Nigella sativa, Krishnaajira, Karunjeeragam

Nigella sativa L.
Family: Ranunculaceae

• Common name: Black Seed, Fennel flower, Nutmeg flower, Onion seed, Black cumin
• Amharic: ጥቁር አዝሙድ
• Arabic: حبة السوداء
• Bengali: কালো জিরা, কালোজিরা Kalo jira
• Bulgarian: Челебитка посевна
• Catalan: Sanuj
• Croatian: Crni kumin
• Czech: Černý kmín
• Danish: Sortkommen
• Dutch: Zwarte komijn
• Esperanto: Nigelo
• Estonian: Mustköömen
• Finnish: Ryytineito
• French: Nigelle cultivée, Herbe aux épices
• German: Schwarzkümmel
• Hebrew: קצח
• Hindi: कलौंजी, कलोंजी Kalaunji, कालाजीरा
• Hungarian: Feketekömény
• Indonesian: Jinten hitam
• Japanese: ニゲラ
• Kannada: ಕರಿ ಜೀರಿಗೆ kari jirige
• Kazakh: Содана
• Korean: 블랙쿠민
• Latin: Semen Nigellae sive Melanthii
• Latvian: Melnsēklīte
• Lithuanian: Juodgrūdė
• Malay: Jintan hitam
• Malayalam: കരിഞ്ചീരകം karinjirakam
• Norwegian: Svartkarve
• Polish: Czarnuszka siewna
• Romanian: Cernușcă
• Russian: černuška posevnaja, Нигелла
• Sanskrit: कृष्णजीरा Krishnajira
• Sinhalese: Kaluduru
• Slovak: Černuška siata
• Slovenian: Vzhodna črnika
• Spanish: neguilla
• Swedish: Svartkummin
• Thai: เทียนดำ
• Turkish: çörekotu
• Ukrainian: Чорнушка посівна
• Urdu: Kalaunji

Ayurvedic uses: Atisara, Gulma, Adhmaana, Krimiroga (API Vol-1)

Nigella sativa Oil showed prominent in vitro activity against eight MDR strains of Shigella flexneri. [ Clinical Botanical Medicine]

Chronic gastritis, ascariasis, flatulence and malaria [Compendia of World’s Medicinal Flora]

Used in Ayurveda. Powdered seeds paste applied on eczma and  skin  diseases.  Used  for  headache,  rheumatic  pains, asthma and coughs, also applied as a galactagogue, emmenagogue, cooling, tonic, vermifuge and diuretic. Excessive use of seed causes abortion [CRC World Dictionary of  Medicinal and Poisonous Plants]

The seeds of black cumin are used for seasoning and are employed in spice mixes. The odor of crushed seeds has been described as like lemons with a faint suggestion of carrots (Burkill 1935), while the taste is strong, pungent, peppery, rather oddly aromatic, and nutty, "like a cross between poppy seeds and pepper" (Norman 1990). The alternative name nutmeg flower reflects similarity with the strong, agreeable aromatic odor of nutmeg.  The seeds are added to curries, pickles, cheeses, eggs, fish, poultry, meats, game, pickles, conserves,  fruit pies, and confections, particularly cookies, rolls and bread. They are also used to flavor a variety of vegetable dishes. The seeds used to be employed as a substitute for pepper. [Culinary Herbs]

Black cumin, is used in herbal folk medicine all over the world especially in the Middle East, Europe and Asia since antiquity for the treatment and prevention of a number of diseases and disorders that include asthma, bronchitis, diarrhoea, dyslipidaemia, diabetes, hyperglycaemia, and related abnormalities headache, dysentery, infections, obesity, back pain, hypertension, gastrointestinal problems, eczema, boils, rheumatism, cancer, fungal infections, diabetes, hypertension, cardiac diseases, hemorrhoids, sexual diseases and as an abortifacient [ Edible Medicinal and Non-Medicinal Plants Vol-5]

N. sativa was used by Ancient Egyptian and Greek physicians to treat nasal congestion, toothache, as a diuretic to promote menstruation, and to increase milk production,  bronchial asthma, headache, dysentery, infections, obesity, back pain, hypertension, and gastrointestinal problems. [Greco-Arab and Islamic herbal Medicine]

Avicenna used this plant to treat headaches, facial paralysis, and eye cataracts, and when mixed together with honey in hot water to remove bladder and kidney stones. An infusion of the seeds is used to treat toothaches, gastric and intestinal diseases and chest pains, and is used as a, diuretic, sopori fi c, and vermifuge for children (seeds in vinegar), as well as to treat angina and stimulate milk production in women. [The Medicinal Plants of Uzbekistan and Kyrgyzstan]

521 Published articles of Nigella sativa
1.    Effect of dexamethasone and Nigella sativa on peripheral blood eosinophil count, I.a.I.a., cytokine profiles and lung inflammation in murine model of allergic asthma Abbas, Ayman Talatt, et al., The Egyptian journal of immunology / Egyptian Association of Immunologists, 2005. 12(1): p. 95-102.
2.    The biochemical and morphological alterations following administration of melatonin, r.a.a.N.s.i.m.c.a.a.m.A.E.-A., M. A., et al., International Journal of Experimental Pathology, 2005. 86(6): p. 383-396.
3.    The Protective Effects of Nigella sativa Oil and Allium sativum Extract on Amikacin-induced Nephrotoxicity Abdelaziz, I. and M. Kandeel, International Journal of Pharmacology, 2011. 7(6): p. 697-703.
4.    Antinociceptive effects of Nigella sativa oil and its major component, t., in mice Abdel-Fattah, A. F. M., K. Matsumoto, and H. Watanabe, European Journal of Pharmacology, 2000. 400(1): p. 89-97.
5.    Can methanolic extract of Nigella sativa seed affect glyco-regulatory enzymes in experimental hepatocellular carcinoma? Abdel-Hamid, N.M., et al., Environmental Health and Preventive Medicine, 2013. 18(1): p. 49-56.
6.    Effects of Nigella sativa and thymoquinone on biochemical and subcellular changes in pancreatic beta-cells of streptozotocin-induced diabetic rats Abdelmeguid, N.E., et al., Journal of Diabetes, 2010. 2(4): p. 256-266.
7.    Effect of Nigella sativa extract on lymphocyte subsets and serum gamma interferon levels in mice Abdelnoor, A.M., G. Nabulsy, and S. Khairallah, The 9th International Congress of Immunology, 1995: p. 872-872.
8.    Antioxidant property of Nigella sativa (black cumin) and Syzygium aromaticum (clove) in rats during aflatoxicosis Abdel-Wahhab, M.A. and S.E. Aly, Journal of Applied Toxicology, 2005. 25(3): p. 218-223.
9.    Blockade of Nitric Oxide Overproduction and Oxidative Stress by Nigella sativa Oil Attenuates Morphine-Induced Tolerance and Dependence in Mice Abdel-Zaher, A.O., M.S. Abdel-Rahman, and F.M. Elwasei, Neurochemical Research, 2010. 35(10): p. 1557-1565.
10.    Protective effect of Nigella sativa oil against tramadol-induced tolerance and dependence in mice: Role of nitric oxide and oxidative stress Abdel-Zaher, A.O., M.S. Abdel-Rahman, and F.M. Elwasei, Neurotoxicology, 2011. 32(6): p. 725-733.
11.    Improvement of culture of black caraway (Nigella sativa L.) in Kermanshah (Iran) Abdolhamid, P. and B. Sohbat, Planta Medica, 2006. 72(11): p. 1070-1071.
12.    Effect of aqueous-ethanolic extract of Nigella sativa on cisplatin-induced nephrotoxicity in rats Abolfazl, K.R., et al., Clinical Biochemistry, 2011. 44(13): p. S345-S345.
13.    TLC assay of thymoquinone in black seed oil (Nigella sativa Linn) and identification of dithymoquinone and thymol Abou Basha, L.I., M.S. Rashed, and H.Y. Aboul-Enein, Journal of Liquid Chromatography, 1995. 18(1): p. 105-115.
14.    Cytogenetic studies on Nigella sativa seeds extract and thymoquinone on mouse cells infected with schistosomiasis using karyotyping Aboul-Ela, E.I., Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 2002. 516(1-2): p. 11-17.
15.    SIMPLE HPLC METHOD FOR THE DETERMINATION OF THYMOQUINONE IN BLACK SEED OIL (NIGELLA-SATIVA LINN) Aboulenein, H.Y. and L.I. Aboubasha, Journal of Liquid Chromatography, 1995. 18(5): p. 895-902.
16.    Effect of Nigella sativa and Allium cepa oils on Trichinella spiralis in experimentally infected rats Abu El Ezz, N.M.T., Journal of the Egyptian Society of Parasitology, 2005. 35(2): p. 511-523.
17.    Influence of Nigella sativa fixed oil on some blood parameters and histopathology of skin in staphylococcal-infected BALB/c mice Abu-Al-Basal, M.A., Pakistan journal of biological sciences: PJBS, 2011. 14(23): p. 1038-46.
18.    EVALUATION OF THE ANTIMALARIAL AND ANTIOXIDANT ACTIVITIES OF METHANOLIC EXTRACT OF NIGELLA SATIVA IN MICE INFECTED WITH PLASMODIUM YOELLI NIGERIENSIS Ademowo, G.O., et al., American Journal of Tropical Medicine and Hygiene, 2008. 79(6): p. 278-279.
19.    Radiation-modifying abilities of Nigella sativa and Thymoquinone on radiation-induced nitrosative stress in the brain tissue Ahlatci, A., et al., Phytomedicine, 2014. 21(5): p. 740-744.
20.    A review on therapeutic potential of Nigella sativa: A miracle herb Ahmad, A., et al., Asian Pacific Journal of Tropical Biomedicine, 2013. 3(5): p. 337-352.
21.    Physicochemical and phytochemical standardization with HPTLC fingerprinting of Nigella sativa L. seeds Ahmad, A., et al., Pakistan Journal of Pharmaceutical Sciences, 2014. 27(5): p. 1175-1182.
22.    Effect of Nigella sativa and Allium sativum coadminstered with simvastatin in dyslipidemia patients: a prospective, r., double-blind trial Ahmad Alobaidi, Amina Hamed, Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2014. 13(1): p. 68-74.
23.    Study of Nigella sativa oil in the management of wheeze associated lower respiratory tract illness in children Ahmad, J., R.A. Khan, and M.A. Malik, African Journal of Pharmacy and Pharmacology, 2009. 3(5): p. 248-251.
24.    A study of Nigella sativa oil in the management of wheeze associated lower respiratory tract illness in children Ahmad, J., R.A. Khan, and M.A. Malik, African Journal of Pharmacy and Pharmacology, 2010. 4(7): p. 436-439.
25.    Elucidation of mechanisms of actions of thymoquinone-enriched methanolic and volatile oil extracts from Nigella sativa against cardiovascular risk parameters in experimental hyperlipidemia Ahmad, S. and Z.H. Beg, Lipids in Health and Disease, 2013. 12.
26.    Renal function and arterial blood pressure alterations after exposure to acetaminophen with a potential role of Nigella sativa oil in adult male rats Ahmed, O.G. and N.A. Abd El-Mottaleb, Journal of Physiology and Biochemistry, 2013. 69(1): p. 1-13.
27.    Anti-tumor properties of blackseed (Nigella sativa L.) extracts Ait Mbarek, L., et al., Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.], 2007. 40(6): p. 839-47.
28.    The effect of Nigella sativa L. (black cumin seed) on intractable pediatric seizures Akhondian, J., A. Parsa, and H. Rakhshande, Medical Science Monitor, 2007. 13(12): p. CR555-CR559.
29.    A pilot study on the effects of Nigella sativa seeds aqueous extract on paediatric intractable seizures Akhondian, J.A.V., et al., Epilepsia, 2005. 46: p. 195-195.
30.    Antiulcer effects of aqueous extracts of Nigella sativa and Pongamia pinnata in rats Akhtar, A.H., et al., Fitoterapia, 1996. 67(3): p. 195-199.
31.    Neuroprotective study of Nigella sativa-loaded oral provesicular lipid formulation: in vitro and ex vivo study Akhtar, M., et al., Drug Delivery, 2014. 21(6): p. 487-494.
32.    FIELD TRIAL OF SAUSSUREA-LAPPA ROOTS AGAINST NEMATODES AND NIGELLA-SATIVA SEEDS AGAINST CESTODES IN CHILDREN Akhtar, M.S. and S. Riffat, JPMA (Journal of the Pakistan Medical Association), 1991. 41(8): p. 185-187.
33.    Nigella Sativa and Thymoquinone Suppress Cyclooxygenase-2 and Oxidative Stress in Pancreatic Tissue of Streptozotocin-Induced Diabetic Rats Al Wafai, R.J., Pancreas, 2013. 42(5): p. 841-849.
34.    Oral and intraperitoneal LD50 of thymoquinone, a.a.p.o.N.s., in mice and rats Al-Ali, Amein, et al., Journal of Ayub Medical College, Abbottabad : JAMC, 2008. 20(2): p. 25-7.
35.    Antibacterial activity of chloroform and ethanol extracts of black cumin seeds (Nigella sativa) against multi-drug resistant human pathogens under laboratory conditions Alam, M.M., et al., Journal of Medicinal Plants Research, 2010. 4(18): p. 1901-1905.
36.    Effect of Nigella sativa Supplementation to Exercise Training in a Novel Model of Physiological Cardiac Hypertrophy Al-Asoom, L.I., et al., Cardiovascular Toxicology, 2014. 14(3): p. 243-250.
37.    Effect of Allium sativa L. on pancreatic beta. cells in comparison to Nigella sativa L. in streptozotocin induced diabetic rats Albajali, A.A., et al., Journal of Medicinal Plants Research, 2011. 5(24): p. 5779-5784.
38.    Replacing bacitracin methylene disalicylate by crushed Nigella sativa seeds in broiler rations and its effects on growth, b.c.a.i.A.-B., Nafez A., S.S. El-Ghousein, and A.H. Nofal, Livestock Science, 2009. 125(2-3): p. 304-307.
39.    Anti-inflammatory Effect of Seeds and Callus of Nigella sativa L. Extracts on Mix Glial Cells with Regard to Their Thymoquinone Content Alemi, M., et al., Aaps Pharmscitech, 2013. 14(1): p. 160-167.
40.    Protective effects of Nigella sativa oil and thymoquinone against toxicity induced by the anticancer drug cyclophosphamide Alenzi, F.Q., Y.E.-S. El-Bolkiny, and M.L. Salem, British Journal of Biomedical Science, 2010. 67(1): p. 20-28.
41.    Amino acid composition and biological effects of supplementing broad bean and corn proteins with Nigella sativa (black cumin) cake protein Al-Gaby, A.M.A., Nahrung-Food, 1998. 42(5): p. 290-294.
