JY; et al.; PLANTA MEDICA  Volume: 70   Issue: 7   Pages: 678-679   DOI: http://dx.doi.org/10.1055/s-2004-827193   Published: JUL 2004
69.    Preparative isolation and purification of amides from the fruits of Piper longum L. by upright counter-current chromatography and reversed-phase liquid chromatography
Wu SH; Sun CR; Pei SF; et al.; JOURNAL OF CHROMATOGRAPHY A  Volume: http://dx.doi.org/1040   Issue: 2   Pages: 193-204   DOI: http://dx.doi.org/10.1016/j.chroma.2004.03.056   Published: JUN 25 2004
70.    Effects of Piper longum fruit, Piper sarmentosum root and Quercus infectoria nut gall on caecal amoebiasis in mice
Sawangjaroen N; Sawangjaroen K; Poonpanang P; JOURNAL OF ETHNOPHARMACOLOGY  Volume: 91   Issue: 2-3   Pages: 357-360   DOI: http://dx.doi.org/10.1016/j.jep.2004.01.014   Published: APR 2004
71.    Occurrence and identification of a Cucumber mosaic virus isolate infecting Indian tong pepper (Piper longum)
Bhat A. I.; Sarma Y. R.; Sreenivasulu P.; et al.; Journal of Medicinal and Aromatic Plant Sciences  Volume: 26   Issue: 2   Pages: 279-284   Published: April 2004
72.    Immunomodulatory and antitumor activity of Piper longum Linn. and piperine
Sunila ES; Kuttan G; JOURNAL OF ETHNOPHARMACOLOGY  Volume: 90   Issue: 2-3   Pages: 339-346   DOI: http://dx.doi.org/10.1016/j.jep.2003.10.016   Published: FEB 2004
73.    Antifungal activity of piperoctadecalidine, a piperidine alkaloid derived from long pepper, Piper longum L., against phytopathogenic fungi.
Park Byeoung-Soo; Choi Won-Sik; Lee Sung-Eun; Agricultural Chemistry and Biotechnology  Volume: 46   Issue: 2   Pages: 73-75   Published: June 2003
74.    Analgesic activity of Piper longum Linn. root.
Vedhanayaki G; Shastri Geetha V; Kuruvilla Alice; Indian journal of experimental biology  Volume: 41   Issue: 6   Pages: 649-51   Published: 2003-Jun
75.    Potential antiamoebic property of the roots of Piper longum Linn
Ghoshal S; Lakshmi V; PHYTOTHERAPY RESEARCH  Volume: 16   Issue: 7   Pages: 689-691   DOI: http://dx.doi.org/10.1002/ptr.1014   Published: NOV 2002
76.    In vitro micropropagation of Piper longum - an important medicinal plant
Soniya EV; Das MR; PLANT CELL TISSUE AND ORGAN CULTURE  Volume: 70   Issue: 3   Pages: 325-327   DOI: http://dx.doi.org/10.1023/A:1016561521050   Published: SEP 2002
77.    Inhibition of aflatoxin B-1 biosynthesis by piperlongumine isolated from Piper longum L.
Lee SE; Mahoney NE; Campbell BC; JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY  Volume: 12   Issue: 4   Pages: 679-682   Published: AUG 2002
78.    A piperidine amide extracted from Piper longum L. fruit shows activity against Aedes aegypti mosquito larvae
Yang YC; Lee SG; Lee HK; et al.; JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY  Volume: 50   Issue: 13   Pages: 3765-3767   DOI: http://dx.doi.org/10.1021/jf011708f   Published: JUN 19 2002
79.    Insecticidal and acaricidal activity of pipernonaline and piperoctadecalidine derived from dried fruits of Piper longum L.
