Family: Oxalidaceae
Synonyms: Biophytum somnulentum Goebel , Biophytum sesbanioides Edgew. & Hook.f. , Biophytum poterioides Edgew. & Hook.f. , Biophytum nervifolium Thwaites , Biophytum homblei De Wild. , Biophytum cumingii Klotzsch , Biophytum cumingianum (Turcz.) Edgew. & Hook.f. , Biophytum candolleanum Wight , Biophytum bogoroense De Wild. , Biophytum bequaertii De Wild.
Chinese: 感应草
Bengali: ঝলৈ jhalai
Hindi: alm bhusha, लज्जालू lajjaalu, lakshmana
Kannada: hara muni, jalapushpa
Malayalam: മുക്കുറ്റി mukkutti
Marathi: झरेरा jharera, लाजवंती lajwanti
Sanskrit: झुल्लिपुष्प jhullipuspa, लजालू lajalu, पङ्क्तिपत्र panktipatra, pitapushpa, vipareetalajjaalu, alambusha, jalapushpa, peethapushpa, samanga, krithanjali
Tamil: nilaccurunki, tintaanaalee
Telugu: attapatti, chumi, jala puspa, పులిచింత pulicenta
Uses: Astringent, antipyretic, anti-septic [MEDICINAL PLANTS]
Activities: Analgesic , Antiangiogenic , Antiaphrodisiac , Anticancer , Antiedemic , Antiinflammatory , Antioxidant , Antiseptic , Antisialogogue , Antitumor , Astringent, Bitter, Contraceptive, COXI-Inhibitor, Diuretic, Expectorant, Febrifuge, Hypoglycemic, Insulinotropic, Litholytic, Sterilant, Stimulant, Tonic, Vulnerary .
Indications: Abscesses , Asthma, Biliousness, Bruises, Burns, Cancer, Collapse, Convulsions, Cramps, Dermatosis , Diabetes , Edema , Fever , Gastrosis, Gonorrhea, Hyperglycemia, Infection , Inflammation, Insomnia , Mycobacterium; Pain, Phthisis, Pulmonosis, Spasms, Stomachache, Stones, Strangury, Swelling, Thirst, Tuberculosis, Tumors, VD, Wounds. [Duke’s Handbook of MEDICINAL PLANTS OF LATIN AMERICA]
Rural folk of Orissa and ethnic communities of Sagar district consider the plant as antiexcitant. Bhils use root to decrease sexual vigour; and the ethnic communities of Ratan Mahal Hills (Gujarat) maintain that smoking dried leaves with tobacco reduces the reproductive capabilities of man, and excessive use of the same renders him impotent. Kasis, Jaintias and Santals find different parts of the plant beneficial for diverse diseases. [HERBAL CURES: TRADITIONAL APPROACH]
Plant—used in insomnia, convulsions, cramps, chest-complaints, inflammations, tumours, chronic skin diseases. Ash—in stomachache. Leaves— diuretic, astringent, antiseptic. Paste is applied to burns, contusions and wounds. Decoction is given in strangury, asthma and phthisis. Roots—decoction is given in lithiasis. Mature leaves are recommended in diabetes; contain an insulin-like principle. A saline extract of leaves showed hypoglycaemic activity in rabbits. [Indian Medicinal Plants An Illustrated Dictionary]
36 Published articles of Biophytum sensitivum
1. Fibro-porous polycaprolactone membrane containing extracts of Biophytum sensitivum: A prospective antibacterial wound dressing
Namboodiri, Arjun Govindan; Parameswaran, Ramesh
JOURNAL OF APPLIED POLYMER SCIENCE Volume: 129 Issue: 4 Pages: 2280-2286 Published: AUG 15 2013
2. Bioefficacy of leaf extracts of Biophytum sensitivum (L.) DC. against Aedes aegypti (Diptera : Culicidae)
Shivakumar, M. S.; Natarajan, D.; Srinivasan, R.
RESEARCH JOURNAL OF BIOTECHNOLOGY Volume: 8 Issue: 3 Pages: 67-70 Published: MAR 2013
3. Biophytum sensitivum: Ancient medicine, modern targets.
Sakthivel, K M; Guruvayoorappan, C
Journal of advanced pharmaceutical technology & research Volume: 3 Issue: 2 Pages: 83-91 Published: 2012-Apr
4. Effect of Biophytum sensitivum on streptozotocin and nicotinamide-induced diabetic rats.
Ananda, Prabu K; Kumarappan, Ct; Sunil, Christudas; et al.
Asian Pacific journal of tropical biomedicine Volume: 2 Issue: 1 Pages: 31-5 Published: 2012-Jan
5. Ethnobotany, phytochemistry and pharmacology of Biophytum sensitivum DC.
Bharati, Abinash C; Sahu, Alakh N
Pharmacognosy reviews Volume: 6 Issue: 11 Pages: 68-73 Published: 2012-Jan
6. Effect of Biophytum sensitivum on streptozotocin and nicotinamide-induced diabetic rats
Prabu, Ananda K.; Kumarappan, C. T.; Christudas, Sunil; et al.