42.    The anti-inflammatory, a.a.a.a.o.N.s.A.-G., M. S., Journal of Ethnopharmacology, 2001. 76(1): p. 45-48.
43.    Protective effect of Nigella sativa seeds against carbon tetrachloride-induced liver damage Al-Ghamdi, M.S., American Journal of Chinese Medicine, 2003. 31(5): p. 721-728.
44.    Hypoglycemic effects of the volatile oil of Nigella sativa seeds Al-Hader, A., M. Aqel, and Z. Hasan, International Journal of Pharmacognosy, 1993. 31(2): p. 96-100.
45.    Effects of two-months Nigella sativa supplementation on cardiac hemodynamics and adrenergic responsiveness Al-Hariri, M.T., et al., JPMA Journal of the Pakistan Medical Association, 2009. 59(6): p. 363-368.
46.    The effect of Nigella sativa oil on gentamicin nephrotoxicity in rats Ali, B.H., American Journal of Chinese Medicine, 2004. 32(1): p. 49-55.
47.    Pharmacological and toxicological properties of Nigella sativa Ali, B.H. and G. Blunden, Phytotherapy Research, 2003. 17(4): p. 299-305.
48.    Nigella sativa seed extract and its bioactive compound thymoquinone: the new melanogens causing hyperpigmentation in the wall lizard melanophores Ali, S.A. and K.V. Meitei, Journal of Pharmacy and Pharmacology, 2011. 63(5): p. 741-746.
49.    Nigellidine-4-O-sulfite, t.f.s.i.-t.a.f.t.s.o.N.s.A., Zulfiqar, et al., Journal of Natural Products, 2008. 71(6): p. 1111-1112.
50.    Pimarane-type diterpene analogues from Nigella sativa Ali, Z. and I.A. Khan, Planta Medica, 2008. 74(9): p. 1077-1077.
51.    TREATMENT OF NIGELLA SATIVA IN EXPERIMENTAL SEPSIS MODEL IN RATS Alici, O., et al., Pakistan Journal of Pharmaceutical Sciences, 2011. 24(2): p. 227-231.
52.    Protective and antidiabetic effects of extract from Nigella sativa on blood glucose concentrations against streptozotocin (STZ)-induced diabetic in rats: an experimental study with histopathological evaluation Alimohammadi, S., et al., Diagnostic Pathology, 2013. 8.
53.    Antidermatophyte activity of ether extract of Nigella sativa and its active principle, t.A., S. H. M., et al., Journal of Ethnopharmacology, 2005. 101(1-3): p. 116-119.
54.    Effects of Nigella sativa and Lepidium sativum on cyclosporine pharmacokinetics Al-Jenoobi, F.I., et al., BioMed research international, 2013. 2013: p. 953520-953520.
55.    Effect of Nigella sativa on blood hemostatic function in rats Al-Jishi, S.A. and B.A. Hozaifa, Journal of Ethnopharmacology, 2003. 85(1): p. 7-14.
56.    Role of Nigella sativa and a Number of its Antioxidant Constituents towards Azoxymethane-induced Genotoxic Effects and Colon Cancer in Rats Al-Johar, D., et al., Phytotherapy Research, 2008. 22(10): p. 1311-1323.
57.    Lepidium sativum but not Nigella sativa affects carbamazepine disposition in an animal model Alkharfy, K.M., et al., Drug metabolism letters, 2013. 7(1): p. 47-51.
58.    Effects of Lepidium sativum, N.s.a.T.f.-g.o.P.P.i.B.D.A., Khalid M., et al., Phytotherapy Research, 2013. 27(12): p. 1800-1804.
59.    Effects of Nigella sativa L. and Cinnamomum zeylanicum Blume oils on some physiological parameters in streptozotocin-induced diabetic rats Al-Logmani, A.S. and T.A. Zari, Boletin Latinoamericano Y Del Caribe De Plantas Medicinales Y Aromaticas, 2009. 8(2): p. 86-96.
60.    Effect of melanin extract from black cumin seeds (Nigella sativa L.) on humoral antibody response to sheep red blood to cells in albino rats Al-Mufarrej, S.I., A.M. Hassib, and M.F. Hussein, Journal of Applied Animal Research, 2006. 29(1): p. 37-41.
61.    Neuropharmacological activity of Nigella sativa L. extracts Al-Naggar, T.B., et al., Journal of Ethnopharmacology, 2003. 88(1): p. 63-68.
62.    Fatty Acid Profile, a.-T.C.a.T.A.A.o.O.E.f.N.s.S.A.-N., Ghanya, M. Ismail, and A.S. Al-Zubairi, International Journal of Pharmacology, 2009. 5(4): p. 244-250.
63.    Effect of Nigella Sativa and Allium Sativum Coadminstered with Simvastatin in Dyslipidemia Patients: A Prospective, R., Double-Blind Trial Alobaidi, Amina Hamed Ahmad, Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2014. 13(1): p. 68-74.
64.    Studies of some biochemical, n.a.a.-i.e.o.N.s.s.A.-O., Sahar Y., N.M. Ammar, and M.M. Abd El-Kader, Egyptian Journal of Pharmaceutical Sciences, 1998. 38(4-6): p. 451-469.
65.    Potential protective effect of Nigella sativa crude oils towards fatty liver in rats Al-Okbi, S.Y., et al., European Journal of Lipid Science and Technology, 2013. 115(7): p. 774-782.
66.    Effects of volatile oil constituents of Nigella sativa against carbon tetrachloride-induced hepatotoxicity in mice: evidence of antioxidant effects of i.p. adminstration of thymoquinone Al-Shabanah, O., T. El-Hadiyah, and M. Mansour, Toxicology, 2001. 164(1-3): p. 165-165.
67.    Anthelmintic activity of Nigella sativa L., s.o.g.n.o.s.A.-S., I. R. M., et al., Pakistan Journal of Nematology, 2008. 26(2): p. 207-218.
68.    Cytotoxicity of Nigella Sativa Seed Oil and Extract Against Human Lung Cancer Cell Line Al-Sheddi, E.S., et al., Asian Pacific Journal of Cancer Prevention, 2014. 15(2): p. 983-987.
69.    Hepatoprotective and Immunological Functions of Nigella sativa Seed Oil against Hypervitaminosis A in Adult Male Rats Al-Suhaimi, E.A., International Journal for Vitamin and Nutrition Research, 2012. 82(4): p. 288-297.
70.    Effects of Nigella sativa and human parathyroid hormone on bone mass and strength in diabetic rats Altan, M.F., Biological Trace Element Research, 2007. 116(3): p. 321-328.
71.    Combination therapy of Nigella sativa and human parathyroid hormone on bone mass, b.b.a.s.i.s.-i.d.r.A., Mehmet Fatih, et al., Acta Histochemica, 2007. 109(4): p. 304-314.
72.    Effect of Nigella sativa and bee honey on pulmonary, h.a.r.f.i.S.i.K.s.A., Nahid Mahmoud A. L., et al., Journal of Medicinal Plants Research, 2011. 5(31): p. 6857-6863.
73.    Pharmacological Investigation of Protective Effects of Nigella Sativa oil in Experimental Diabetic Neuropathy in Rats Ansari, M.A., et al., Indian Journal of Pharmaceutical Education and Research, 2009. 43(2): p. 166-176.
74.    ANTI MICROBIAL ACTIVITY OF ESSENTIAL OIL FIXED OIL AND UNSAPONIFIABLE MATTER OF NIGELLA-SATIVA Rathee, P.S., S.H. Mishra, and R. Kaushal, Indian Journal of Pharmaceutical Sciences, 1982. 44(1): p. 8-10.
75.    ANTIFUNGAL ACTIVITIES OF THE OILS OF NIGELLA-SATIVA SEEDS Islam, S.K.N., et al., Pakistan Journal of Pharmaceutical Sciences, 1989. 2(1): p. 25-28.
76.    ANTIMICROBIAL ACTIVITY OF BLACK CUMIN NIGELLA-SATIVA L. ESSENTIAL OIL Akgul, A., Gazi Universitesi Eczacilik Fakultesi Dergisi, 1989. 6(1): p. 63-68.
77.    ANTIMICROBIAL ACTIVITY OF VOLATILE OIL OF NIGELLA-SATIVA LINNEAUS SEEDS Toama, M.A., T.S. Elalfy, and Elfatatr.Hm, Antimicrobial Agents and Chemotherapy, 1974. 6(2): p. 225-226.
78.    ANTI-MICROBIAL AND ANTHELMINTIC ACTIVITIES OF THE ESSENTIAL OIL OF NIGELLA-SATIVA LINN Agarwal, R., M.D. Kharya, and R. Shrivastava, Indian Journal of Experimental Biology, 1979. 17(11): p. 1264-1265.
79.    Effects of the volatile oil of Nigella sativa seeds on the uterine smooth muscle of rat and guinea pig Aqel, M. and R. Shaheen, Journal of Ethnopharmacology, 1996. 52(1): p. 23-26.
80.    Effects of Nigella sativa seeds on intestinal smooth muscle Aqel, M.B., International Journal of Pharmacognosy, 1993. 31(1): p. 55-60.
81.    The relaxing effect of the volatile oil of Nigella sativa seeds on vascular smooth muscle Aqel, M.B., Dirasat Series B Pure and Applied Sciences, 1993. 19(2): p. 91-100.
82.    The calcium antagonistic effect of the volatile oil of Nigella sativa seeds Aqel, M.B., Dirasat Series B Pure and Applied Sciences, 1993. 19(1): p. 119-133.
83.    Evaluation of the Possible Epileptogenic Activity of Ciprofloxacin: The Role of Nigella sativa on Amino Acids Neurotransmitters Arafa, N.M.S., et al., Neurochemical Research, 2013. 38(1): p. 174-185.
84.    AROMA VOLATILES OF NIGELLA-SATIVA L. SEEDS Aboutabl, E.A., A.A. El-Azzouny, and F.J. Hammerschmidt. Brunke, E.-J. 1986. 49-56.
85.    A case study report of acute renal failure associated with Nigella sativa in a diabetic patient Arslan, E., et al., Journal of integrative medicine, 2013. 11(1): p. 64-6.
86.    Effect of the Volatile Oil of Nigella sativa Seeds and Its Components on Body Temperature of Mice: Elucidation of the Mechanisms of Action Ashour, M.M., et al., Natural Product Sciences, 2006. 12(1): p. 14-18.
87.    Nigella sativa Extract as a Potent Antioxidant for Petrochemical-Induced Oxidative Stress Ashraf, S.S., et al., Journal of Chromatographic Science, 2011. 49(4): p. 321-326.
88.    Assessment of Anticonvulsant Activity of Nigella Sativa Volatile Oil in Albino Rats Asmatanzeem, B.M. Parashivamurthy, and Vadhiraj, Indian Journal of Pharmacology, 2013. 45: p. S242-S242.
89.    Radioprotective effects of black seed (Nigella sativa) oil against hemopoietic damage and immunosuppression in gamma-irradiated rats Assayed, M.E., Immunopharmacology and Immunotoxicology, 2010. 32(2): p. 284-296.
90.    NIGELLIMINE - A NEW ISOQUINOLINE ALKALOID FROM THE SEEDS OF NIGELLA-SATIVA Attaurrahman, S. Malik, and K. Zaman, Journal of Natural Products, 1992. 55(5): p. 676-678.
91.    Nigellidine: A new indazole alkaloid from the seeds of Nigella sativa Atta-Ur-Rahman, S.M., et al., Tetrahedron Letters, 1995. 36(12): p. 1993-1996.
92.    Lindane-induced biochemical perturbations in rat serum and attenuation by omega-3 and Nigella sativa seed oil Attia, A.M., et al., Indian Journal of Biochemistry & Biophysics, 2011. 48(3): p. 184-190.
93.    Quantitative Determination of Chemical Constituents from Seeds of Nigella sativa L. by using HPLC-UV and Identification by LC-ESI-TOF Avula, B., et al., Planta Medica, 2009. 75(4): p. 440-441.
94.    In vitro decreases of the fibrinolytic potential of cultured human fibrosarcoma cell line, H., by Nigella sativa oil Awad, E. M., Phytomedicine, 2005. 12(1-2): p. 100-107.
95.    Cytotoxic effects of Nigella sativa oil on cultured human fibrosarcoma cell line in vitro via modulation of fibrinolytic system Awad, E.M. and B.R. Binder, Toxicology, 2001. 164(1-3): p. 91-91.
96.    In vitro induction of endothelial cell fibrinolytic alterations by Nigella sativa Awad, E.M. and B.R. Binder, Phytomedicine, 2005. 12(3): p. 194-202.
97.    The effect of Nigella sativa oil against Aspiculuris tetraptera and Hymenolepis nana in naturally infected mice Ayaz, E., et al., Saudi Medical Journal, 2007. 28(11): p. 1654-1657.
98.    Compositions from Nigella sativa Babish, J.G., L.M. Pacioretty, and J. Debenedetto. 2013, Bionexus Ltd.
99.    The in vivo antileishmanial activity of alcoholic extract from Nigella sativa seeds Bafghi, A.F., et al., African Journal of Microbiology Research, 2011. 5(12): p. 1504-1510.
100.    Anti-coccidial activity of Nigella sativa L Baghdadi, H.B. and E.M. Al-Mathal, Journal of Food Agriculture & Environment, 2011. 9(2): p. 10-17.
101.    Proapoptotic and Antimetastatic Properties of Supercritical CO2 Extract of Nigella sativa Linn. Against Breast Cancer Cells Baharetha, H.M., et al., Journal of Medicinal Food, 2013. 16(12): p. 1121-1130.
102.    DETECTION OF THE ANTIBACTERIAL EFFECT OF NIGELLA SATIVA GROUND SEEDS WITH WATER Bakathir, H.A. and N.A. Abbas, African Journal of Traditional Complementary and Alternative Medicines, 2011. 8(2): p. 159-164.
103.    Oral Nigella sativa oil ameliorates ovalbumin-induced bronchial asthma in mice Balaha, M.F., et al., International Immunopharmacology, 2012. 14(2): p. 224-231.
104.    Nigella sativa is a safe herbal product Bamosa, A., Journal of integrative medicine, 2014. 12(1): p. 66-66.
105.    Effect of Nigella sativa seeds on the glycemic control of patients with type 2 diabetes mellitus Bamosa, A.O., et al., Indian journal of physiology and pharmacology, 2010. 54(4): p. 344-54.
106.    Anxiolytic and hyperlocomotive effects of aqueous extract of Nigella sativa L. seeds in rats Bano, F., et al., Pakistan Journal of Pharmaceutical Sciences, 2014. 27(5): p. 1547-1552.