Park BS; Lee SE; Choi WS; et al.; CROP PROTECTION  Volume: 21   Issue: 3   Pages: 249-251   Article Number: PII S0261-2194(01)00079-5   DOI: http://dx.doi.org/10.1016/S0261-2194(01)00079-5   Published: APR 2002
80.    Fungicidal activity of pipernonaline, a piperidine alkaloid derived from long pepper, Piper longum L., against phytopathogenic fungi
Lee SE; Park BS; Kim MK; et al.; CROP PROTECTION  Volume: 20   Issue: 6   Pages: 523-528   DOI: http://dx.doi.org/10.1016/S0261-2194(00)00172-1   Published: JUL 2001
81.    Antibacterial activity of isolates from Piper longum and Taxus baccata
Reddy PS; Jamil K; Madhusudhan P; et al.; PHARMACEUTICAL BIOLOGY  Volume: 39   Issue: 3   Pages: 236-238   Published: JUN 2001
82.    Tetrahydropiperine, the first natural aryl pentanamide from Piper longum
Madhusudhan P; Vandana KL; BIOCHEMICAL SYSTEMATICS AND ECOLOGY  Volume: 29   Issue: 5   Pages: 537-538   DOI: http://dx.doi.org/10.1016/S0305-1978(00)00083-1   Published: MAY 2001
83.    Effect of Piper longum Linn, Zingiber officianalis Linn and Ferula species on gastric ulceration and secretion in rats
Agrawal A. K.; Rao Ch. V.; Sairam K.; et al.; Indian Journal of Experimental Biology  Volume: 38   Issue: http://dx.doi.org/10   Pages: 994-998   Published: October, 2000
84.    Fruit oil composition of Piper chaba Hunt., P-longum L. and P-nigrum L.
Tewtrakul S; Hase K; Kadota S; et al.; JOURNAL OF ESSENTIAL OIL RESEARCH  Volume: 12   Issue: 5   Pages: 603-608   Published: SEP-OCT 2000
85.    Mosquito larvicidal activity of pipernonaline, a piperidine alkaloid derived from long pepper, Piper longum
Lee SE; JOURNAL OF THE AMERICAN MOSQUITO CONTROL ASSOCIATION  Volume: 16   Issue: 3   Pages: 245-247   Published: SEP 2000
86.    Genetic variation and micropropagation in three varieties of Piper longum L.
Philip S; Banerjee NS; Das MR; CURRENT SCIENCE  Volume: 78   Issue: 2   Pages: 169-173   Published: JAN 25 2000
87.    Antigiardial and immunostimulatory effect of Piper longum on giardiasis due to Giardia lamblia
Tripathi DM; Gupta N; Lakshmi V; et al.; PHYTOTHERAPY RESEARCH  Volume: 13   Issue: 7   Pages: 561-565   DOI: http://dx.doi.org/10.1002/(SICI)1099-1573(199911)13:7<561::AID-PTR479>3.3.CO;2-N   Published: NOV 1999
88.    Male-sex-associated RAPD markers in Piper longum L.
Banerjee NS; Manoj P; Das MR; CURRENT SCIENCE  Volume: 77   Issue: 5   Pages: 693-695   Published: SEP 10 1999
89.    Male-sex-associated RAPD markers in Piper longum L
Banerjee N. S.; Manoj P.; Das M. R.; Current Science (Bangalore)  Volume: 77   Issue: 5   Pages: 693-695   Published: Sept. 10, 1999
90.    Toxicity studies in mice of common spices, Cinnamomum zeylanicum bark and Piper longum fruits
Shah AH; Al-Shareef AH; Ageel AM; et al.; PLANT FOODS FOR HUMAN NUTRITION  Volume: 52   Issue: 3   Pages: 231-239   DOI: http://dx.doi.org/10.1023/A:1008088323164   Published: 1998
91.    Futoamide from Piper longum
Das B; Kashinatham A; FITOTERAPIA  Volume: 69   Issue: 6   Pages: 548-548   Published: 1998
92.    Application of RAPD fingerprinting in selection of micropropagated plants of Piper longum for conservation
Parani M; Anand A; Parida A; CURRENT SCIENCE  Volume: 73   Issue: 1   Pages: 81-83   Published: JUL 10 1997
93.    Characterisation of chemical constituents of Indian long pepper (Piper longum L)
Shankaracharya NB; Rao LJ; Naik JP; et al.; JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE  Volume: 34   Issue: 1   Pages: 73-75   Published: JAN-FEB 1997