Asian Pacific Journal of Tropical Biomedicine Volume: 2 Issue: 1 Pages: 31-35 Published: JAN 2012
7. Effect of Amentoflavone, a Phenolic Component From Biophytum sensitivum, on Cell Cycling and Apoptosis of B16F-10 Melanoma Cells
Siveen, K. S.; Kuttan, Girija
JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY Volume: 30 Issue: 4 Pages: 301-309 Published: 2011
8. Regeneration of Biophytum sensitivum (Linn.) DC. through organogenesis and somatic embryogenesis
Shivanna, M. B.; Vasanthakumari, M. M.; Mangala, M. C.
INDIAN JOURNAL OF BIOTECHNOLOGY Volume: 8 Issue: 1 Pages: 127-131 Published: JAN 2009
9. Biophytum seusitivum (L.) DC inhibits tumor cell invasion and metastasis through a mechanism involving regulation of MMPs, prolyl hydroxylase, lysyl oxidase, nm23, ERK-1, ERK-2, STAT-1, and proinflammatory cytokine gene expression in metastatic lung tissue
Guruvayoorappan, Chandrasekharan; Kuttan, Girija
INTEGRATIVE CANCER THERAPIES Volume: 7 Issue: 1 Pages: 42-50 Published: MAR 2008
10. Methanol extract of Biophytum sensitivum alters the cytokine profile and inhibits iNOS and COX-2 expression in LPS/Con a stimulated macrophages
Guruvayoorappan, Chandrasekharan; Kuttan, Girija
DRUG AND CHEMICAL TOXICOLOGY Volume: 31 Issue: 1 Pages: 175-188 Published: 2008
11. Protective Effect of Biophytum sensitivum (L.) DC on Radiation-Induced Damage in Mice
Guruvayoorappan, C.; Kuttan, Girija
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY Volume: 30 Issue: 4 Pages: 815-835 Published: 2008
12. Anti-metastatic effect of Biophytum sensitivum is exerted through its cytokine and immunomodulatory activity and its regulatory effect on the activation and nuclear translocation of transcription factors in B16F-10 melanoma cells.
Guruvayoorappan, Chandrasekharan; Kuttan, Girija
Journal of experimental therapeutics & oncology Volume: 7 Issue: 1 Pages: 49-63 Published: 2008
13. Apoptotic effect of Biophytum sensitivum on B16F-10 cells and its regulatory effects on nitric oxide and cytokine production on tumor-associated macrophages
Guruvayoorappan, C.; Kuttan, Girija
INTEGRATIVE CANCER THERAPIES Volume: 6 Issue: 4 Pages: 373-380 Published: DEC 2007
14. Immunomodulatory and antitumor activity of Biophytum sensitivum extract
Guruvayoorappan, C.; Kuttan, Girija
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION Volume: 8 Issue: 1 Pages: 27-32 Published: JAN-MAR 2007
15. Evaluation of the chemoprotective effect of Biophytum sensitivum (L.) DC extract against cyclophosphamide induced toxicity in swiss albino mice
Guruvayoorappan, C.; Kuttan, Girija
Drug Metabolism and Drug Interactions Volume: 22 Issue: 2-3 Pages: 131-150 Published: 2007
16. Effect of Biophytum sensitivum on cell-mediated immune response in mice
Guruvayoorappan, C.; Kuttan, G.
IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY Volume: 29 Issue: 3-4 Pages: 337-350 Published: 2007
17. Anti-angiogenic effect of Biophytum sensitivum is exerted through its cytokine modulation activity and inhibitory activity against VEGF mRNA expression, endothelial cell migration and capillary tube formation.
Guruvayoorappan, Chandrasekharan; Kuttan, Girija
Journal of experimental therapeutics & oncology Volume: 6 Issue: 3 Pages: 241-50 Published: 2007
18. Amentoflavone, a biflavonoid from Biophytum sensitivum augments lymphocyte proliferation, natural killer cell and antibody dependent cellular cytotoxicity through enhanced production of IL-2 and IFN-gamma and restrains serum sialic acid and gamma glutamyl transpeptidase production in tumor - bearing animals.
Guruvayoorappan, Chandrasekharan; Kuttan, Girija
Journal of experimental therapeutics & oncology Volume: 6 Issue: 4 Pages: 285-95 Published: 2007
19. Effect of leaf extract of biophytum Sensitivum (LNN.), on fish Labeo rohita
Varsha, Rathod; Chaudhari, U. S.