107.    Effects of Nigella sativa on outcome of hepatitis C in Egypt Barakat, E.M.F., L.M. El Wakeel, and R.S. Hagag, World Journal of Gastroenterology, 2013. 19(16): p. 2529-2536.
108.    Effect of Nigella Sativa on Carbon Tetrachloride and Paracetamol Induced hepatotoxicity: Role of Antioxidant Enzymes and Cytokines Barakat, M.K., et al., Faseb Journal, 2010. 24.
109.    The effectiveness of Nigella sativa in preventing the airway remodeling through an immune response modulation in the asthmatic mouse model Barlianto, W., et al., Allergy, 2013. 68: p. 238-238.
110.    Effect of Nigella sativa oil on liver and kidney functions of adult and senile rats Bashandy, S.A.E., Egyptian Journal of Pharmaceutical Sciences, 1996. 37(1-6): p. 313-327.
111.    A double-blind, r., placebo-control trial to evaluate the effect of Nigella sativa on palmer arsenical keratosis patients Bashar, Tahmina, M. Misbahuddin, and M.A. Hossain, Bangladesh Journal of Pharmacology, 2014. 9(1): p. 15-21.
112.    Analgesic Effect of Nigella sativa Seeds Extract on Experimentally Induced Pain in Albino Mice Bashir, M.U. and H.J. Qureshi, Jcpsp-Journal of the College of Physicians and Surgeons Pakistan, 2010. 20(7): p. 464-467.
113.    Nigella sativa AS A POTENTIAL THERAPY FOR THE TREATMENT OF LUNG INJURY CAUSED BY CECAL LIGATION AND PUNCTURE-INDUCED SEPSIS MODEL IN RATS Bayir, Y., et al., Cellular and Molecular Biology, 2012. 58: p. 1680-1687.
114.    Nigella Sativa Reduces Tissue Damage in Rat Ovaries Subjected to Torsion and Detorsion: Oxidative Stress, P.R.a.H.E.B., Yasin, et al., Gynecologic and Obstetric Investigation, 2012. 74(1): p. 41-49.
115.    Nigella sativa protects against ischaemia/reperfusion injury in rat kidneys Bayrak, O., et al., Nephrology Dialysis Transplantation, 2008. 23(7): p. 2206-2212.
116.    Antidiabetic activity of Nigella sativa seed extract in cultured pancreatic beta-cells, s.m.c., and adipocytes Benhaddou-Andaloussi, Ali, et al., Pharmaceutical Biology, 2008. 46(1-2): p. 96-104.
117.    Multiple molecular targets underlie the antidiabetic effect of Nigella sativa seed extract in skeletal muscle, a.a.l.c.B.-A., A., et al., Diabetes Obesity & Metabolism, 2010. 12(2): p. 148-157.
118.    CHEMICAL COMPOSITION AND PHYSICOCHEMICAL CHARACTERISTICS OF FIXED OILS FROM ALGERIAN Nigella sativa SEEDS Benkaci-Ali, F., et al., Chemistry of Natural Compounds, 2012. 47(6): p. 925-931.
119.    The effect of Nigella sativa Linn. seed on memory, a.a.c.i.h.h.v.B.S., Muhammad Shandaat, et al., Journal of Ethnopharmacology, 2013. 148(3): p. 780-786.
120.    Nigella sativa L. seeds modulate mood, a.a.c.i.h.a.m.B.S., Muhammad Shandaat, et al., Journal of Ethnopharmacology, 2014. 152(1): p. 156-162.
121.    Nigella sativa: Its role as an anticonvulsant in pentylenetetrazole induced seizures Biswas, D. and D. Guha, Biogenic Amines, 2007. 21(1-2): p. 66-76.
122.    The Possible Prophylactic Effect of Nigella sativa Seed Aqueous Extract on Respiratory Symptoms and Pulmonary Function Tests on Chemical War Victims: A Randomized, D.-B., Placebo-Controlled Trial Boskabady, Mohammad H. and J. Farhadi, Journal of Alternative and Complementary Medicine, 2008. 14(9): p. 1137-1144.
123.    The possible prophylactic effect of Nigella sativa seed extract in asthmatic patients Boskabady, M.H., et al., Fundamental & Clinical Pharmacology, 2007. 21(5): p. 559-566.
124.    The possible prophylactic effect of Nigella sativa seed extract in asthmatic patients (vol 21, p., 2007) Boskabady, Mohammad Hossein, et al., Fundamental & Clinical Pharmacology, 2008. 22(1): p. 105-105.
125.    The effect of Nigella sativa extract on tracheal responsiveness and lung inflammation in ovalbumin-sensitized guinea pigs Boskabady, M.H., et al., Clinics, 2011. 66(5): p. 879-887.
126.    Relaxant effects of different fractions from Nigella sativa L. on guinea pig tracheal chains and its possible mechanism(s) Boskabady, M.H., R. Keyhanmanesh, and M.A.E. Saadatloo, Indian Journal of Experimental Biology, 2008. 46(12): p. 805-810.
127.    Antiasthmatic effect of Nigella sativa in airways of asthmatic patients Boskabady, M.H., N. Mohsenpoor, and L. Takaloo, Phytomedicine, 2010. 17(10): p. 707-713.
128.    Effects of aqueous and macerated extracts from Nigella sativa on guinea pig isolated heart activity Boskabady, M.H., M.N. Shafei, and H. Parsaee, Pharmazie, 2005. 60(12): p. 943-948.
129.    Bronchodilatory and anticholinergic effects of nigella sativa on isolated guinea-pig tracheal chain Boskabady, M.H., M. Shahabi, and M. Talebi, European Respiratory Journal Supplement, 1997. 10(25): p. 53S-53S.
130.    Inhibitory effect of Nigella sativa on histamine (H-1) receptors of isolated guinea pig tracheal chains Boskabady, M.H. and N. Sheiravi, Pharmaceutical Biology, 2002. 40(8): p. 596-602.
131.    Possible mechanism(s) for relaxant effect of aqueous and macerated extracts from Nigella sativa on tracheal chains of guinea pig Boskabady, M.H., et al., BMC Pharmacology, 2004. 4: p. 3-Article No.: 3.
132.    The effect of Nigella sativa alone, a.i.c.w.d., on tracheal muscle responsiveness and lung inflammation in sulfur mustard exposed guinea pigs Boskabady, Mohammad Hossein, et al., Journal of Ethnopharmacology, 2011. 137(2): p. 1028-1034.
133.    Potential immunomodulation effect of the extract of Nigella sativa on ovalbumin sensitized guinea pigs Boskabady, M.-H., et al., Journal of Zhejiang University-Science B, 2011. 12(3): p. 201-209.
134.    Nigella sativa Oil Reduces Aluminium Chloride-Induced Oxidative Injury in Liver and Erythrocytes of Rats Bouasla, I., et al., Biological Trace Element Research, 2014. 162(1-3): p. 252-261.
135.    Phenolic composition and biological activities of Tunisian Nigella sativa L. shoots and roots Bourgou, S., et al., Comptes Rendus Biologies, 2008. 331(1): p. 48-55.
136.    Terpenoids isolated from Tunisian Nigella sativa L. essential oil with antioxidant activity and the ability to inhibit nitric oxide production Bourgou, S., et al., Flavour and Fragrance Journal, 2012. 27(1): p. 69-74.
137.    Comparative Gastroprotective Effects of Natural Honey, N.s.a.C.A.A.A.I.G.U.i.A.R.B., Mulazim Hussain, et al., Jcpsp-Journal of the College of Physicians and Surgeons Pakistan, 2011. 21(3): p. 151-156.
138.    Antioxidant activity of Nigella sativa essential oil Burits, M. and F. Bucar, Phytotherapy Research, 2000. 14(5): p. 323-328.
139.    Nigella sativa: Reduces the Risk of Various Maladies Butt, M.S. and M.T. Sultan, Critical Reviews in Food Science and Nutrition, 2010. 50(7): p. 654-665.
140.    Effect of Nigella sativa (black seed) oil on cytokine production of splenic mononuclear cells in allergen sensitized mice Buyukozturk, S., et al., Genes and Immunity, 2005. 6: p. S14-S14.
141.    Nigella sativa (black seed) oil does not affect the T-helper 1 and T-helper 2 type cytokine production from splenic mononuclear cells in allergen sensitized mice Buyukozturk, S., et al., Journal of Ethnopharmacology, 2005. 100(3): p. 295-298.
142.    Irradiation, R.a.N.s.C., M., et al., Herbal Radiomodulators: Applications in Medicine, Homeland Defence and Space, 2008: p. 47-65.
143.    In vivo radioprotective effects of Nigella sativa L oil and reduced glutathione against irradiation-induced oxidative injury and number of peripheral blood lymphocytes in rats Cemek, M., et al., Photochemistry and Photobiology, 2006. 82(6): p. 1691-1696.
144.    Antibacterial activity of Thymoquinone, a.a.p.o.N.s.a.i.p.t.p.b.b.f.C., Kamel, et al., Bmc Complementary and Alternative Medicine, 2011. 11.
145.    Therapeutic effects of Nigella sativa on chronic HAART-induced hyperinsulinemia in rats Chandra, S., et al., Canadian Journal of Physiology and Pharmacology, 2009. 87(4): p. 300-309.
146.    Anti-inflammatory effects of the nigella sativa seed extract, t., in pancreatic cancer cells Chehl, Navdeep, et al., Proceedings of the American Association for Cancer Research Annual Meeting, 2009. 50: p. 118-118.
147.    Chemical constitution of Egyptian Nigella sativa L. seeds. II. The essential oil El, D., Planta Med, 1963. 11((4)): p. 465-470.
148.    Choleretic action of Nigella sativa L. seeds oil Mahfouz, M., et al., Egypt Pharma Bull, 1962. 44((4)): p. 225-229.
149.    Therapeutic potential of the volatile oil of Nigella sativa seeds in monkey model with experimental shigellosis Chowdhury, A.K.A., et al., Phytotherapy Research, 1998. 12(5): p. 361-363.
150.    The effects of Nigella sativa on bile duct ligation induced-liver injury in rats Coban, S., et al., Cell Biochemistry and Function, 2010. 28(1): p. 83-88.
151.    The Chemopreventive Effect of Nigella Sativa on 1, -.d.-i.C.T.D., A., et al., Indian Journal of Pharmaceutical Education and Research, 2014. 48(1): p. 39-48.
152.    Effect of Nigella sativa (kalonji) on serum cholesterol of albino rats Dahri, A.H., et al., Journal of Ayub Medical College, Abbottabad : JAMC, 2005. 17(2): p. 72-4.
153.    Efficacy of Nigella sativa on serum free testosterone and metabolic disturbances in central obese male Datau, E.A., et al., Acta medica Indonesiana, 2010. 42(3): p. 130-4.
154.    Effects of Nigella sativa and vitamin E+Se in CCl4 treated rats Deger, Y., et al., Indian Veterinary Journal, 2004. 81(6): p. 647-649.
155.    Antihypertensive effect of Nigella sativa seed extract in patients with mild hypertension Dehkordi, F.R. and A.F. Kamkhah, Fundamental & Clinical Pharmacology, 2008. 22(4): p. 447-452.
156.    Effect of black cumin (Nigella sativa) on heart rate, s.h.v., and pancreatic beta-cell damage in cadmium-treated rats Demir, H., et al., Biological Trace Element Research, 2006. 110(2): p. 151-162.
157.    Protective effect of Nigella sativa oil against binge ethanol-induced oxidative stress and liver injury in rats Develi, S., et al., Chinese Journal of Natural Medicines, 2014. 12(7): p. 495-499.
158.    Effect of fatty acids of nigella sativa L. seeds oil in the prevention of the insulinoresistance and the hyperlipidemia on obese male rat Didi, A., et al., Fundamental & Clinical Pharmacology, 2013. 27: p. 27-28.
159.    Antiproliferative Properties of Methanolic Extract of Nigella sativa against the MDA-MB-231 Cancer Cell Line Dilshad, A., et al., Asian Pacific Journal of Cancer Prevention, 2012. 13(11): p. 5839-5842.
160.    Symptomatic treatment of acute tonsillopharyngitis patients with a combination of Nigella sativa and Phyllanthus niruri extract Dirjomuljono, M., et al., International Journal of Clinical Pharmacology and Therapeutics, 2008. 46(6): p. 295-306.
161.    Cellular uptake of Nigella sativa oil-PLGA microparticle by PC-12 cell line Doolaanea, A.A., et al., Journal of Microencapsulation, 2014. 31(6): p. 600-608.
162.    Nigella sativa (black cumin) seed extract alleviates symptoms of allergen-induced diarrhea in mice and decreases related immune parameters Duncker, S., et al., Allergy, 2010. 65: p. 417-417.
163.    Nigella sativa (black cumin) seed extract alleviates symptoms of allergic diarrhea in mice, i.o.r.D., Swantje C., et al., PloS one, 2012. 7(6): p. e39841-e39841.
164.    Effect of different levels of feed added black seed (Nigella sativa L.) on the performance of broiler chicks Durrani, F.R., et al., Pakistan journal of biological sciences: PJBS, 2007. 10(22): p. 4164-7.
165.    Role of Nigella sativa in ameliorating chloramphenicol induced tissue damage in rats Ebaid, H., et al., Journal of Medicinal Plants Research, 2011. 5(2): p. 280-288.
166.    Cardioprotective Effects of Nigella sativa Oil on Cyclosporine A-Induced Cardiotoxicity in Rats Ebru, U., et al., Basic & Clinical Pharmacology & Toxicology, 2008. 103(6): p. 574-580.
167.    The Chemical Composition and the Content of Volatile Oil: Potential Factors that Can Contribute to the Oxidative Stability of Nigella sativa L. Crude Oil Edris, A.E., Journal of Dietary Supplements, 2011. 8(1): p. 34-42.
168.    EFFECT OF EPHEDRINE ON MERISTEMATIC CELLS OF NIGELLA-SATIVA L Mogili, T., et al., Indian Botanical Reporter, 1986. 5(2): p. 214-217.
169.    EFFECT OF SEEDS OF KALAUNJI NIGELLA-SATIVA L. ON THE FERTILITY AND SIALIC ACID CONTENT OF THE REPRODUCTIVE ORGANS OF THE MALE RAT Agarwal, C., et al., Geobios (Jodhpur), 1990. 17(5-6): p. 269-272.
170.    Terpene Conjugates of the Nigella sativa Seed-Oil Constituent Thymoquinone with Enhanced Efficacy in Cancer Cells Effenberger, K., S. Breyer, and R. Schobert, Chemistry & Biodiversity, 2010. 7(1): p. 129-139.
171.    EFFICACY OF NIGELLA-SATIVA LINN. SEEDS AGAINST MONIEZIA INFECTION IN SHEEP Akhtar, M.S. and I. Javed, Indian Veterinary Journal, 1991. 68(8): p. 726-729.