94.    Alkamides and other constituents of Piper longum
Das Biswanath; Kashinatham A.; Srinivas K. V. N. S.; Planta Medica  Volume: 62   Issue: 6   Pages: 582   DOI: http://dx.doi.org/10.1055/s-2006-957982   Published: 1996
95.    Alkamides and other constituents of Piper longum
GonzalezLaredo RF; Karchesy JJ; PLANTA MEDICA  Volume: 62   Issue: 6   Pages: 582-582   DOI: http://dx.doi.org/10.1055/s-2006-957983   Published: DEC 1996
96.    Antiamoebic activity of Piper longum fruits against Entamoeba histolytica in vitro and in vivo
Ghoshal S; Prasad BNK; Lakshmi V; JOURNAL OF ETHNOPHARMACOLOGY  Volume: 50   Issue: 3   Pages: 167-170   DOI: http://dx.doi.org/10.1016/0378-8741(96)01382-7   Published: MAR 1996
97.    A new dimer of amide from Piper longum
Zhang Ke Chen Chang-Xiang; Wang De-Zu; Wu Yu; Acta Botanica Yunnanica  Volume: 18   Issue: 3   Pages: 353-355   Published: 1996
98.    A new dimer of amide from Piper longum
Zhang Ke Chen Chang-Xiang; Wang De-Zu; Wu Yu; Acta Botanica Yunnanica  Volume: 18   Issue: 3   Pages: 353-355   Published: 1996
99.    PLANT-REGENERATION FROM CALLUS-CULTURES OF PIPER-LONGUM L BY ORGANOGENESIS
BHAT SR; KACKAR A; CHANDEL KPS; PLANT CELL REPORTS  Volume: 11   Issue: http://dx.doi.org/10   Pages: 525-528   Published: SEP 1992
100.    Plant regeneration from callus cultures of Piper longum L. by organogenesis
Bhat S. R.; Kackar A.; Chandel K. P. S.; Plant Cell Reports  Volume: 11   Issue: http://dx.doi.org/10   Pages: 525-528   Published: 1992
101.    OCCURRENCE OF HELOPELTIS-THEIVORA WATERHOUSE (MIRIDAE, HEMIPTERA) AS A PEST OF INDIAN LONG PEPPER PIPER-LONGUM LINN
ABRAHAM CC; ENTOMON  Volume: 16   Issue: 3   Pages: 245-246   Published: SEP 1991
102.    AFLATOXIN PRODUCTION ON PIPER-LONGUM FRUITS UNDER DIFFERENT TEMPERATURES
ROY A K; CHOURASIA H K; International Journal of Crude Drug Research  Volume: 28   Issue: 3   Pages: 233-235   Published: 1990
103.    EFFECT OF RELATIVE HUMIDITY ON FUNGAL ASSOCIATION AND AFLATOXIN PRODUCTION IN PIPER-LONGUM FRUITS
CHOURASIA H K; ROY A K; Indian Botanical Reporter  Volume: 8   Issue: 2   Pages: 138-140   Published: 1989
104.    ARISTOLACTAMS AND 4,5-DIOXOAPORPHINES FROM PIPER-LONGUM
DESAI SJ; PRABHU BR; MULCHANDANI NB; PHYTOCHEMISTRY  Volume: 27   Issue: 5   Pages: 1511-1515   DOI: http://dx.doi.org/10.1016/0031-9422(88)80226-7   Published: 1988
105.    DEHYDROPIPERNONALINE, AN AMIDE POSSESSING CORONARY VASODILATING ACTIVITY, ISOLATED FROM PIPER-LONGUM L
SHOJI N; UMEYAMA A; SAITO N; et al.; JOURNAL OF PHARMACEUTICAL SCIENCES  Volume: 75   Issue: 12   Pages: 1188-1189   DOI: http://dx.doi.org/10.1002/jps.2600751215   Published: DEC 1986
106.    PIPER-LONGUM L - A NEW HOST RECORD FOR COLLECTOTRICHUM-
GLOEOSPORIOIDES PENZ
SATHYARAJAN PK; NASEEMA A; CURRENT SCIENCE  Volume: 54   Issue: 13   Pages: 637-637   Published: 1985
107.    EVALUATION OF ANTIALLERGIC ACTIVITY OF PIPER-LONGUM
DAHANUKAR S A; KARANDIKAR S M; Indian Drugs  Volume: 21   Issue: 9   Pages: 377-383   Published: 1984
108.    EFFICACY OF PIPER-LONGUM IN CHILDHOOD ASTHMA
DAHANUKAR S A; KARANDIKAR S M; DESAI M; Indian Drugs  Volume: 21   Issue: 9   Pages: 384-388   Published: 1984
109.    HEPATOPROTECTIVE EFFECTS OF PIPER-LONGUM AGAINST CARBON TETRACHLORIDE INDUCED LIVER DAMAGE
REGE N; DAHANUKAR S; KARANDIKAR S M; Indian Drugs  Volume: 21   Issue: 12   Pages: 569-580   Published: 1984
110.    [Introduction and propagation of Piper longum].