BRI'S Journal of Advances in Science and Technology Volume: 9 Issue: 1-2 Pages: 77-81 Published: JUN-DEC 2006
20. Antioxidant potential of Biophytum sensitivum extract in vitro and in vivo
Guruvayoorappan, C.; Afira, A. H.; Kuttan, Girija
Journal of Basic and Clinical Physiology and Pharmacology Volume: 17 Issue: 4 Pages: 255-267 Published: 2006
21. Effect of biophytum sensitivum on B16F-10 melanoma cells induced metastasis
[Anonymous]
INDIAN JOURNAL OF MEDICAL RESEARCH Volume: 121 Supplement: S Pages: 128-129 Published: FEB 2005
22. Effect of biophytum sensitivum on B16F-10 melanoma cells induced metastasis
Guruvayoorappan, C.; Kuttan, Girija
Conference: 24th Annual Convention of the Indian-Association-for-Cancer-Research/International Symposium on Human Papillomavirus and Cervical Cancer Location: Noida, INDIA Date: February 09 -12, 2005
Sponsor(s): Indian Assoc Canc Res
Indian Journal of Medical Research Volume: 121 Issue: Suppl. S Pages: 128-129 Published: FEB 2005
23. Hypocholesterolemic effect of Biophytum sensitivum leaf water extract
Puri, D
PHARMACEUTICAL BIOLOGY Volume: 41 Issue: 4 Pages: 253-258 Published: JUN 2003
24. A sensitive HPTLC method for estimation of amentoflavone, a bioactive principle from Biophytum sensitivum (Linn.) DC. and Putranjiva roxburghii wall.
Ravishankara, MN; Pillai, AD; Padh, H; et al.
JPC-JOURNAL OF PLANAR CHROMATOGRAPHY-MODERN TLC Volume: 16 Issue: 3 Pages: 201-205 Published: MAY-JUN 2003
25. Pollen features and germination of Biophytum sensitivum var. sensitivum DC.
Sreedevi, P.; Rekha, B.
Phytomorphology Volume: 53 Issue: 2 Pages: 157-164 Published: April-June 2003
26. Chemical constituents of Biophytum sensitivum.
Lin, Yun-Lian; Wang, Wan-Yi
Chinese Pharmaceutical Journal (Taipei) Volume: 55 Issue: 1 Pages: 71-75 Published: February 2003
27. The insulinotropic activity of a Nepalese medicinal plant Biophytum sensitivum: preliminary experimental study
Puri, D
JOURNAL OF ETHNOPHARMACOLOGY Volume: 78 Issue: 1 Pages: 89-93 Published: NOV 2001
28. Antiinflammatory activity of extracts of Biophytum sensitivum in carrageenin-induced rat paw oedema
Jachak, SM; Bucar, F; Kartnig, T
PHYTOTHERAPY RESEARCH Volume: 13 Issue: 1 Pages: 73-74 Published: FEB 1999
29. Phenolic compounds from Biophytum sensitivum
Bucar, F; Jachak, SM; Karting, T; et al.
PHARMAZIE Volume: 53 Issue: 9 Pages: 651-653 Published: SEP 1998
30. Hypoglycemic effect of biophytum sensitivum in the alloxan diabetic rabbits
Puri, Dinesh; Baral, Nirmal
Indian Journal of Physiology and Pharmacology Volume: 42 Issue: 3 Pages: 401-406 Published: July, 1998
31. Amentoflavone from Biophytum sensitivum and its effect on COX-1/COX-2 catalysed prostaglandin biosynthesis
Bucar, F; Jackak, SM; Noreen, Y; et al.
PLANTA MEDICA Volume: 64 Issue: 4 Pages: 373-374 Published: MAY 1998
32. Application of leaf extract causes repetitive action potentials in Biophytum sensitivum
Sibaoka, T
JOURNAL OF PLANT RESEARCH Volume: 110 Issue: 1100 Pages: 485-487 Published: DEC 1997
33. THE EFFECTS OF TEMPERATURE ON ACTION-POTENTIALS IN THE CHILL SENSITIVE SEISMONASTIC PLANT BIOPHYTUM-SENSITIVUM
JONES, C; WILSON, JM
JOURNAL OF EXPERIMENTAL BOTANY Volume: 33 Issue: 133 Pages: 313-320 Published: 1982
34. A NEW BACTERIAL DISEASE OF BIOPHYTUM SENSITIVUM
PATEL, AM; CHAUHAN, JM; KOTASTHA.WV; et al.
CURRENT SCIENCE Volume: 38 Issue: 11 Pages: 274-& Published: 1969
35. HOMOSTYLY IN HETEROSTYLED BIOPHYTUM SENSITIVUM DC
DEVI, PM; HASHIM, M
JOURNAL OF GENETICS Volume: 59 Issue: 3 Pages: 245-& Published: 1966
36. HETEROSTYLY IN BIOPHYTUM SENSITIVUM DC
DEVI, PM
JOURNAL OF GENETICS Volume: 59 Issue: 1 Pages: 41-& Published: 1964
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