172.    3 and only minor efficacy on spontaneous Eimeria tenella coccidiosis Ei-Sayed, Amr, T.s.o.N.s.a.a.f.a.t.m.l.-t.c.l.o.h.-a.n.a.f.o.i.f.v.w.p.t.a., et al., Archiv fuer Gefluegelkunde, 2005. 69(1): p. 27-34.
173.    Some biochemical and haematological effects of black seed (Nigella sativa) oil on Trypanosoma brucei-infected rats Ekanem, J.T. and O.K. Yusuf, African Journal of Biotechnology, 2008. 7(2): p. 153-157.
174.    Protective effect of cysteine and vitamin E, C.s.a.N.s.e.o.c.-i.t.i.r.e.D., E. S., Journal de pharmacie de Belgique, 1998. 53(2): p. 87-93; discussion 93-5.
175.    Effect of Nigella sativa fixed oil on the hormonal profile of androgens and circulating in male rats El Khasmi, M., et al., Phytotherapie (Paris), 2011. 9(6): p. 338-342.
176.    The effect of antioxidant properties of aqueous garlic extract and Nigella sativa as anti-schistosomiasis agents in mice El Shenawy, N.S., M.F.M. Soliman, and S.I. Reyad, Revista Do Instituto De Medicina Tropical De Sao Paulo, 2008. 50(1): p. 29-36.
177.    Evaluation of the in vitro effect of Nigella sativa aqueous extract on Blastocystis hominis isolates El Wakil, H.S., Journal of the Egyptian Society of Parasitology, 2007. 37(3): p. 801-813.
178.    Evaluation of the in vitro effect of Nigella sativa aqueous extract on Blastocystis hominis isolates El Wakil, S.S., Journal of the Egyptian Society of Parasitology, 2007. 37(3): p. 801-13.
179.    Gastroprotective activity of Nigella sativa oil and its constituent, t., against gastric mucosal injury induced by ischaemia/reperfusion in rats El-Abhar, H. S., D.M. Abdallah, and S. Saleh, Journal of Ethnopharmacology, 2003. 84(2-3): p. 251-258.
180.    The biochemical and morphological alterations following administration of melatonin, r.a.a.N.s.i.m.c.a.a.m.e.-A., Mohamad A. Abd, et al., International journal of experimental pathology, 2005. 86(6): p. 383-96.
181.    Cardiac inotropic and hypertrophic effects of Nigella sativa supplementation in rats El-Bahai, M.N., et al., International Journal of Cardiology, 2009. 131(3): p. E115-E117.
182.    Study on the protective role of Nigella sativa oil on steroid-induced osteoporosis in rats El-Dakhakhny, M. and S.M. Aly, British Journal of Pharmacology, 1999. 128: p. U15-U15.
183.    Effects of Nigella sativa oil on gastric secretion and ethanol induced ulcer in rats El-Dakhakhny, M., et al., Journal of Ethnopharmacology, 2000. 72(1-2): p. 299-304.
184.    Protective effect of Nigella sativa oil and clindamycin against production of tumor necrosis factor-alpha and liver injury in murine septic peritonitis El-Dakhakhny, M., et al., Naunyn-Schmiedeberg's Archives of Pharmacology, 2000. 362(4-5 Supplement): p. R17-R17.
185.    Nigella sativa oil, n.a.d.t.i.s.o.-l.p.i.p.l.f.r.E.-D., M., et al., Journal of Ethnopharmacology, 2002. 81(2): p. 161-164.
186.    The hypoglycemic effect of Nigella sativa oil is mediated by extrapancreatic actions El-Dakhakhny, M., et al., Planta Medica, 2002. 68(5): p. 465-466.
187.    Protective effect of nigella sativa oil (NSO), d.t., Quinapril and vitamin E on glycerol induced acute renal failure (Arf) in rats El-Dakhakhny, M., N.I. Mady, and T.A. Aziem, Naunyn-Schmiedebergs Archives of Pharmacology, 2003. 367: p. R71-R71.
188.    Effect of Nigella sativa L. oil on some liver function tests, p.e.a.i.h.l.p.i.r.E., M., N.I. Mady, and M.A. Halim, Naunyn-Schmiedebergs Archives of Pharmacology, 1997. 356(4): p. 235-235.
189.    Nigella sativa L. oil protects against induced hepatotoxicity and improves serum lipid profile in rats El-Dakhakhny, M., N.I. Mady, and M.A. Halim, Arzneimittel-Forschung-Drug Research, 2000. 50(9): p. 832-836.
190.    Evaluation of cytological effects of Zn2+ in relation to germination and root growth of Nigella sativa L. and Triticum aestivum L El-Ghamery, A.A., M.A. El-Kholy, and M.A. Abou El-Yousser, Mutation Research-Genetic Toxicology and Environmental Mutagenesis, 2003. 537(1): p. 29-41.
191.    Antibacterial properties of essential oils from Nigella sativa seeds, C.c.l.a.P.u.a.p.E.-K., H. H., et al., Fitoterapia, 1998. 69(1): p. 77-78.
192.    Hepatoprotective effects of Nigella sativa and bees' honey on hepatotoxicity induced by administration of sodium nitrite and sunset yellow El-Kholy, W.M., et al., Faseb Journal, 2009. 23.
193.    Nigella sativa seed extract: 1. Enhancement of sheep macrophage immune functions in vitro Elmowalid, G., A.M. Amar, and A.A.M. Ahmad, Research in Veterinary Science, 2013. 95(2): p. 437-443.
194.    Nigella Sativa L. activity on aminoacids release in mouse brain structures El-Naggar, T., et al., Planta Medica, 2007. 73(9): p. 998-999.
195.    Nigella sativa L. seed extract modulates the neurotransmitter amino acids release in cultured neurons in vitro El-Naggar, T., et al., Journal of biomedicine & biotechnology, 2010. 2010: p. 398312-398312.
196.    Nigella sativa L. Seed Extract Modulates the Neurotransmitter Amino Acids Release in Cultured Neurons In Vitro El-Naggar, T., et al., Journal of Biomedicine and Biotechnology, 2010.
197.    Thymoquinone and Nigella sativa oil protection against methionine-induced hyperhomocysteinemia in rats El-Saleh, S.C., O.A. Al-Sagair, and M.I. Al-Khalaf, International Journal of Cardiology, 2004. 93(1): p. 19-23.
198.    Effect of Nigella sativa Oil and Activated Charcoal as Antioxidant on Verrucarin J induced Hepatotoxicity in Male Rats El-Sawi, N.M. and H.M. Gashlan, Journal of Applied Animal Research, 2010. 37(2): p. 285-288.
199.    Upregulation of Chemoprotective Enzymes and Glutathione by Nigella sativa (Black Seed) and Thymoquinone in CCl4-Intoxicated Rats El-Sayed, W.M., International Journal of Toxicology, 2011. 30(6): p. 707-714.
200.    THE RESPIRATORY EFFECTS OF THE VOLATILE OIL OF THE BLACK SEED (NIGELLA-SATIVA) IN GUINEA-PIGS - ELUCIDATION OF THE MECHANISM(S) OF ACTION Eltahir, K.E.H., M.M.S. Ashour, and M.M. Alharbi, General Pharmacology, 1993. 24(5): p. 1115-1122.
201.    THE CARDIOVASCULAR ACTIONS OF THE VOLATILE OIL OF THE BLACK SEED (NIGELLA-SATIVA) IN RATS - ELUCIDATION OF THE MECHANISM OF ACTION Eltahir, K.E.H., M.M.S. Ashour, and M.M. Alharbi, General Pharmacology, 1993. 24(5): p. 1123-1131.
202.    Dietary supplementation of chloroquine with nigella sativa seed and oil extracts in the treatment of malaria induced in mice with plasmodium berghei Emeka, P.M., et al., Pharmacognosy Magazine, 2014. 10(38): p. 357-362.
203.    In Vitro Evaluation of Antibacterial Activity of Aqueous and Organic Extracts of Nigella sativa L. and Foeniculum vulgare Mill. seeds Ennadir, J., et al., Phytotherapie (Paris), 2014. 12(5): p. 302-308.
204.    Hematological studies on black cumin oil from the seeds of Nigella sativa L Enomoto, S., et al., Biological & Pharmaceutical Bulletin, 2001. 24(3): p. 307-310.
205.    Anti-inflammatuar and anti-oxidative effects of Nigella sativa L.: (18)FDG-PET imaging of inflammation Entok, E., et al., Molecular Biology Reports, 2014. 41(5): p. 2827-2834.
206.    The effects of Nigella sativa against oxidative injury in a rat model of subarachnoid hemorrhage Ersahin, M., et al., Acta Neurochirurgica, 2011. 153(2): p. 333-341.
207.    Role of black seeds (Nigella sativa) in ameliorating carbon tetrachloride induced haematotoxicity in Swiss albino mice Essawy, A.E., et al., Journal of Medicinal Plants Research, 2010. 4(19): p. 1977-1986.
208.    The Neuroprotective Effect of Curcumin and Nigella sativa Oil Against Oxidative Stress in the Pilocarpine Model of Epilepsy: A Comparison with Valproate Ezz, H.S.A., Y.A. Khadrawy, and N.A. Noor, Neurochemical Research, 2011. 36(11): p. 2195-2204.
209.    Blood pressure lowering effect of Nigella sativa L. seed oil in healthy volunteers: a randomized, d.-b., placebo-controlled clinical trial Fallah Huseini, H., et al., Phytotherapy research : PTR, 2013. 27(12): p. 1849-53.
210.    Effect of Nigella sativa (N.Sativa L.) and oxidative stress on the survival pattern of MCF-7 breast cancer cells Farah, I.O. and R.A. Begum, in Biomedical Sciences Instrumentation, Vol 39, H. Benghuzzi and M. Tucci, Editors. 2003. p. 359-364.
211.    Mechanisms of the hypoglycaemic and immunopotentiating effects of Nigella sativa L. oil in streptozotocin-induced diabetic hamsters Fararh, K.M., et al., Research in Veterinary Science, 2004. 77(2): p. 123-129.
212.    Isulinotropic properties of Nigella sativa oil in Streptozotocin plus Nicotinamide diabetic hamster Fararh, K.M., et al., Research in Veterinary Science, 2002. 73(3): p. 279-282.
213.    Effects of Nigella sativa seeds and oil on gingivitis in diabetic rats Farrag, A.R., et al., Planta Medica, 2014. 80(16): p. 1551-1551.
214.    Protective effect of Nigella sativa seeds against lead-induced hepatorenal damage in male rats Farrag, A.-R.H., et al., Pakistan journal of biological sciences: PJBS, 2007. 10(17): p. 2809-16.
215.    Effects of gamma radiation on the bacterial flora of Nigella sativa seeds and on its oil constituents Farrag, H.A., et al., Acta Pharmaceutica (Zagreb), 2000. 50(3): p. 195-207.
216.    In vivo modulation of iNOS pathway in hepatocellular carcinoma by Nigella sativa Fathy, M. and T. Nikaido, Environmental Health and Preventive Medicine, 2013. 18(5): p. 377-385.
217.    Antiatherogenic effect of Nigella sativa L. (Kalonji) seeds in rabbits with experimentally-induced hypercholesterolemia Fatima, S., et al., International Journal of Biology and Biotechnology, 2007. 4(4): p. 437-441.
218.    Biological activity of seed aqueous extract of Nigella sativa (L.) on germination and seedling growth of Vigna radiata (L.) Fawzia, et al., Pakistan journal of biological sciences: PJBS, 2007. 10(23): p. 4319-22.
219.    INVITRO ANTIBACTERIAL ACTIVITY OF THE VOLATILE OIL OF NIGELLA-SATIVA SEEDS AGAINST MULTIPLE DRUG-RESISTANT ISOLATES OF SHIGELLA SPP AND ISOLATES OF VIBRIO-CHOLERAE AND ESCHERICHIA-COLI Ferdous, A.J., et al., Phytotherapy Research, 1992. 6(3): p. 137-140.
220.    Nephroprotective activity of Nigella sativa seeds against cisplatin induced nephrotoxicity in mice Feroz, S., et al., Indian Journal of Natural Products, 2008. 24(1): p. 13-16.
221.    Biosynthesis of Controllable Size and Shape Gold Nanoparticles by Black Seed (Nigella Sativa) Extract Fragoon, A., et al., Journal of Nanoscience and Nanotechnology, 2012. 12(3): p. 2337-2345.
222.    GALACTAGOGUE ACTION OF NIGELLA-SATIVA-D Agrawala, I.P., M.V.S. Achar, and B.P. Tamankar, Indian Journal of Medical Sciences, 1971. 25(8): p. 535-537.
223.    The medicinal potential of black seed (Nigella sativa) and its components Gali-Muhtasib, H., N. El-Najjar, and R. Schneider-Stock, Lead Molecules from Natural Products: Discovery and New Trends, 2006. 2: p. 133-153.
224.    Bullous drug eruption with Nigella sativa oil Gelot, P., et al., Annales De Dermatologie Et De Venereologie, 2012. 139(4): p. 287-291.
225.    GC-MS Analysis of Nigella sativa Seeds and Antimicrobial Activity of its Volatile oil Gerige, S.J., et al., Brazilian Archives of Biology and Technology, 2009. 52(5): p. 1189-1192.
226.    Yield and water use efficiency of (Nigella sativa L.) under different irrigation treatments in a semi arid region in the West of Iran Ghamarnia, H., H. Khosravy, and S. Sepehri, Journal of Medicinal Plants Research, 2010. 4(16): p. 1612-1616.
227.    An investigation of the analgesic and anti-inflammatory effects of Nigella sativa seed polyphenols Ghannadi, A., V. Hajhashemi, and H. Jafarabadi, Journal of Medicinal Food, 2005. 8(4): p. 488-493.
228.    The cultivated nigella: Nigella sativa L. (Ranunculaceae) Ghedira, K., Phytotherapie (Paris), 2006. 4(5): p. 220-226.
229.    Nigella cultivated oil, N.s.L.R.G., K. and R. Le Jeune, Phytotherapie (Paris), 2010. 8(2): p. 124-128.
230.    Effectiveness of Nigella sativa Oil in the Management of Rheumatoid Arthritis Patients: A Placebo Controlled Study Gheita, T.A. and S.A. Kenawy, Phytotherapy Research, 2012. 26(8): p. 1246-1248.
231.    Efficacy of Nigella sativa seeds on fertility of male diabetic rats Ghlissi, Z., et al., Fundamental & Clinical Pharmacology, 2011. 25: p. 69-69.
232.    Effect of Nigella sativa seeds on reproductive system of male diabetic rats Ghlissi, Z., et al., African Journal of Pharmacy and Pharmacology, 2012. 6(20): p. 1444-1450.