Zuo C Q; Zhong yao tong bao (Beijing, China : 1981)  Volume: 8   Issue: 3   Pages: 5-7   Published: 1983-May
111.    STUDIES ON THE CONSTITUENTS OF THE CRUDE DRUG PIPERIS-LONGI FRUCTUS - ON THE ALKALOIDS OF FRUITS OF PIPER-LONGUM L
TABUNENG W; BANDO H; AMIYA T; CHEMICAL & PHARMACEUTICAL BULLETIN  Volume: 31   Issue: http://dx.doi.org/10   Pages: 3562-3565   Published: 1983
112.    ANTI FERTILITY EFFECT OF EMBELIA-RIBES AND PIPER-LONGUM IN FEMALE RATS
GARG S K; Fitoterapia  Volume: 52   Issue: 4   Pages: 167-170   Published: 1982
113.    PROTECTIVE EFFECT OF PIPER-LONGUM AGAINST HEPATIC DAMAGE
REGE N N; DAHANUKAR S A; KARANDIKAR S M; et al.; Indian Journal of Pharmacology  Volume: 14   Issue: 1   Pages: 63-64   Published: 1982
114.    ANTI-FERTILITY EFFECTS OF THE FRUITS OF PIPER-LONGUM IN FEMALE RATS
KHOLKUTE SD; KEKARE MB; MUNSHI SR; INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY  Volume: 17   Issue: 3   Pages: 289-290   Published: 1979
115.    CHEMICAL AND SOME PHARMACOLOGICAL STUDIES ON LEAVES OF PIPER-LONGUM
MANAVALAN R; SINGH J; Indian Journal of Pharmaceutical Sciences  Volume: 41   Issue: 5   Pages: 190-191   Published: 1979
116.    STUDIES ON GENUS PIPER - STUDIES ON ROOTS OF PIPER-LONGUM-LINN
DUTTA CP; BANERJEE N; SIL AK; INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY  Volume: 15   Issue: 6   Pages: 583-584   Published: 1977
117.    INTRA PLASTOCHRONIC CHANGES IN SHOOT APICAL MERISTEM OF PIPER-LONGUM
DASGUPTA A; DATTA P C; Bulletin of the Botanical Society of Bengal  Volume: 31   Issue: 1-2   Pages: 1-4   Published: 1977
118.    STUDIES ON GENUS PIPER .3. LIGNANS IN SEEDS OF PIPER-LONGUM
DUTTA CP; BANERJEE N; ROY DN; PHYTOCHEMISTRY  Volume: 14   Issue: 9   Pages: 2090-2091   DOI: http://dx.doi.org/10.1016/0031-9422(75)83139-6   Published: 1975
119.    STUDIES ON THE GENUS PIPER III CHEMICAL INVESTIGATION OF THE SEEDS OF PIPER-LONGUM PIPERACEAE
DUTTA C P; BANERJEE N; Indian Science Congress Association Proceedings  Volume: 62   Pages: http://dx.doi.org/101   Published: 1975
120.    CHARACTERIZATION OF UNUSUAL REACTION PRODUCTS DURING THE SYNTHESIS OF N ISO BUTYL DECA-TRANS-2-TRANS-4-DIENAMIDE AN AMIDE ALKALOID OF PIPER-LONGUM
KUNDU A B; DESMUKJ S K; Indian Science Congress Association Proceedings  Volume: 62   Pages: http://dx.doi.org/107   Published: 1975
121.    CHARACTERIZATION OF UNUSUAL REACTION PRODUCTS DURING THE SYNTHESIS OF N ISO BUTYL DECA-TRANS-2-TRANS-4-DIENAMIDE AN AMIDE ALKALOID OF PIPER-LONGUM
KUNDU A B; DESMUKJ S K; Indian Science Congress Association Proceedings  Volume: 62   Pages: http://dx.doi.org/107   Published: 1975
122.    ANTI BACTERIAL ACTIVITY OF SOME ESSENTIAL OILS ALPINIA-GALANGA-M NIGELLA-SATIVA-D PIPER-LONGUM-D VATERIA-INDICA-D SACCOPETALUM-TOMENTOSUM-D BACILLUS-CEREUS BACILLUS-SUBTILIS STAPHYLOCOCCUS-ALBUS STAPHYLOCOCCUS-AUREUS SARCINA-LUTEA SHIGELLA DYSENTERIAE ESCHERICHIA-COLI SHIGELLA-BOYDII SALMONELLA-TYPHI VIBRIO-CHOLERAE
BHARGAVE A K; CHAUHAN C S; Indian Journal of Pharmacy  Volume: 30   Issue: 6   Pages: 150-151   Published: 1968
123.    ON STRUCTURE OF PIPLARTINE AND A SYNTHESIS OF DIHYDROPIPLARTINE
JOSHI BS; KAMAT VN; SAKSENA AK; TETRAHEDRON LETTERS  Issue: 20   Pages: 2395-&   Published: 1968
124.    ALKALOIDS OF PIPER LONGUM LINN .I. STRUCTURE AND SYNTHESIS OF PIPERLONGUMINE AND PIPERLONGUMININE
CHATTERJ.A; DUTTA CP; TETRAHEDRON  Volume: 23   Issue: 4   Pages: 1769-&   DOI: http://dx.doi.org/10.1016/S0040-4020(01)82575-8   Published: 1967
125.    OCCURRENCE OF N-ISOBUTYLDECA-TRANS-2-TRANS-4-DIENAMIDE IN PIPER LONGUM LINN + PIPER PEEPULOIDES ROYLE
DHAR KL; ATAL CK; INDIAN JOURNAL OF CHEMISTRY  Volume: 5   Issue: 11   Pages: 588-&   Published: 1967
126.    OCCURRENCE OF SESAMIN IN PIPER LONGUM LINN
ATAL CK; GIROTRA RN; DHAR KL; INDIAN JOURNAL OF CHEMISTRY  Volume: 4   Issue: 5   Pages: 252-&   Published: 1966
127.    STRUCTURE OF PIPERLONGUMININE AN ALKALOID OF PIPER LONGUM LINN
CHATTERJ.A; DUTTA CP; TETRAHEDRON LETTERS  Issue: 16   Pages: 1797-&   Published: 1966
128.    Structure of piperlonguminine, an alkaloid of Piper longum Linn [Dried unripe fruit, oil, starch, proteins
CHATTERJEE A.; DUTTA C. P.; TETRAHEDRON LETT  Volume: 16   Pages: 1797-1800   Published: 1966
129.    Preliminary observations on the effect of Piper longum and Piper nigrum on growth-rate
SHARMA P. V.; CHATURVEDI C.; J MED SCI BANARAS HINDU UNIV  Volume: 5   Issue: (1)   Pages: 51-57   Published: 1964
130.    STRUCTURE OF PIPLARTINE - A NEW ALKALOID FROM PIPER LONGUM
ATAL CK; BANGA SS; CURRENT SCIENCE  Volume: 32   Issue: 8   Pages: 354-&   Published: 1963
131.    Developmental studies: VL The morphology of the so-called stipule of Piper (Piperaceae) from a comparative ontogenetical study of this structure in Piper betle, Piper longum, Piper nigrum, Piper ornatum and two other species of Piper and the morphology of the leaf-sheath of Scindapsus officinalis (Araceae)
MAJUMDAR G. P.; PAL PRADYOTKUMAR; PROC NATL INST SCI INDIA PART B BIOL SCI  Volume: 27   Issue: (1)   Pages: 26-39   Published: 1961

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