233.    A simple and a sensitive high-performance liquid chromatographic method of analysis for determination of quinones and related compounds in the oil of Nigella sativa seed Ghosheh, O.A., A.A. Houdi, and P.A. Crooks, Pharmaceutical Research (New York), 1997. 14(11 SUPPL.): p. S378-S378.
234.    High performance liquid chromatographic analysis of the pharmacologically active quinones and related compounds in the oil of the black seed (Nigella sativa L.) Ghosheh, O.A., A.A. Houdi, and P.A. Crooks, Journal of Pharmaceutical and Biomedical Analysis, 1999. 19(5): p. 757-762.
235.    Bronchodilator, s.a.c.a.a.o.N.s.s.K.A.t.h.p.w.m.m.u.G., A. H., et al., JPMA (Journal of the Pakistan Medical Association), 2001. 51(3): p. 115-120.
236.    Suppression of penicillin-induced epileptiform activity by Nigella sativa: Possible mediation by neurotransmitters Guha, D., D. Biswas, and S. Purkayastha, Biogenic Amines, 2005. 19(4-6): p. 309-321.
237.    The effect of dietary black cumin seeds (Nigella sativa L.) on the performance of broilers Guler, T., et al., Asian-Australasian Journal of Animal Sciences, 2006. 19(3): p. 425-430.
238.    Serum trace elements status of rabbits supplemented with Nigella sativa, v.C.a.E., and selenium against damage by N-methyl-N '-nitro-N-nitrosoguanidine Gunduz, H., et al., Biological Trace Element Research, 2002. 89(1): p. 65-73.
239.    The Effect of Black Seed (Nigella sativa) Extract on FOXO3 Expression in HepG2 Cells Haas, M.J., et al., Phytotherapy Research, 2014. 28(6): p. 873-879.
240.    Induction of apolipoprotein A-I gene expression by black seed (Nigella sativa) extracts Haas, M.J., et al., Pharmaceutical Biology, 2014. 52(9): p. 1119-1127.
241.    High-Performance Liquid Chromatography Quantification of Principal Antioxidants in Black seed (Nigella sativa L.) Phytopharmaceuticals Hadad, G.M., et al., Journal of Aoac International, 2012. 95(4): p. 1043-1047.
242.    Hadiyah, E.o.N.s.S.C.f.T.i.v.T.i.M.T.M.E., et al., Natural Product Sciences, 2003. 9(1): p. 22-27.
243.    Effect of Alcoholic Extract of Nigella Sativa on Cisplatin-induced Toxicity in Rat Hadjzadeh, M.-A.-R., et al., Iranian Journal of Kidney Diseases, 2012. 6(2): p. 99-104.
244.    Ethanolic extract of nigella sativa L seeds on ethylene glycol-induced kidney calculi in rats Hadjzadeh, M.-A.-R., et al., Urology journal, 2007. 4(2): p. 86-90.
245.    The preventive effect of N-butanol fraction of Nigella sativa on ethylene glycol-induced kidney calculi in rats Hadjzadeh, M.-A.-R., et al., Pharmacognosy Magazine, 2011. 7(28): p. 338-343.
246.    Effects of Nigella sativa extracts on antibody response of rats vaccinated with Brucella vaccine (Rev-1) Hailat, N., et al., Pharmaceutical Biology, 1998. 36(3): p. 217-221.
247.    EFFECT OF NIGELLA-SATIVA VOLATILE OIL ON JURKAT T-CELL LEUKEMIA POLYPEPTIDES Hailat, N., et al., International Journal of Pharmacognosy, 1995. 33(1): p. 16-20.
248.    In vitro anti-yeast effect of Nigella sativa seed quinones Halamova, K., et al., Planta Medica, 2009. 75(9): p. 947-947.
249.    Effects of Nigella sativa Oil and Thymoquinone on Oxidative Stress and Neuropathy in Streptozotocin-Induced Diabetic Rats Hamdy, N.M. and R.A. Taha, Pharmacology, 2009. 84(3): p. 127-134.
250.    STUDIES ON THE ANTIMICROBIAL ACTIVITY OF NIGELLA-SATIVA SEED (BLACK CUMIN) Hanafy, M.S.M. and M.E. Hatem, Journal of Ethnopharmacology, 1991. 34(2-3): p. 275-278.
251.    Anti bacterial activity of Nigella sativa against clinical isolates of methicillin resistant Staphylococcus aureus Hannan, A., et al., Journal of Ayub Medical College, Abbottabad : JAMC, 2008. 20(3): p. 72-4.
252.    NIGELLA-SATIVA - EFFECT ON HUMAN-LYMPHOCYTES AND POLYMORPHONUCLEAR LEUKOCYTE PHAGOCYTIC-ACTIVITY Haq, A., et al., Immunopharmacology, 1995. 30(2): p. 147-155.
253.    Immunomodulatory effect of Nigella sativa proteins fractionated by ion exchange chromatography Haq, A., et al., International Journal of Immunopharmacology, 1999. 21(4): p. 283-295.
254.    Thymoquinone, t.N.s.B.C., Prevents Circulatory Oxidative Stress Caused by 1,2-Dimethylhydrazine in Erythrocyte during Colon Postinitiation Carcinogenesis Harzallah, Hanene Jrah, et al., Oxidative Medicine and Cellular Longevity, 2012.
255.    Chemical composition, a.p.a.c.b.a.c.a.o.T.N.s.e.o.a.t.H., Hanene Jrah, et al., Food Chemistry, 2011. 129(4): p. 1469-1474.
256.    Chemical composition, a.a.a.p.o.T.N.s.f.o.H., Hanene Jrah, et al., African Journal of Microbiology Research, 2012. 6(22): p. 4675-4679.
257.    Study of Nigella Sativa For Hepatoprotective Activity in Rats Hasan, M.N., et al., Indian Journal of Pharmacology, 2013. 45: p. S178-S178.
258.    Methanolic Extract of Nigella sativa Seed Inhibits SiHa Human Cervical Cancer Cell Proliferation Through Apoptosis Hasan, T.N., et al., Natural Product Communications, 2013. 8(2): p. 213-216.
259.    A study of the effect of Nigella sativa (Black seeds) in isoniazid (INH)-induced hepatotoxicity in rabbits Hassan, A.S., J.H. Ahmed, and S.S. Al-Haroon, Indian Journal of Pharmacology, 2012. 44(6): p. 678-682.
260.    Antineoplastic Effects of Bee Honey and Nigella sativa on Hepatocellular Carcinoma Cells Hassan, M.I., et al., Integrative Cancer Therapies, 2012. 11(4): p. 354-363.
261.    Neuroprotective effects of Nigella sativa extract on cell death in hippocampal neurons following experimental global cerebral ischemia-reperfusion injury in rats Hobbenaghi, R., et al., Journal of the Neurological Sciences, 2014. 337(1-2): p. 74-79.
262.    The protective effect of Nigella sativa on lung injury of sulfur mustard-exposed guinea pigs Hossein, B.M., V. Nasim, and A. Sediqa, Experimental Lung Research, 2008. 34(4): p. 183-194.
263.    Anticonvulsant effects of thymoquinone, t.m.c.o.N.s.s., in mice Hosseinzadeh, H. and S. Parvardeh, Phytomedicine, 2004. 11(1): p. 56-64.
264.    Effect of thymoquinone and Nigella sativa seeds oil on lipid peroxidation level during global cerebral ischemia-reperfusion injury in rat hippocampus Hosseinzadeh, H., et al., Phytomedicine, 2007. 14(9): p. 621-627.
265.    Intracerebroventricular administration of thymoquinone, t.m.c.o.N.s.s., suppresses epileptic seizures in rats Hosseinzadeh, H., et al., Medical Science Monitor, 2005. 11(4): p. BR106-BR110.
266.    Effect of aqueous and ethanolic extracts of Nigella sativa seeds on milk production in rats Hosseinzadeh, H., et al., Journal of acupuncture and meridian studies, 2013. 6(1): p. 18-23.
267.    Effect of thymoquinone, a.c.o.N.s.L., on ischemia-reperfusion in rat skeletal muscle Hosseinzadeh, Hossein, S. Taiari, and M. Nassiri-Asl, Naunyn-Schmiedebergs Archives of Pharmacology, 2012. 385(5): p. 503-508.
268.    Inhibitory effect of Nigella sativa oil on eicosanoid synthesis Houghton, P.J., et al., Journal of Pharmacy and Pharmacology, 1994. 46(SUPPL. 2): p. 1067-1067.
269.    FIXED OIL OF NIGELLA-SATIVA AND DERIVED THYMOQUINONE INHIBIT EICOSANOID GENERATION IN LEUKOCYTES AND MEMBRANE LIPID-PEROXIDATION Houghton, P.J., et al., Planta Medica, 1995. 61(1): p. 33-36.
270.    Blood Pressure Lowering Effect of Nigella sativa L. Seed Oil in Healthy Volunteers: A Randomized, D.-B., Placebo-controlled Clinical Trial Huseini, H. Fallah, et al., Phytotherapy Research, 2013. 27(12): p. 1849-1853.
271.    The effect of fixed oil and water extracts of Nigella sativa on sickle cells: an in vitro study Ibraheem, N.K., J.H. Ahmed, and M.K. Hassan, Singapore Medical Journal, 2010. 51(3): p. 230-234.
272.    Protection by Nigella sativa against carbon tetrachloride-induced downregulation of hepatic cytochrome P450 isozymes in rats Ibrahim, Z.S., et al., Japanese Journal of Veterinary Research, 2008. 56(3): p. 119-128.
273.    Apoptotic Activities of Thymoquinone, a.A.I.o.B.S.N.s., in Cervical Cancer Cell Lines Ichwan, Solachuddin J. A., et al., Chinese Journal of Physiology, 2014. 57(5): p. 249-255.
274.    Antiepileptogenic and antioxidant effects of Nigella sativa oil against pentylenetetrazol-induced kindling in mice Ilhan, A., et al., Neuropharmacology, 2005. 49(4): p. 456-464.
275.    Induced chromosomal aberrations in somatic cells of Nigella sativa L. by mitomycin C Kumar, P. and J. Nizam, Zentralblatt fur Bakteriologie, Parasitenkunde, Infektionskrankheiten und Hygiene. Zweite naturwissenschaftliche Abteilung: Mikrobiologie der Landwirtschaft der Technologie und des Umweltschutzes, 1978. 133(6): p. 537-42.
276.    INHIBITORY EFFECTS OF NIGELLA-SATIVA AND SAFFRON (CROCUS-SATIVUS) ON CHEMICAL CARCINOGENESIS IN MICE Salomi, M.J., S.C. Nair, and K.R. Panikkar, Nutrition and Cancer-an International Journal, 1991. 16(1): p. 67-72.
277.    INVITRO ANTIBACTERIAL SCREENING OF THE OILS OF NIGELLA-SATIVA SEEDS Hasan, C.M., M. Ahsan, and S.N. Islam, Bangladesh Journal of Botany, 1989. 18(2): p. 171-174.
278.    Protective Effects of Black Cumin (Nigella sativa) Oil on TNBS-Induced Experimental Colitis in Rats Isik, F., et al., Digestive Diseases and Sciences, 2011. 56(3): p. 721-730.
279.    Galangal (Alpinia galanga Willed.) and black seeds (Nigella sativa Linn.) and sexual stimulation in male mice Islam, M.W., et al., Journal of Pharmacy and Pharmacology, 2000. 52(Supplement): p. 278-278.
280.    Immunosuppressive and cytotoxic properties of Nigella sativa Islam, S.K.N., et al., Phytotherapy Research, 2004. 18(5): p. 395-398.
281.    Nigella sativa thymoquinone-rich fraction greatly improves plasma antioxidant capacity and expression of antioxidant genes in hypercholesterolemic rats Ismail, M., G. Al-Naqeep, and K.W. Chan, Free Radical Biology and Medicine, 2010. 48(5): p. 664-672.
282.    Isolation and structure assignment of an antimicrobial principle from the volatile oil of Nigella sativa L. seeds El-Fatatry, H.M., Die Pharmazie, 1975. 30(2): p. 109-11.
283.    ISOLATION AND STRUCTURE ASSIGNMENT OF AN ANTIMICROBIAL PRINCIPLE FROM VOLATILE OIL OF NIGELLA-SATIVA-L SEEDS Elalfy, T.S., H.M. Elfatatry, and M.A. Toama, Pharmazie, 1975. 30(2): p. 109-111.
284.    ISOLATION AND STRUCTURE DETERMINATION OF NIGELLICINE, A.N.A.F.T.S.O.N.-S.A., et al., Tetrahedron Letters, 1985. 26(23): p. 2759-2762.
285.    Effect of nigella sativa oil on hepatotoxicity induced by antitubercular drugs in albino rats Jadhav, R.R., et al., Indian Journal of Pharmacology, 2008. 40: p. 200-201.
286.    Histopathological investigation of neuroprotective effects of Nigella sativa on motor neurons anterior horn spinal cord after sciatic nerve crush in rats Javanbakht, J., et al., Pathologie Biologie, 2013. 61(6): p. 250-253.
287.    Effects of Nigella (Nigella sativa L.) Seed Extract on Human Neutrophil Elastase Activity Kacem, R., Nuts and Seeds in Health and Disease Prevention, 2011: p. 823-829.
288.    Effects of essential oil extracted from Nigella sativa (L.) seeds and its main components on human neutrophil elastase activity Kacem, R. and Z. Meraihi, Yakugaku Zasshi-Journal of the Pharmaceutical Society of Japan, 2006. 126(4): p. 301-305.
289.    The effect of essential oil extracted from Nigella sativa (L.) seeds on human neutrophil functions Kacem, R. and Z. Meraihi, Natural Product Research, 2009. 23(13): p. 1168-1175.
290.    Biochemical effects of Nigella sativa L seeds in diabetic rats Kaleem, M., et al., Indian Journal of Experimental Biology, 2006. 44(9): p. 745-748.
291.    Effect of Nigella sativa (black seed) on subjective feeling in patients with allergic diseases Kalus, U., et al., Phytotherapy Research, 2003. 17(10): p. 1209-1214.
292.    Polyunsaturated fatty acid fractions of Nigella sativa L. seeds Kandil, O. 2010, Biopharm Research and Development Corporation Limited.
293.    EXTRACTS AND FRACTIONS OF NIGELLA-SATIVA (N-SATIVA) EXHIBIT ANTIMICROBIAL AND IMMUNOLOGICAL ACTIVITIES Kandil, O., et al., Faseb Journal, 1994. 8(5): p. A951-A951.
294.    Protective effects of Nigella sativa on the neuronal injury in frontal cortex and brain stem after chronic toluene exposure Kanter, M., Neurochemical Research, 2008. 33(11): p. 2241-2249.
295.    Nigella sativa and derived thymoquinone prevents hippocampal neurodegeneration after chronic toluene exposure in rats Kanter, M., Neurochemical Research, 2008. 33(3): p. 579-588.
296.    Effects of Nigella sativa and its major constituent, t.o.s.n.i.e.d.n.K., Mehmet, Neurochemical Research, 2008. 33(1): p. 87-96.
297.    Effects of Nigella sativa seed extract on ameliorating lung tissue damage in rats after experimental pulmonary aspirations Kanter, M., Acta Histochemica, 2009. 111(5): p. 393-403.
298.    Protective effects of the volatile oil of Nigella sativa seeds on beta-cell damage in streptozotocin-induced diabetic rats: a light and electron microscopic study Kanter, M., M. Akpolat, and C. Aktas, Journal of Molecular Histology, 2009. 40(5-6): p. 379-385.
299.    Hepatoprotective effects of Nigella sativa L and Urtica dioica L on lipid peroxidation, a.e.s.a.l.e.i.c.t.-t.r.K., Mehmet, O. Coskun, and M. Budancamanak, World Journal of Gastroenterology, 2005. 11(42): p. 6684-6688.
300.    Effect of black cumin (Nigella sativa) on cadmium-induced oxidative stress in the blood of rats Kanter, M., O. Coskun, and A. Gurel, Biological Trace Element Research, 2005. 107(3): p. 277-287.
301.    Neuroprotective effects of Nigella sativa on experimental spinal cord injury in rats Kanter, M., et al., Human & Experimental Toxicology, 2006. 25(3): p. 127-133.
302.    Effects of Nigella sativa on oxidative stress and beta-cell damage in streptozotocin-induced diabetic rats Kanter, M., et al., Anatomical Record Part a-Discoveries in Molecular Cellular and Evolutionary Biology, 2004. 279A(1): p. 685-691.
303.    Effects of Nigella sativa and its major constituent, t.o.e.i.g.m.d.K., M., O. Coskun, and H. Uysal, Febs Journal, 2006. 273: p. 288-289.
304.    The antioxidative and antihistaminic effect of Nigella sativa and its major constituent, t.o.e.-i.g.m.d.K., M., O. Coskun, and H. Uysal, Archives of Toxicology, 2006. 80(4): p. 217-224.
305.    Gastroprotective activity of Nigella sativa L oil and its constituent, t.a.a.a.-i.g.m.i.i.r.K., Mehmet, et al., World Journal of Gastroenterology, 2005. 11(42): p. 6662-6666.
306.    Effects of Nigella sativa L. and Urtica dioica L. on lipid peroxidation, a.e.s.a.s.l.e.i.C.-t.r.K., M., et al., Journal of Veterinary Medicine Series a-Physiology Pathology Clinical Medicine, 2003. 50(5): p. 264-268.
307.    Effects of Nigella sativa L. and Urtica dioica L. on lipid peroxidation, a.e.s.a.s.l.e.i.C.-t.r.v., pg 264, 2003) Kanter, M., et al., Journal of Veterinary Medicine Series a-Physiology Pathology Clinical Medicine, 2003. 50(7): p. 383-383.
308.    Partial regeneration/proliferation of the beta-cells in the islets of langerhans by Nigella sativa L. in Streptozotocin-induced diabetic rats Kanter, M., et al., Tohoku Journal of Experimental Medicine, 2003. 201(4): p. 213-219.
309.    Emerging clinical and therapeutic applications of Nigella sativa in gastroenterology Kapoor, S., World Journal of Gastroenterology, 2009. 15(17): p. 2170-2171.
310.    Protective effects of aqueous and ethanolic extracts of Nigella sativa L. and Portulaca oleracea L. on free radical induced hemolysis of RBCs Karimi, G., et al., Daru-Journal of Pharmaceutical Sciences, 2011. 19(4): p. 295-300.
311.    Anti-oxidant activity of dried seeds of Trigonella foenumm (fenugreek), N.s.b.c.a.L.l.l.a.d.r.f.o.T.c.a.K., et al., Indian Journal of Pharmacology, 2008. 40: p. 223-223.
312.    Post-Coital Contraceptive Efficacy Of The Seeds Of Nigella sativa In Rats Keshri, G., et al., Indian Journal of Physiology and Pharmacology, 1995. 39(1): p. 59-62.
313.    The Main Relaxant Constituents of Nigella Sativa Methanolic Fraction on Guinea Pig Tracheal Chains Keyhanmanesh, R., et al., Iranian Journal of Allergy Asthma and Immunology, 2013. 12(2): p. 136-143.
314.    The Relaxant Effects of Different Methanolic Fractions of Nigella sativa on Guinea Pig Tracheal Chains Keyhanmanesh, R., et al., Iranian Journal of Basic Medical Sciences, 2013. 16(2): p. 123-128.
315.    The Effect of Thymoquinone, t.M.C.o.N.s.o.T.R.a.W.B.C.C.i.L.L.o.S.G.P.K., Rana, et al., Planta Medica, 2010. 76(3): p. 218-222.
316.    THE EFFECT OF NIGELLA SATIVA ON TRACHEAL RESPONSIVENESS OF OVALBUMIN SENSITIZED GUINEA PIGS Keyhanmanesh, R., et al., Journal of Physiological Sciences, 2009. 59: p. 224-224.
317.    Antimicrobial activity analysis of extracts of Acacia modesta, A.a., Nigella sativa and Saussurea lappa against Gram positive and Gram negative microorganisms Khalid, Anwar, et al., African Journal of Biotechnology, 2011. 10(22): p. 4574-4580.
318.    Clinicopathological and immunological studies on Nigella Sativa oil in case of experimental STZ-induced diabetes mellitus in hamster Khalid, F. and T. Takewaki, Japanese Journal of Pharmacology, 2001. 85(Supplement 1): p. 123P-123P.
319.    A comparative study on the effect of some foliar fertilizers on the growth, y.o.S.a.a.N.s.p.K., M. Y., M.S. Hussein, and S.E. El-Sherbeny, Egyptian Journal of Horticulture, 2001. 28(3): p. 371-385.
320.    Chemical composition and medicinal properties of Nigella sativa Linn Khan, M.A., Inflammopharmacology, 1999. 7(1): p. 15-35.
321.    ANTICANCER ACTIVITIES OF NIGELLA SATIVA (BLACK CUMIN) Khan, M.A., et al., African Journal of Traditional Complementary and Alternative Medicines, 2011. 8(5): p. 226-232.
322.    The in vivo antifungal activity of the aqueous extract from Nigella sativa seeds Khan, M.A.U., et al., Phytotherapy Research, 2003. 17(2): p. 183-186.
323.    Nigella sativa (black cumin) ameliorates potassium bromate-induced early events of carcinogenesis: diminution of oxidative stress Khan, N., S. Sharma, and S. Sultana, Human & Experimental Toxicology, 2003. 22(4): p. 193-203.
324.    Inhibition of two stage renal carcinogenesis, o.d.a.h.r.b.N.s.K., N. and S. Sultana, European Journal of Cancer Prevention, 2005. 14(2): p. 159-168.
325.    Effects of black cumin seed (Nigella sativa L.) on performance and immune system in newly evolved crossbred laying hens Khan, S.H., et al., Veterinary Quarterly, 2013. 33(1): p. 15-21.
326.    Effects of the crude and the n-hexane extract of Nigella sativa Linn. (kalajira) upon diabetic rats Khanam, M. and Z.F. Dewan, Bangladesh Journal of Pharmacology, 2009. 4(1): p. 17-20.
327.    CNS and analgesic studies on Nigella sativa Khanna, T., F.A. Zaidi, and P.C. Dandiya, Fitoterapia, 1993. 64(5): p. 407-410.
328.    Inhibition of Aflatoxin Production and Growth of Aspergillus parasiticus by Cuminum cyminum, Z.c., and Nigella sativa Essential Oils Khosravi, Ali Reza, H. Shokri, and M. Minooeianhaghighi, Foodborne Pathogens and Disease, 2011. 8(12): p. 1275-1280.
329.    The effect of dietary supplementation of Nigella sativa L. on serum lipid profile in rats Kocyigit, Y., Y. Atamer, and E. Uysal, Saudi Medical Journal, 2009. 30(7): p. 893-896.
330.    Effect of nigella (Nigella sativa L.) seeds on hematological parameters in rats Kocyigit, Y., et al., Saudi Medical Journal, 2009. 30(9): p. 1233-1235.
331.    Comparison of Chemical Composition and Antibacterial Activity of Nigella sativa Seed Essential Oils Obtained by Different Extraction Methods Kokoska, L., et al., Journal of Food Protection, 2008. 71(12): p. 2475-2480.
332.    Antibacterial activity of Nigella sativa seed essential oil and effect of different extraction methods on content of its active principle, t.K., L., et al., Planta Medica, 2006. 72(11): p. 1008-1008.
333.    Effects of Nigella sativa L. seed oil on abnormal semen quality in infertile men: A randomized, d.-b., placebo-controlled clinical trial Kolahdooz, M., et al., Phytomedicine, 2014. 21(6): p. 901-905.
334.    Prophylactic effect of green tea and Nigella sativa extracts against fenitrothion-induced toxicity in rat parotid gland Korany, N.S. and B.A. Ezzat, Archives of Oral Biology, 2011. 56(11): p. 1339-1346.
335.    Effect of unsaturated fatty acid ingredient of Nigella sativa (Black Seed) on human breast cancer cells Kourosh, H.G., et al., Clinical Biochemistry, 2011. 44(13): p. S18-S18.
336.    Extraction, i.a.c.o.a.p., alpha-hederin, from the seeds of Nigella sativa Kumara, S. S. M. and B.T.K. Huat, Planta Medica, 2001. 67(1): p. 29-32.
337.    Nigella sativa L. oil ameliorates methotrexate-induced intestinal toxicity through antioxidant activity Labib, R., O. Badary, and H. Hafez, Ejc Supplements, 2009. 7(2): p. 106-106.
338.    Efficacy of Nigella sativa in alleviating benzo a pyrene-induced immunotoxicity in broilers Latif, I.K., et al., Histology and Histopathology, 2011. 26(6): p. 699-709.
339.    A randomized control trial on the effect of black seeds (Nigella sativa) on climacteric symptoms and quality of life of perimenopausal women in Rawang, S., Malaysia Latiff, Latiffah A., et al., Clinical Biochemistry, 2011. 44(13): p. S20-S21.
340.    The petroleum ether extract of Nigella sativa exerts lipid-lowering and insulin-sensitizing actions in the rat Le, P.M., et al., Journal of Ethnopharmacology, 2004. 94(2-3): p. 251-259.
341.    A squalene epoxidase from Nigella sativa participates in saponin biosynthesis and mediates terbinafine resistance in yeast Lipinski, M., et al., Central European Journal of Biology, 2009. 4(2): p. 163-169.
342.    Characterization of secondary volatile profiles in Nigella sativa seeds from two different origins using accelerated solvent extraction and gas chromatography-mass spectrometry Liu, X., et al., Biomedical Chromatography, 2012. 26(10): p. 1157-1162.
343.    Various Extraction and Analytical Techniques for Isolation and Identification of Secondary Metabolites from Nigella sativa Seeds Liu, X., A.M. Abd El-Aty, and J.H. Shim, Mini-Reviews in Medicinal Chemistry, 2011. 11(11): p. 947-955.
344.    Isolation of volatiles from Nigella sativa seeds using microwave-assisted extraction: effect of whole extracts on canine and murine CYP1A Liu, X., et al., Biomedical Chromatography, 2013. 27(7): p. 938-945.
345.    Thymoquinone, a.p.t.a.o.N.s., binds to site I of human serum albumin Lupidi, G., et al., Phytomedicine, 2010. 17(10): p. 714-720.
346.    Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E2P conformation of the Na, K.-A.F.a.d.r.c.g.i.w.t.p.M. and S.B. Christensen, Biochimica Et Biophysica Acta-Biomembranes, 2011. 1808(10): p. 2413-2420.
347.    The in vitro effect of aqueous extract of Nigella sativa seeds on nitric oxide production Mahmood, M.S., et al., Phytotherapy Research, 2003. 17(8): p. 921-924.
348.    The effect of Nigella sativa oil against the liver damage induced by Schistosoma mansoni infection in mice Mahmoud, M.R., H.S. El-Abhar, and S. Saleh, Journal of Ethnopharmacology, 2002. 79(1): p. 1-11.
349.    Hormetic/Cytotoxic Effects of Nigella sativa Seed Alcoholic and Aqueous Extracts on MCF-7 Breast Cancer Cells Alone or in Combination with Doxorubicin Mahmoud, S.S. and V.P. Torchilin, Cell Biochemistry and Biophysics, 2013. 66(3): p. 451-460.
350.    Nigella sativa modulates splenocyte proliferation, T.T.c.p., macrophage function and NK anti-tumor activity Majdalawieh, Amin F., R. Hmaidan, and R.I. Carr, Journal of Ethnopharmacology, 2010. 131(2): p. 268-275.
351.    Effects of nigella sativa oil on haloperidol induced deficit in rat model Malik, T., et al., Society for Neuroscience Abstract Viewer and Itinerary Planner, 2010. 40.
352.    Nigella sativa Oil Controls Astrogliosis and Reduces Haloperidol-Induced Deficit in Rats Malik, T., et al., Annals of Neurology, 2011. 70: p. S20-S21.
353.    Effects of Nigella sativa oil on haloperidol induced movement deficits in a rat model Malik, T., et al., European Journal of Neurology, 2012. 19: p. 335-335.
354.    Inhibition of haloperidol-induced striatal astrogliosis, p.a.t.v.c.m.b.c.o.N.s.-o.i.r.M., T., S.H. Hasan, and D.J. Haleem, Society for Neuroscience Abstract Viewer and Itinerary Planner, 2013. 43.
355.    Effects of volatile oil constituents of Nigella sativa on carbon tetrachloride-induced hepatotoxicity in mice: Evidence for antioxidant effects of thymoquinone Mansour, M.A., et al., Research Communications in Molecular Pathology and Pharmacology, 2001. 110(3-4): p. 239-251.
356.    Sensibility of male rats fertility against olive oil, N.s.o.a.p.e.M., Sherif W., et al., Asian Pacific Journal of Tropical Biomedicine, 2013. 3(7): p. 563-568.
357.    Morphological, m.a.c.c.b.N.s.L.c.b.c.a.N.d.L.c.M., Delphine, et al., Journal of Food Agriculture & Environment, 2013. 11(1).
358.    In vitro inhibitory effects of thymol and quinones of Nigella sativa seeds on cyclooxygenase-1-and-2-catalyzed prostaglandin E-2 biosyntheses Marsik, P., et al., Planta Medica, 2005. 71(8): p. 739-742.
359.    Carbohydrates of Nigella sativa and N-damascena Mashirova, S.Y., T.V. Orlovskaya, and R.K. Rakhmanberdyeva, Chemistry of Natural Compounds, 2012. 48(3): p. 460-461.
360.    Analysis of cadmium and lead in mice organs Massadeh, A.M., et al., Biological Trace Element Research, 2007. 115(2): p. 157-167.
361.    Primary human monocyte differentiation regulated by Nigella sativa pressed oil Mat, M.C., A.S. Mohamed, and S.S. Hamid, Lipids in Health and Disease, 2011. 10.
362.    "Blockade of Nitric Oxide Overproduction and Oxidative Stress by Nigella Sativa Oil Attenuates Morphine-Induced Tolerance" by Abdel-Zaher et al Mauro, D. and L. Procopio, Neurochemical Research, 2011. 36(5): p. 924-925.
363.    Anti-tumor properties of blackseed (Nigella sativa L.) extracts Mbarek, L.A., et al., Brazilian Journal of Medical and Biological Research, 2007. 40(6): p. 839-847.
364.    Nigella sativa inhibits intestinal glucose absorption and improves glucose tolerance in rats Meddah, B., et al., Journal of Ethnopharmacology, 2009. 121(3): p. 419-424.
365.    Anti-angiogenic activity of nigella sativa plant extract in cancer therapy Medenica, R., et al., Proceedings of the American Association for Cancer Research Annual Meeting, 1997. 38(0): p. 205-205.
366.    Anti-angiogenic activity of Nigella sativa plant extract in cancer therapy Medenica, R., et al., International Journal of Oncology, 1997. 11(SUPPL.): p. 912-912.
367.    Inhibitory effect of Nigella sativa on chemical carcinogenesis in mice, w.g.o.o.i.-p.M., R., et al., Proceedings of the American Association for Cancer Research Annual Meeting, 1998. 39: p. 641-641.
368.    Use of Nigella sativa to increase immune function Medenica, R.D. 1996. p. 1117-1117.
369.    Use of nigella sativa to increase immune function Medenica, R.D. 1997. p. 362-362.
370.    A new naturally acetylated triterpene saponin from Nigella sativa Mehta, B.K., P. Mehta, and M. Gupta, Carbohydrate Research, 2009. 344(1): p. 149-151.
371.    New principles from seeds of Nigella sativa Mehta, B.K., V. Pandit, and M. Gupta, Natural Product Research, 2009. 23(2): p. 138-148.
372.    Isolation and characterization of new compounds from seeds of Nigella sativa Mehta, B.K., et al., Medicinal Chemistry Research, 2008. 17(2-7): p. 462-473.
373.    Anti-implantation activity in Artabotrys odoratissimus leaf and Nigella sativa seed extracts Mehta, B.K., et al., Biological Memoirs, 1999. 25(1): p. 38-39.
374.    Effects of Nigella sativa L. and Urtica dioica L. on selected mineral status and hematological values in CCl4-treated rats Meral, I. and M. Kanter, Biological Trace Element Research, 2003. 96(1-3): p. 263-270.
375.    Effect of Nigella sativa on glucose concentration, l.p., anti-oxidant defence system and liver damage in experimentally-induced diabetic rabbits Meral, I., et al., Journal of Veterinary Medicine Series a-Physiology Pathology Clinical Medicine, 2001. 48(10): p. 593-599.
376.    Effect of Nigella sativa L. on heart rate and some haematological values of alloxan-induced diabetic rabbits Meral, L., et al., Scandinavian Journal of Laboratory Animal Science, 2004. 31(1): p. 49-53.
377.    Phytochemical and biological investigation of the extracts of Nigella sativa L. seed waste Michel, C.G., et al., Drug Testing and Analysis, 2011. 3(4): p. 245-254.
378.    MODULATORY EFFECTS OF CROCUS-SATIVUS AND NIGELLA-SATIVA EXTRACTS ON CISPLATIN-INDUCED TOXICITY IN MICE Nair, S.C., et al., Journal of Ethnopharmacology, 1991. 31(1): p. 75-83.
379.    Protective effects of Nigella sativa oil on propoxur-induced toxicity and oxidative stress in rat brain regions Mohamadin, A.M., et al., Pesticide Biochemistry and Physiology, 2010. 98(1): p. 128-134.
380.    The in vitro studies of schistosomicidal potency of Nigella sativa seeds against schistosoma mansoni different stages Mohamed, A.M., N.S. Metwally, and S.S. Mahmoud, Biochemical Society Transactions, 2004. 32(Part 4): p. 107A-107A.
381.    Acylated dolabellane-type diterpenes from Nigella sativa seeds with triglyceride metabolism-promoting activity in high glucose-pretreated HepG2 cells Morikawa, T., et al., Phytochemistry Letters, 2013. 6(2): p. 198-204.
382.    Novel dolabellane-type diterpene alkaloids with lipid metabolism promoting activities from the seeds of Nigella sativa Morikawa, T., et al., Organic Letters, 2004. 6(6): p. 869-872.
383.    Antimicrobial effect of crude extracts of Nigella sativa on multiple antibiotics-resistant bacteria Morsi, N.M., Acta Microbiologica Polonica, 2000. 49(1): p. 63-74.
384.    Ultrastructure alterations of adult male Schistosoma mansoni harbored in albino mice treated with Sidr honey and/or Nigella sativa oil Mostafa, O.M.S. and M.I. Soliman, Journal of King Saud University Science, 2010. 22(3): p. 111-121.
385.    Antimicrobial thymohydroquinones of Moroccan Nigella sativa seeds detected by electron spin resonance Mouhajir, F., et al., Pharmaceutical Biology, 1999. 37(5): p. 391-395.
386.    Protective Effect of Nigella sativa Extract and Thymoquinone on Serum/Glucose Deprivation-Induced PC12 Cells Death Mousavi, S.H., et al., Cellular and Molecular Neurobiology, 2010. 30(4): p. 591-598.
387.    Effects of Nigella Sativa and Albendazole alone and in combination in Toxocara Canis infected mice Musa, D., et al., Journal of the Pakistan Medical Association, 2011. 61(9): p. 866-870.
388.    Anti-Diabetic Effect of Nigella Sativa Oil in Streptozocin Induced Diabetes Mellitus in Albino Rats Nadeem, M.N., M. Purnachandrakala, and S. Mathur, Indian Journal of Pharmacology, 2013. 45: p. S173-S173.
389.    Experimental evaluation of diuretic property of Nigella sativa oil in albino rats Nadithe, L.R., P. Chinnam, and M. Mohsin, Indian Journal of Pharmacology, 2013. 45: p. S59-S59.
390.    Effects of Echinacea purpurea and Nigella sativa supplementation on broiler performance, c.a.m.q.N., Z. and M.A. Grashorn, Journal of Animal and Feed Sciences, 2010. 19(1): p. 93-103.
391.    Re: Effect of Alcoholic Extract of Nigella Sativa on Cisplatin-induced Toxicity in Rat Nematbakhsh, M. and H. Nasri, Iranian Journal of Kidney Diseases, 2013. 7(2): p. 165-166.
392.    Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein Ng, W.K., L.S. Yazan, and M. Ismail, Toxicology in Vitro, 2011. 25(7): p. 1392-1398.
393.    Endothelium-Independent Vasorelaxant Effects of Hydroalcoholic Extract from Nigella sativa Seed in Rat Aorta: The Roles of Ca2+ and K+ Channels Niazmand, S., et al., Biomed Research International, 2014.
394.    Chemical composition of the fixed and volatile oils of Nigella sativa L. from Iran Nickavar, A., et al., Zeitschrift Fur Naturforschung C-a Journal of Biosciences, 2003. 58(9-10): p. 629-631.
395.    NIGELLA-SATIVA AND CELL-MEDIATED IMMUNITY Elkadi, A., O. Kandil, and A.M. Tabuni, Archives of AIDS Research, 1987. 1(2-3): p. 232-233.
396.    Herbal treatment of allergic rhinitis: the use of Nigella sativa Nikakhlagh, S., et al., American Journal of Otolaryngology, 2011. 32(5): p. 402-407.
397.    Evaluation of the antiepileptic effect of curcumin and Nigella sativa oil in the pilocarpine model of epilepsy in comparison with valproate Noor, N.A., et al., Epilepsy & Behavior, 2012. 24(2): p. 199-206.
398.    Effects of different irrigation intervals on yield and yield components of black cumin (Nigella sativa) Noori, T.I., S.S. Rahmani, and G.K. Golezani, Planta Medica, 2011. 77(12): p. 1370-1370.
399.    Thymoquinone rich fraction from Nigella sativa and thymoquinone are cytotoxic towards colon and leukemic carcinoma cell lines Norsharina, I., et al., Journal of Medicinal Plants Research, 2011. 5(15): p. 3359-3366.
400.    Are Nigella sativa and Urtica dioica Fixed Oils Effective on Carbon Tetrachloride-Induced Liver Injury Model in Rats? Oezbek, H., et al. Phytopharmacology and Therapeutic Values I, ed. V.K. Singh, J.N. Govil, and R.K. Sharma. Vol. 19. 2008. 127-136.
401.    Antimitotic and antibacterial effects of the Nigella sativa L. seed Oezmen, A., G. Basbuelbuel, and T. Aydin, Caryologia, 2007. 60(3): p. 270-272.
402.    Antimalarial and antioxidant activities of methanolic extract of Nigella sativa seeds (black cumin) in mice infected with Plasmodium yoelli nigeriensis Okeola, V.O., et al., Parasitology Research, 2011. 108(6): p. 1507-1512.
403.    Nigella Sativa Oil as a Pulp Medicament for Pulpotomized Teeth: A Histopathological Evaluation Omar, O.M., N.M. Khattab, and D.S. Khater, Journal of Clinical Pediatric Dentistry, 2012. 36(4): p. 335-341.
404.    NIGELLA SATIVA CONCOCTION INDUCED SUSTAINED SEROREVERSION IN HIV PATIENT Onifade, A.A., A.P. Jewell, and W.A. Adedeji, African Journal of Traditional Complementary and Alternative Medicines, 2013. 10(5): p. 332-335.
405.    Amelioration by nigella sativa oil (L.) of methtrexate-induced toxicity in male albino rats: Nutritional, b.a.h.s.O., M. M. H., S.M. Abul-Nasr, and M.D.M. El-Shafey, Toxicology Letters (Shannon), 2001. 123(Supplement 1): p. 102-103.
406.    Comparison of extracts from seeds and sprouts of Nigella sativa Oshchepkova, Y.I., et al., Chemistry of Natural Compounds, 2009. 45(2): p. 293-294.
407.    Isolation of cysteine-rich peptides from Nigella sativa sprouts Oshchepkova, Y.I., et al., Chemistry of Natural Compounds, 2009. 45(5): p. 690-692.
408.    INTERACTION OF LIPID-TRANSPORT PROTEINS FROM Nigella sativa SEEDS WITH LIPID MEMBRANES Oshchepkova, Y.I., et al., Chemistry of Natural Compounds, 2010. 46(4): p. 600-603.
409.    Isolation of the lipid-transporting protein Ns-LTP1 from seeds of the garden fennel flower (Nigella sativa) Oshchepkova, Y.I., et al., Russian Journal of Bioorganic Chemistry, 2009. 35(3): p. 315-319.
410.    Comparative Analysis of Extracts of Nigella sativa Exhibiting Antifungal Activity against the Oomycete Phytophthora infestans Oshchepkova, Y.I., et al., Chemistry of Natural Compounds, 2013. 49(5): p. 985-987.
411.    The effect of Nigella sativa oil against experimental allergic encephalomyelitis via nitric oxide and other oxidative stress parameters Ozugurlu, F., et al., Cellular and Molecular Biology, 2005. 51(3): p. 337-342.
412.    Evaluation of estrogen-like activity of Nigella sativa in ovariectomized rats Parhizkar, S., et al., African Journal of Pharmacy and Pharmacology, 2011. 5(8): p. 1006-1011.
413.    Preventive effect of Nigella sativa on metabolic syndrome in menopause induced rats Parhizkar, S., et al., Journal of Medicinal Plants Research, 2011. 5(8): p. 1478-1484.
414.    Assessing estrogenic activity of Nigella sativa in ovariectomized rats using vaginal cornification assay Parhizkar, S., et al., African Journal of Pharmacy and Pharmacology, 2011. 5(2): p. 137-142.
415.    In vivo estrogenic activity of Nigella sativa different extracts using vaginal cornification assay Parhizkar, S., et al., Journal of Medicinal Plants Research, 2011. 5(32): p. 6939-6945.
416.    Effects of thymoquinone, t.m.c.o.N.s.s., on the contractile responses of rat vas deferens Parvardeh, S. and M. Fatehi, Pharmaceutical Biology, 2003. 41(8): p. 616-621.
417.    REPEATED ADMINISTRATION OF NIGELLA SATIVA DECREASES 5-HT TURNOVER AND PRODUCES ANXIOLYTIC EFFECTS IN RATS Perveen, T., et al., Pakistan Journal of Pharmaceutical Sciences, 2009. 22(2): p. 139-144.
418.    PHARMACOLOGY OF A NEW CRYSTALLINE ACTIVE PRINCIPLE (C10H1402) ISOLATED FROM SEEDS OF NIGELLA SATIVA Mahfouza.M and Eldakhak.M, Biochemical Pharmacology, 1963. 12: p. 81-&.
419.    Effect of dietary supplementation with Nigella sativa L. on serum lipid profile, l.p.a.a.d.s.i.h.r.P.-G., Bahram, et al., Journal of Medicinal Plants Research, 2009. 3(10): p. 815-821.
420.    Effectiveness, S., and Tolerability of Powdered Nigella sativa (Kalonji) Seed in Capsules on Serum Lipid Levels, Blood Sugar, Blood Pressure, and Body Weight in Adults: Results of a Randomized, Double-Blind Controlled Trial Qidwai, Waris, et al., Journal of Alternative and Complementary Medicine, 2009. 15(6): p. 639-644.
421.    Effect of Nigella sativa L. oil on roridin E toxin administration on liver of male mice Qusti, S.Y. and N.M.E.-S. Mahmoud, Journal of Applied Animal Research, 2007. 31(2): p. 161-164.
422.    Nigella sativa oil protects against reproductive toxicity of acetamiprid insecticide in male rats Rachid, M., Y.M. Ibrahim, and C. Aziez, Toxicology Letters, 2013. 221: p. S218-S218.
423.    NIGELLIMINE A NEW ISOQUINOLINE ALKALOID FROM THE SEEDS OF NIGELLA-SATIVA Rahman, A.U., S. Malik, and K. Zaman, Journal of Natural Products (Lloydia), 1992. 55(5): p. 676-678.
424.    Anti-ulcer effect of Nigella sativa Linn. against gastric ulcers in rats Rajkapoor, B., R. Anandan, and B. Jayakar, Current Science, 2002. 82(2): p. 177-179.
425.    Nutritional value, f.p.a.n.a.o.b.c.N.s.L.a.o.R., Mohamed Fawzy, International Journal of Food Science and Technology, 2007. 42(10): p. 1208-1218.
426.    Radical scavenging activity of black cumin (Nigella sativa L.), c.C.s.L., and niger (Guizotia abyssinica Cass.) crude seed oils and oil fractions Ramadan, M. F., L.W. Kroh, and J.T. Morsel, Journal of Agricultural and Food Chemistry, 2003. 51(24): p. 6961-6969.
427.    Black seed, N.s., deserves more attention Randhawa, Mohammad Akram, Journal of Ayub Medical College, Abbottabad : JAMC, 2008. 20(2): p. 1-2.
428.    AN ACTIVE PRINCIPLE OF NIGELLA SATIVA, T., INHIBITED THE GROWTH OF MYCOBACTERIUM TUBERCULOSIS Randhawa, M. A., Basic & Clinical Pharmacology & Toxicology, 2009. 105: p. 113-113.
429.    In vitro antituberculous activity of thymoquinone, a.a.p.o.N.s.R., Muhammad Akram, Journal of Ayub Medical College, Abbottabad : JAMC, 2011. 23(2): p. 78-81.
430.    Anticancer Activity of Nigella sativa (Black Seed) - A Review Randhawa, M.A. and M.S. Alghamdi, American Journal of Chinese Medicine, 2011. 39(6): p. 1075-1091.
431.    The effect of thymoquinone, a.a.c.o.N.s., on isoproterenol induced myocardial injury Randhawa, Mohammad Akram, M.S. Alghamdi, and S.K. Maulik, Pakistan Journal of Pharmaceutical Sciences, 2013. 26(6): p. 1215-1219.
432.    Enhancement of neurogenesis in middle aged rats by green tea and nigella sativa extracts Rao, M.S., et al., Society for Neuroscience Abstract Viewer and Itinerary Planner, 2013. 43.
433.    Comparative evaluation of SFE and solvent extraction methods on the yield and composition of black seeds (Nigella sativa) Rao, M.V., et al., Journal of Liquid Chromatography & Related Technologies, 2007. 30(17): p. 2545-2555.
434.    Protection against radiation-induced oxidative damage by an ethanolic extract of Nigella sativa L Rastogi, L., et al., International Journal of Radiation Biology, 2010. 86(9): p. 719-731.
435.    A review of the effects of Nigella sativa L. and its constituent, t., in metabolic syndrome Razavi, B. M. and H. Hosseinzadeh, Journal of Endocrinological Investigation, 2014. 37(11): p. 1031-1040.
436.    Nigella sativa seed extracts enhance glucose-induced insulin release from rat-isolated Langerhans islets Rchid, H., et al., Fundamental & Clinical Pharmacology, 2004. 18(5): p. 525-529.
437.    Novel antifungal defensins from Nigella sativa L. seeds Rogozhin, E.A., et al., Plant Physiology and Biochemistry, 2011. 49(2): p. 131-137.
438.    Bioassay of anti-cancer constituents of Nigella sativa, w.s.r.t.m.o.a.R., Sara and M.F. Ryan, Anticancer Research, 2004. 24(2A): p. 532-533.
439.    Modes of action of alpha-hederin and thymoquinone, a.c.o.N.s., against HEp-2 cancer cells Rooney, S. and M.F. Ryan, Anticancer Research, 2005. 25(6B): p. 4255-4259.
440.    Effects of alpha-hederin and thymoquinone, c.o.N.s., on human cancer cell lines Rooney, S. and M.F. Ryan, Anticancer Research, 2005. 25(3B): p. 2199-2204.
441.    Clinical evaluation of Nigella sativa seeds for the treatment of hyperlipidemia: a randomized, p.c.c.t.S., Ali Mohammad, et al., Medical archives (Sarajevo, Bosnia and Herzegovina), 2012. 66(3): p. 198-200.
442.    MEDICINAL PROPERTIES OF NIGELLA SATIVA (KALONJI) Saeed, S. and N.I. Khan, International Journal of Biology and Biotechnology, 2010. 7(1-2): p. 1-8.
443.    Nephro-protective effect of vitamin C and Nigella sativa oil on gentamicin associated nephrotoxicity in rabbits Saleem, U., et al., Pakistan Journal of Pharmaceutical Sciences, 2012. 25(4): p. 727-730.
444.    Comparative study of Nigella Sativa and triple therapy in eradication of Helicobacter Pylori in patients with non-ulcer dyspepsia Salem, E.M., et al., Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association, 2010. 16(3): p. 207-14.
445.    Immunomodulatory and therapeutic properties of the Nigella sativa L. seed Salem, M.L., International Immunopharmacology, 2005. 5(13-14): p. 1749-1770.
446.    Thymoquinone, t.a.i.o.N.s.s., enhances survival and activity of antigen-specific CD8-positive T cells in vitro Salem, M. L., F.Q. Alenzi, and W.Y. Attia, British Journal of Biomedical Science, 2011. 68(3): p. 131-137.
447.    Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection Salem, M.L. and M.S. Hossain, International Journal of Immunopharmacology, 2000. 22(9): p. 729-740.
448.    Cancer chemopreventive potential of volatile oil from black cumin seeds, N.s.L., in a rat multi-organ carcinogenesis bioassay Salim, Elsayed I., Oncology Letters, 2010. 1(5): p. 913-924.
449.    Chemopreventive potential of volatile oil from black cumin (Nigella sativa L.) seeds against rat colon carcinogenesis Salim, E.I. and S. Fukushima, Nutrition and Cancer-an International Journal, 2003. 45(2): p. 195-202.
450.    ANTITUMOR PRINCIPLES FROM NIGELLA-SATIVA SEEDS Salomi, N.J., et al., Cancer Letters, 1992. 63(1): p. 41-46.
451.    Cytotoxic activity of hot water and ethanloic extracts of a poly-herbal preparation comprised of Nigella sativa, H.i.a.S.g.S., S., et al., Planta Medica, 2010. 76(12): p. 1238-1238.
452.    Expression of wild type p53 is induced in HepG2 cells by a Sri Lankan herbal decoction comprised of Nigella sativa (seeds), H.i.r., and Smilax glabra (rhizome) Samarakoon, Sameera R., et al., Drug Metabolism Reviews, 2010. 42: p. 157-157.
453.    Modulation of apoptosis in human hepatocellular carcinoma (HepG2 cells) by a standardized herbal decoction of Nigella sativa seeds, H.i.r.a.S.g.r.w.a.-h.e.S., et al., Bmc Complementary and Alternative Medicine, 2012. 12.
454.    Effect of Standardized Decoction of Nigella sativa Seed, H.i.R.a.S.g.R.o.t.E.o.p.a.p.G.i.H.H.C.H.a.M., et al., Tropical Journal of Pharmaceutical Research, 2012. 11(1): p. 51-61.
455.    A standardized decoction of nigella sativa seeds, h.i.r.a.s.g.r.i.a.i.h.h.c.H.c.S., Sameera R., et al., Drug Metabolism Reviews, 2011. 43: p. 113-114.
456.    A new and novel treatment of opioid dependence: Nigella sativa 500 mg Sangi, S., et al., Journal of Ayub Medical College, Abbottabad : JAMC, 2008. 20(2): p. 118-24.
457.    Preventive effect of Nigella sativa aqueous-ethanolic extract on cisplatin-induced nephrotoxicity in the rat kidney Sara, H., et al., Clinical Biochemistry, 2011. 44(13): p. S327-S327.
458.    SARCINA-LUTEA SHIGELLA DYSENTERIAE ESCHERICHIA-COLI SHIGELLA-BOYDII SALMONELLA-TYPHI VIBRIO-CHOLERAE Bhargave, A. K., A.B.A.O.S.E.O.A.-G.-M.N.-S.-D.P.-L.-D.V.-I.-D.S.-T.-D.B.-C.B.-S.S.-A.S.-A. and C.S. Chauhan, Indian Journal of Pharmacy, 1968. 30(6): p. 150-151.
459.    Effect of Nigella sativa on experimental liver fibrosis Saricicek, E., et al., Biomedical Research-India, 2014. 25(1): p. 32-38.
460.    Potential Antihypertensive and Antioxidative Effects of Nigella sativa Seeds or Biomass and Syzygium aromaticum Extracts on L- NAME - Induced Hypertensive Rats Sayed, H.M., et al., Egyptian Journal of Pharmaceutical Sciences, 2009. 50: p. 127-146.
461.    Methyl jasmonate induced accumulation of kalopanaxsaponin I in Nigella sativa Scholz, M., et al., Phytochemistry, 2009. 70(4): p. 517-522.
462.    Neuroprotective Effect of Thymoquinone, t.N.S.B.C., in 6-Hydroxydopamine-Induced Hemi-Parkinsonian Rat Model Sedaghat, Reza, M. Roghani, and M. Khalili, Iranian Journal of Pharmaceutical Research, 2014. 13(1): p. 227-234.
463.    Nigella sativa attenuates myocardial ischemic reperfusion injury in rats Seif, A.A., Journal of Physiology and Biochemistry, 2013. 69(4): p. 937-944.
464.    Cardioprotective effects of nigella sativa on cyclosporine A-induced cardiotoxicity in rats Selcoki, Y., et al., Circulation, 2008. 118(12): p. E230-E230.
465.    Cardiovascular Benefits of Black Cumin (Nigella sativa) Shabana, A., et al., Cardiovascular Toxicology, 2013. 13(1): p. 9-21.
466.    Effect of aqueous extract from Nigella sativa L. on guinea pig isolated heart Shafei, M.N., M.H. Boskabady, and H. Parsaee, Indian Journal of Experimental Biology, 2005. 43(7): p. 635-639.
467.    Induction of apoptosis in HeLa cells by chloroform fraction of seed extracts of Nigella sativa Shafi, G., et al., Cancer Cell International, 2009. 9.
468.    Effect of gibberellic acid spray on growth, n.u.a.y.a.d.v.g.s.o.b.c.N.s.L.S., S. H., I. Ahmad, and Samiullah, Asian Journal of Plant Sciences, 2006. 5(5): p. 881-884.
469.    Influence of biotic stress induction on the and biochemical parameters of Nigella sativa Shahid, M., I. Nasir, and A. Jamil, Planta Medica, 2008. 74(9): p. 1014-1014.
470.    Acute action of Nigella sativa ethanolic-aqueous extract on clearance tests in renal ischemic-reperfusion model in the rat Shahrzad, H., et al., Clinical Biochemistry, 2011. 44(13): p. S337-S338.
471.    In vitro effect of Nigella sativa oil on adult Toxocara vitulorum Shalaby, H.A. and F.M. El-Moghazy, Pakistan journal of biological sciences: PJBS, 2013. 16(22): p. 1557-62.
472.    Chemical constituents and antimicrobial and antioxidant potentials of essential oil and acetone extract of Nigella sativa seeds Singh, G., et al., Journal of the Science of Food and Agriculture, 2005. 85(13): p. 2297-2306.
473.    Composition, I.V.A.a.A.A.o.E.O.a.O.O.f.B.C.S.N.s.L.S., Sunita, et al., Biomed Research International, 2014.
474.    Protection by Nigella sativa L. of CCL4-induced toxic nitrosative stress in rats Soleimani, H., et al., Toxicology Letters, 2008. 180: p. S39-S39.
475.    Allergic contact dermatitis from black cumin (Nigella sativa) oil after topical use Steinmann, A., et al., Contact Dermatitis, 1997. 36(5): p. 268-269.
476.    STEROLS IN SEED OIL OF NIGELLA-SATIVA Salama, R.B., Planta Medica, 1973. 24(4): p. 375-377.
477.    STUDIES ON EGYPTIAN NIGELLA SATIVA L .4. SOME PHARMACOLOGICAL PROPERTIES OF SEEDS ACTIVE PRINCIPLE IN COMPARISON TO ITS DIHYDRO COMPOUND AND ITS POLYMER Eldakhak.M, Arzneimittel-Forschung, 1965. 15(10): p. 1227-&.
478.    Supplementation of Nigella sativa fixed and essential oil mediates potassium bromate induced oxidative stress and multiple organ toxicity Sultan, M.T., et al., Pakistan Journal of Pharmaceutical Sciences, 2012. 25(1): p. 175-181.
479.    Effect of Nigella sativa fixed and essential oils on antioxidant status, h.e., and immunity in streptozotocin induced diabetes mellitus Sultan, Muhammad Tauseef, et al., Bmc Complementary and Alternative Medicine, 2014. 14.
480.    Cytotoxic and immunopotentiating effects of ethanolic extract of Nigella sativa L. seeds Swamy, S.M.K. and B.K.H. Tan, Journal of Ethnopharmacology, 2000. 70(1): p. 1-7.
481.    Cytotoxic and apoptogenic properties of Nigella sativa and thymoquinone, i.c., in human renal cell carcinoma are comparable with cisplatin Tabasi, Nafise, et al., Food and Agricultural Immunology, 2015. 26(1): p. 138-156.
482.    Black seeds (Nigella sativa) - A source of iron and antioxidants Tawab, I.A. and N. Fatima, International Journal of Biology and Biotechnology, 2006. 3(1): p. 151-155.
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484.    Beneficial Effects of Nigella Sativa Oil on Intestinal Damage in Necrotizing Enterocolitis Tayman, C., et al., Journal of Investigative Surgery, 2012. 25(5): p. 286-294.
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498.    The role of antioxidant vitamins (C and E), s.a.N.s.i.t.p.o.l.f.a.c.i.r.N.h.T., M. K., et al., Deutsche Tierarztliche Wochenschrift, 2001. 108(2): p. 71-73.
499.    The role of Urtica dioica and Nigella sativa in the prevention of carbon tetrachloride-induced hepatotoxicity in rats Turkdogan, M.K., et al., Phytotherapy Research, 2003. 17(8): p. 942-946.
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511.    Effects of Nigella sativa supplementation for one month on cardiac reserve in rats Yar, T., et al., Indian journal of physiology and pharmacology, 2008. 52(2): p. 141-8.
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515.    Indazole-Type Alkaloids from Nigella sativa Seeds Exhibit Antihyperglycemic Effects via AMPK Activation in Vitro Yuan, T., et al., Journal of Natural Products, 2014. 77(10): p. 2316-2320.
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517.    Diuretic and hypotensive effects of Nigella sativa on the spontaneously hypertensive rat Zaoui, A., et al., Therapie, 2000. 55(3): p. 379-382.
518.    Acute and chronic toxicity of Nigella sativa fixed oil Zaoui, A., et al., Phytomedicine, 2002. 9(1): p. 69-74.
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